US5502159A — Absorbable composition

Claim 1

Independent Claim 75 words

A block copolymer which comprises a proportion of units of one or more hard phase forming monomers as one of said blocks, and another of said blocks comprising a proportion of units having the formula: ##STR4## randomly combined with a proportion of units of one or more hard phase forming monomers, said hard phase forming monomer is comprising from about 1 to about 10 mole percent of the block containing units of the formula: ##STR5##

Claim 2

Dependent Claim 75 words

A block copolymer which comprises a proportion of units of one or more hard phase forming monomers as one of said blocks, and another of said blocks comprising a proportion of units having the formula: ##STR4## randomly combined with a proportion of units of one or more hard phase forming monomers, said hard phase forming monomer is comprising from about 1 to about 10 mole percent of the block containing units of the formula: ##STR5##

Claim 3

Dependent Claim 14 words

The block copolymer of claim 1 wherein said block copolymer is a triblock copolymer.

Claim 4

Dependent Claim 27 words

The block copolymer of claim 1 wherein said one or more hard phase forming monomers are selected from the group consisting of glycolide, lactide and mixtures thereof.

Claim 5

Dependent Claim 23 words

The block copolymer of claim 1 wherein lactide is the hard phase forming monomer in said block containing units of the formula: ##STR6##

Claim 6

Dependent Claim 80 words

A surgical article manufactured from a block copolymer which comprises a proportion of units of one or more hard phase forming monomers as one of said blocks, and another of said blocks comprising a proportion of units having the formula: ##STR7## randomly combined with a proportion of units of one or more hard phase forming monomers, said hard phase forming monomer is comprising from about 1 to about 10 mole percent of the block containing units of the formula: ##STR8##

Claim 7

Dependent Claim 80 words

A surgical article manufactured from a block copolymer which comprises a proportion of units of one or more hard phase forming monomers as one of said blocks, and another of said blocks comprising a proportion of units having the formula: ##STR7## randomly combined with a proportion of units of one or more hard phase forming monomers, said hard phase forming monomer is comprising from about 1 to about 10 mole percent of the block containing units of the formula: ##STR8##

Claim 8

Dependent Claim 14 words

The surgical article of claim 5 wherein said block copolymer is a triblock copolymer.

Claim 9

Dependent Claim 13 words

The surgical article of claim 5 wherein said surgical article is a suture.

Claim 10

Dependent Claim 13 words

The surgical article of claim 7 wherein said suture is a monofilament suture.

Claim 11

Dependent Claim 23 words

The surgical article of claim 5 wherein lactide is the hard phase forming monomer in said block containing units of the formula: ##STR9##

Claim 12

Independent Claim 76 words

A method for preparing a bioabsorbable block copolymer, comprising: a) polymerizing a mixture of from about 1 to about 10 mole percent of one or more hard phase forming monomers from about 9 to about 99 mole percent and 1,4-dioxan-2-one at a first reaction temperature to create a copolymer thereof; b) polymerizing one or more hard phase forming monomers with the copolymer of step (a) at a second reaction temperature to create the bioabsorbable block copolymer.

Claim 13

Independent Claim 76 words

A method for preparing a bioabsorbable block copolymer, comprising: a) polymerizing a mixture of from about 1 to about 10 mole percent of one or more hard phase forming monomers from about 9 to about 99 mole percent and 1,4-dioxan-2-one at a first reaction temperature to create a copolymer thereof; b) polymerizing one or more hard phase forming monomers with the copolymer of step (a) at a second reaction temperature to create the bioabsorbable block copolymer.

Claim 14

Dependent Claim 13 words

The method of claim 10 wherein said block copolymer is a triblock copolymer.

Claim 15

Dependent Claim 22 words

The method of claim 10 wherein said first reaction temperature comprises a temperature of from about 100° C. to about 150° C.

Claim 16

Dependent Claim 22 words

The method of claim 10 wherein said second reaction temperature comprises a temperature of from about 200° C. to about 250° C.

Claim 17

Dependent Claim 70 words

The method of claim 10 wherein step (a) is carried out in the presence of a catalyst is selected from the group consisting of stannous octoate, stannous chloride, dibutyl tin dilaurate, dibutyl tin diacetate, dibutyl tin dichloride, stannic chloride pentahydrate, aluminum isopropoxide, antimony trioxide, stannic fluoride, stannous citrate, stannous acetate, antimony trifluoride, tin tetraisopropoxide, lead oxide, tetraisopropyl titanate, titanium acetyl acetonate, tetraoctylene glycol titanate, boron trifluoride etherate, and aluminum trichloride.

Claim 18

Independent Claim 85 words

A method for making a bioabsorbable surgical article, comprising: a) polymerizing a mixture of from about 1 to about 10 mole percent of one or more hard phase forming monomers and from about 90 to about 99 mole percent 1,4-dioxan-2-one at a first reaction temperature to create a copolymer thereof; b) polymerizing one or more hard phase forming monomers with the copolymer of step (a) at a second reaction temperature to create a bioabsorbable block copolymer; c) forming a surgical article from said block copolymer.

Claim 19

Independent Claim 85 words

A method for making a bioabsorbable surgical article, comprising: a) polymerizing a mixture of from about 1 to about 10 mole percent of one or more hard phase forming monomers and from about 90 to about 99 mole percent 1,4-dioxan-2-one at a first reaction temperature to create a copolymer thereof; b) polymerizing one or more hard phase forming monomers with the copolymer of step (a) at a second reaction temperature to create a bioabsorbable block copolymer; c) forming a surgical article from said block copolymer.

Claim 20

Dependent Claim 19 words

The method of claim 15 wherein lactide is used as the hard phase forming monomer is said step (a).

Claim 21

Dependent Claim 19 words

The method of claim 16 wherein glycolide is used as the hard phase forming monomer in said step (b).

Claim 22

Dependent Claim 19 words

The method of claim 15 wherein said forming includes the step of extruding the block copolymer into a filament.

Claim 23

Dependent Claim 13 words

The method of claim 18 wherein the bioabsorbable surgical article comprises a suture.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	1999-03-26	1999-09-25	2000-03-26	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	2003-03-26	2003-09-25	2004-03-26	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	2007-03-26	2007-09-25	2008-03-26	$7700.00	Window Closed / Lapsed

Absorbable composition

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