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US5007923A
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Crystalline copolyesters of amorphous (lactide/glycolide) and p-dioxanone
Assignee: Ethicon Inc
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Filing: 1990-01-31
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Granted: 1991-04-16
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Expires: 2010-01-31
Abstract
Abstract A crystalline copolyester of p-diaxanone and a prepolymer of lactide and glycolide, and absorbable surgical filaments derived therefrom.
Inventors
- 👤 Rao S. Bezwada
- 👤 Hugh D. Newman, Jr.
- 👤 Shalaby W. Shalaby
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:37
CPC Classifications
A; A61; A61L; A61L17/00; A61L17/06; A61L17/10; A61L17/105; A61B; A61B17/00; A61B17/04; A61B17/06; A61B17/06166; A61L17/12; C; C08; C08G; C08G63/00; C08G63/02; C08G63/06; C08G63/08; C08G63/66; C08G63/664
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
50 words
A crystalline copolyester of p-dioxanone and an amount of an amorphous prepolymer of lactide and glycolide effective to modify the in vivo breaking strength retention and in vivo absorption profile of the copolyester relative to the in vivo breaking strength retention and in vivo absorption profile of a p-dioxanone homopolymer.
Claim 2
Dependent Claim
50 words
A crystalline copolyester of p-dioxanone and an amount of an amorphous prepolymer of lactide and glycolide effective to modify the in vivo breaking strength retention and in vivo absorption profile of the copolyester relative to the in vivo breaking strength retention and in vivo absorption profile of a p-dioxanone homopolymer.
Claim 3
Dependent Claim
23 words
The crystalline copolyester of claim 1 wherein the crystallinity of the copolymer is greater than about 10 percent as measured by x-ray diffraction.
Claim 4
Dependent Claim
21 words
The crystalline copolyester of claim 2 wherein the intrinsic viscosity of the copolymer ranges from about 1.2 to about 2.0 dl/g.
Claim 5
Dependent Claim
20 words
The crystalline copolyester of claim 1 wherein the amount of prepolymer ranges from about 5 to about 50 weight percent.
Claim 6
Dependent Claim
20 words
The crystalline copolyester of claim 4 wherein the amount of prepolymer ranges from about 10 to about 20 weight percent.
Claim 7
Dependent Claim
21 words
The crystalline copolyester of claim 5 wherein the mole ratio of lactide to glycolide ranges from about 60/40 to about 70/30.
Claim 8
Dependent Claim
16 words
An absorbable surgical filament prepared by melt spinning the crystalline copolyester of claim 1 or 6.
Claim 9
Dependent Claim
27 words
The surgical filament of claim 7 wherein the filament exhibits a straight tensile strength greater than 40,000 psi and a knot tensile strength greater than 30,000 psi.
Claim 10
Dependent Claim
27 words
The surgical filament of claim 8 wherein the filament exhibits a straight tensile strength greater than 50,000 psi and a knot tensile strength greater than 40,000 psi.
Claim 11
Dependent Claim
24 words
The surgical filament of claim 9 wherein the filament exhibits a Young's Modulus less than 500,000 psi and an elongation less than 80 percent.
Claim 12
Dependent Claim
24 words
The surgical filament of claim 10 wherein the filament exhibits a Young's Modulus less than 300,000 psi and an elongation less than 60 percent.
Claim 13
Dependent Claim
16 words
The surgical filament of claim 11 wherein the filament is in the form of a monofilament.
Claim 14
Dependent Claim
16 words
The surgical filament of claim 12 wherein the filament is in the form of a suture.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-04-15 | 1994-10-15 | 1995-04-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-04-15 | 1998-10-15 | 1999-04-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-04-15 | 2002-10-15 | 2003-04-16 | $7700.00 | Window Closed / Lapsed |