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US5264105A Expired / Lapsed US ⏱️ 0.0 years remaining

Enzyme electrodes

Assignee: Therasense Inc
•
Filing: 1993-03-17
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Granted: 1993-11-23
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Expires: 2013-03-17
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Abstract

Abstract An improved enzyme electrode includes a three-dimensional redox polymer network having redox enzymes bound thereto, and also having a protein excluding polymeric coating.

Inventors

  • 👤 Brian A. Gregg
  • 👤 Adam Heller
  • 👤 Wolfgang Kerner
  • 👤 Michael V. Pishko
  • 👤 Ioanis Katakis

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 18:32
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/001; C12Q1/002; Y; Y10; Y10S; Y10S435/00; Y10S435/817

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 74 words
An enzyme electrode comprising: an electrode having a testing surface; a transducing film covering the testing surface, which film comprises a cross-linked redox polymer network to which a redox enzyme is chemically bound, wherein the redox enzyme electrically communicates through the film with the electrode thereby transducing substrate flux to an electrical current; and a polymeric film covering the transducing film and excluding from the transducing film proteins of molecular weights exceeding 5000 daltons.
Claim 2
Dependent Claim 74 words
An enzyme electrode comprising: an electrode having a testing surface; a transducing film covering the testing surface, which film comprises a cross-linked redox polymer network to which a redox enzyme is chemically bound, wherein the redox enzyme electrically communicates through the film with the electrode thereby transducing substrate flux to an electrical current; and a polymeric film covering the transducing film and excluding from the transducing film proteins of molecular weights exceeding 5000 daltons.
Claim 3
Dependent Claim 12 words
The enzyme electrode of claim 1, wherein the polymeric film is polyurethane.
Claim 4
Dependent Claim 14 words
The enzyme electrode of claim 2, wherein the polymeric film further includes palmitic acid.
Claim 5
Dependent Claim 12 words
The enzyme electrode of claim 1, wherein the polymeric film is polycarbonate.
Claim 6
Dependent Claim 20 words
The enzyme electrode of claim 1, wherein the polymeric film includes multiple anionic functions covalently bound to the polymeric film.
Claim 7
Dependent Claim 24 words
The enzyme electrode of claim 5, wherein the polymeric film includes multiple carboxylate, sulfonate, phosphate, or phosphonate functions covalently bound to the polymeric film.
Claim 8
Dependent Claim 12 words
The enzyme electrode of claim 6, wherein the polymeric film contains fluorine.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-11-22 1997-05-24 1997-11-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-11-22 2001-05-24 2001-11-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-11-22 2005-05-24 2005-11-23 $7700.00 Window Closed / Lapsed

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