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Textured bone allograft, method of making and using same

Assignee: DePuy Spine LLC
•
Filing: 1998-05-07
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Granted: 2003-01-28
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Expires: 2018-05-07
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Abstract

Abstract The present invention is directed to a textured bone allograft for implantation in a patient, having one or more textured bone surfaces, and methods of making and using the textured bone graft. The textured surface preferably includes a plurality of closely spaced discrete, continuous, or a combination thereof, protrusions. The textured bone allograft is useful for repairing bone defects caused by congenital anomaly, disease, or trauma, in a patient, for example, for restoring vertical support of the anterior column. Implantation of the textured bone allograft results in improved graft stability and osteoinductivity, without a decrease in mechanical strength. The textured bone allograft does not shift, extrude or rotate, after implantation.

Inventors

  • 👤 Louis Ford
  • 👤 Lloyd Wolfinbarger, Jr.
  • 👤 Jon C. Serbousek
  • 👤 Laine Mashburn, Jr.

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 22:04
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/44; A61F2/4455; A61F2/4465; A61F2/28; A61F2002/2825; A61F2002/2835; A61F2002/2839; A61F2002/2853; A61F2002/30001; A61F2002/30108; A61F2002/3011; A61F2002/30112; A61F2002/30113; A61F2002/30125; A61F2002/30138; A61F2002/30153; A61F2002/30154; A61F2002/30156; A61F2002/30158; A61F2002/30199; A61F2002/30205; A61F2002/30224; A61F2002/30235; A61F2002/30261; A61F2002/30263; A61F2002/30273; A61F2/30767; A61F2/30771; A61F2002/30841; A61F2002/30843; A61F2002/30878; A61F2002/30879; A61F2002/30891; A61F2002/30892; A61F2/46; A61F2/4644; A61F2002/4649; A61F2230/00; A61F2230/0002; A61F2230/0004; A61F2230/0006; A61F2230/0008; A61F2230/0017; A61F2230/0019; A61F2230/0021; A61F2230/0023; A61F2230/0026; A61F2230/0063; A61F2230/0067; A61F2230/0069; A61F2230/0082; A61F2230/0084; A61F2230/0086

Claims Analysis

Total Claims: 28
Claim 1
Independent Claim 18 words
A textured bone allograft comprising: a plurality of closely spaced protrusions, each protrusion comprising a triangular shaped cross-section.
Claim 2
Dependent Claim 18 words
A textured bone allograft comprising: a plurality of closely spaced protrusions, each protrusion comprising a triangular shaped cross-section.
Claim 3
Dependent Claim 30 words
The textured bone allograft of claim 1 , said plurality of closely spaced protrusions comprise a plurality of closely spaced discrete protrusions or a plurality of closely spaced continuous protrusions.
Claim 4
Dependent Claim 25 words
The textured bone allograft of claim 2 , said plurality of closely spaced protrusions are provided on one or more surfaces of said bone allograft.
Claim 5
Dependent Claim 22 words
The textured bone allograft of claim 2 , said plurality of closely spaced protrusions comprise a plurality of closely spaced discrete protrusions.
Claim 6
Dependent Claim 17 words
The textured bone allograft of claim 2 , said closely spaced protrusions comprise closely spaced continuous protrusions.
Claim 7
Dependent Claim 22 words
The textured bone allograft of claim 4 , said closely spaced discrete protrusions comprising a plurality of closely spaced discrete pyramidal protrusions.
Claim 8
Dependent Claim 22 words
The textured bone allograft of claim 4 , said closely spaced discrete protrusions comprising a plurality of closely spaced discrete conical protrusions.
Claim 9
Dependent Claim 15 words
The textured bone allograft of claim 5 , said closely spaced continuous protrusions are linear.
Claim 10
Dependent Claim 15 words
The textured bone allograft of claim 5 , said closely spaced continuous protrusions are nonlinear.
Claim 11
Dependent Claim 35 words
The textured bone allograft of any one of claims 1 , 2 , 4 , or 5 , said plurality of closely spaced protrusions are spaced from about 0.0 mm to about 3.0 mm apart.
Claim 12
Dependent Claim 25 words
The textured bone allograft of claim 10 , said plurality of closely spaced protrusions are spaced from about 0.1 mm to about 2.0 mm apart.
Claim 13
Dependent Claim 20 words
The textured bone allograft of claim 11 , said plurality of closely spaced protrusions are spaced about 0.5 mm apart.
Claim 14
Dependent Claim 35 words
The textured bone allograft of any one of claims 1 , 2 , 4 , or 5 , said plurality of closely spaced protrusions are from about 0.1 mm to about 5.0 mm in height.
Claim 15
Dependent Claim 25 words
The textured bone allograft of claim 13 , said plurality of closely spaced protrusions are from about 0.3 mm to about 3.0 mm in height.
Claim 16
Dependent Claim 24 words
The textured bone allograft of claim 14 said plurality of closely spaced protrusions are from about 0.5 mm to about 2.0 mm in height.
Claim 17
Dependent Claim 90 words
The textured bone allograft of any one of claims 1 , 2 , 4 , or 5 , said bone allograft is selected from the group consisting of: a fibular wedge; a humeral wedge; a tibial wedge; a fibular trapezoid wedge; a humeral trapezoid wedge; a femoral wedge; a femoral trapezoid wedge; a fibular ring; a fibular shaft; a humeral ring; a humeral shaft; a femoral ring; a femoral shaft; a cancellous cube, a Cloward dowel; an iliac crest wedge; a proximal femur; a distal femur; and a femoral head.
Claim 18
Dependent Claim 25 words
The textured bone allograft of claim 3 , said plurality of protrusions are provided on at least one entire cut surface of said bone allograft.
Claim 19
Dependent Claim 48 words
The textured bone allograft of claim 4 , said plurality of closely spaced discrete protrusions are sized to be in a range offrom about 0.5 mm to about 10.0 mm in length, 0.5 mm to about 10.0 mm in width, and 0.1 to about 5.0 mm in height.
Claim 20
Dependent Claim 49 words
The textured bone allograft of claim 18 , said plurality of closely spaced discrete protrusions are sized to be in a range of from about 1.5 mm to about 5.0 mm in length, 1.5 mm to about 5.0 mm in width, and 0.5 to about 2.0 mm in height.
Claim 21
Dependent Claim 50 words
The textured bone allograft of claim 5 , said plurality of closely spaced continuous protrusions are sized to be in a range of from greater than or equal to about 1.5 mm in length, 0.5 mm to about 10.0 mm in width, and 0.1 to about 5.0 mm in height.
Claim 22
Dependent Claim 50 words
The textured bone allograft of claim 20 , said plurality of closely spaced continuous protrusions are sized to be in a range of from greater than or equal to about 4.5 mm in length, 1.5 mm to about 5.0 mm in width, and 0.5 to about 2.0 mm in height.
Claim 23
Dependent Claim 32 words
The textured bone allograft of any one of claims 1 , 2 , 4 , or 5 , said plurality of protrusions are provided perpendicular to a surface of said bone allograft.
Claim 24
Independent Claim 53 words
A method for restoring vertical support of the anterior column, comprising: implanting a textured bone allograft comprising a plurality of closely spaced protrusions, each protrusion comprising a triangular shaped cross-section, said plurality of closely spaced discrete protrusions provided on one or more surfaces of said bone allograft, at a site in a patient.
Claim 25
Independent Claim 53 words
A method for restoring vertical support of the anterior column, comprising: implanting a textured bone allograft comprising a plurality of closely spaced protrusions, each protrusion comprising a triangular shaped cross-section, said plurality of closely spaced discrete protrusions provided on one or more surfaces of said bone allograft, at a site in a patient.
Claim 26
Independent Claim 36 words
A method of making a textured bone allograft, comprising: providing said bone allograft with a plurality of closely spaced protrusions each protrusion comprising a triangular shaped cross-section, on one or more surfaces of said bone allograft.
Claim 27
Independent Claim 36 words
A method of making a textured bone allograft, comprising: providing said bone allograft with a plurality of closely spaced protrusions each protrusion comprising a triangular shaped cross-section, on one or more surfaces of said bone allograft.
Claim 28
Independent Claim 21 words
The method of any one of claims 23 or 24 , said closely spaced protrusions comprise discrete protrusions or continuous protrusions.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2006-01-27 2006-07-29 2007-01-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2010-01-27 2010-07-29 2011-01-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2014-01-27 2014-07-29 2015-01-28 $7700.00 Window Closed / Lapsed

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