US4716203A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Diblock and triblock copolymers
Assignee: Covidien AG
•
Filing: 1986-09-05
•
Granted: 1987-12-29
•
Expires: 2006-09-05
Abstract
Abstract A diblock copolymer is disclosed having a first block of a polyalkylene oxide and a second block of glycolic acid ester and trimethylene carbonate linkages. A triblock copolymer is disclosed having a middle block obtained from an ethylene oxide homopolymer or a copolymer of ethylene oxide and a cyclic ether. Alternatively, the triblock copolymer middle block is obtained from a copolymer of formula (I): ##STR1## and formula (II): ##STR2## The copolymers are useful in medical and surgical applications.
Inventors
- 👤 Donald J. Casey
- 👤 Peter K. Jarrett
- 👤 Louis Rosati
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 19:38
CPC Classifications
C; C08; C08G; C08G65/00; C08G65/02; C08G65/04; C08G65/06; C08G65/16; A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2031; A61K9/204; A61K9/70; C08G64/00; C08G64/18; C08G64/183; Y; Y10; Y10S; Y10S524/00; Y10S524/916
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
25 words
A diblock copolymer having a first block comprising a polyalkylene oxide and a second block consisting essentially of glycolic acid ester and trimethylene carbonate linkages.
Claim 2
Dependent Claim
25 words
A diblock copolymer having a first block comprising a polyalkylene oxide and a second block consisting essentially of glycolic acid ester and trimethylene carbonate linkages.
Claim 3
Dependent Claim
22 words
A diblock copolymer of claim 1 wherein the polyalkylene oxide block is from 5 to 25 percent by weight of the copolymer.
Claim 4
Dependent Claim
25 words
A diblock copolymer of claim 1 or 2 wherein the number average molecular weight of the polyalkylene oxide block is from about 4,000 to 30,000.
Claim 5
Dependent Claim
41 words
A diblock copolymer of claim 1 or 3 wherein the polyalkylene oxide block is derived from a polyalkylene oxide terminated on one end by a C 1 to C 6 alkyl group and on the other end by a hydroxyl group.
Claim 6
Dependent Claim
19 words
A diblock copolymer of claim 4 wherein the polyalkylene oxide block is derived from a homopolymer of ethylene oxide.
Claim 7
Dependent Claim
30 words
A diblock copolymer of claim 4 wherein the polyalkylene oxide block is derived from a block or random copolymer of ethylene oxide, and a cyclic ether other than ethylene oxide.
Claim 8
Dependent Claim
42 words
A diblock copolymer of claim 6 wherein the cyclic ether is selected from the group consisting of ##STR12## wherein x is 2 to about 9, y is 1 to about 9 and R is a C 1 to C 6 alkyl group.
Claim 9
Dependent Claim
68 words
A diblock copolymer of claim 4 wherein the polyalkylene oxide block is derived from a block or random copolymer of a first cyclic ether selected from the group consisting of ##STR13## wherein x is 2 to about 9, and a second cyclic ether selected from the group consisting of ##STR14## wherein y is 1 to about 9 and R is a C 1 to C 6 alkyl group.
Claim 10
Dependent Claim
39 words
A bioabsorbable diblock copolymer of claim 5 or 7 or 8 wherein the inherent viscosity of the copolymer, as measured at 30° C. for a 0.5% (w/v) solution in chloroform or methylene chloride, is 0.25 to about 1.50 dl/g.
Claim 11
Dependent Claim
39 words
A triblock copolymer useful in nonfiber form having a middle block obtained by removing both terminal hydroxyl hydrogens from either a homopolymer of ethylene oxide, or from a block or random copolymer of ethylene oxide and a cyclic ether.
Claim 12
Dependent Claim
39 words
A triblock copolymer useful in nonfiber form having a middle block obtained by removing both terminal hydroxyl hydrogens from either a homopolymer of ethylene oxide, or from a block or random copolymer of ethylene oxide and a cyclic ether.
Claim 13
Dependent Claim
42 words
A triblock copolymer of claim 10 wherein the cyclic ether is selected from the group consisting of ##STR15## wherein x is 2 to about 9, y is 1 to about 9 and R is a C 1 to C 6 alkyl group.
Claim 14
Dependent Claim
73 words
A triblock copolymer useful in nonfiber form having a middle block obtained by removing both terminal hydroxyl hydrogens from a block or random copolymer of a first cyclic ether selected from the group consisting of ##STR16## wherein x is 2 to about 9, and a second cyclic ether selected from the group consisting of ##STR17## wherein y is 1 to about 9 and R is a C 1 to C 6 alkyl group.
Claim 15
Dependent Claim
73 words
A triblock copolymer useful in nonfiber form having a middle block obtained by removing both terminal hydroxyl hydrogens from a block or random copolymer of a first cyclic ether selected from the group consisting of ##STR16## wherein x is 2 to about 9, and a second cyclic ether selected from the group consisting of ##STR17## wherein y is 1 to about 9 and R is a C 1 to C 6 alkyl group.
Claim 16
Dependent Claim
26 words
A triblock copolymer of claim 11 or 12 wherein each end block of the triblock copolymer consists essentially of glycolic acid ester and trimethylene carbonate linkages.
Claim 17
Dependent Claim
25 words
A triblock copolymer of claim 11 or 12 or 13 wherein the middle block is from 5 to 25 percent by weight of the copolymer.
Claim 18
Dependent Claim
22 words
A triblock copolymer of claim 14 wherein the number average molecular weight of the middle block is from about 4,000 to 30,000.
Claim 19
Dependent Claim
35 words
A bioabsorbable triblock copolymer of claim 15 wherein the inherent viscosity of the copolymer, as measured at 30° C. for a 0.5% (w/v) solution in chloroform or methylene chloride, is 0.25 to about 1.50 dl/g.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-12-28 | 1991-06-29 | 1991-12-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-12-28 | 1995-06-29 | 1995-12-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-12-28 | 1999-06-29 | 1999-12-29 | $7700.00 | Window Closed / Lapsed |