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US5082786A Expired / Lapsed US ⏱️ 0.0 years remaining

Glucose sensor with gel-immobilized glucose oxidase and gluconolactonase

Assignee: NEC Corp
•
Filing: 1988-11-28
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Granted: 1992-01-21
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Expires: 2008-11-28
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Abstract

Abstract A glucose sensor in which a gel is in contact with a pH sensing element. The gel contains immobilized glucose oxidase and gluconolactonase (EC 3.1.1.17). Gluconolactonase is present in an amount effective to accelerate the hydrolysis of D-glucono-δ-lactone.

Inventors

  • 👤 Shinya Nakamoto

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 17:40
CPC Classifications
C; C12; C12M; C12M21/00; C12M21/18; C12M25/00; C12M25/14; C12M41/00; C12M41/26; C12Q; C12Q1/00; C12Q1/001; C12Q1/005; C12Q1/006; Y; Y10; Y10S; Y10S435/00; Y10S435/817

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 42 words
A glucose sensor comprising (1) a gel in which glucose oxidase is immobilized and (2) a pH sensing element in sensing contact with said gel wherein said gel contains gluconolactonase (EC 3.1.1.17) in an amount effective to accelerate the hydrolysis of D-glucono-δ-lactone.
Claim 2
Dependent Claim 42 words
A glucose sensor comprising (1) a gel in which glucose oxidase is immobilized and (2) a pH sensing element in sensing contact with said gel wherein said gel contains gluconolactonase (EC 3.1.1.17) in an amount effective to accelerate the hydrolysis of D-glucono-δ-lactone.
Claim 3
Dependent Claim 17 words
A glucose sensor as set forth in claim 1 wherein the pH sensing element is a pH-ISFET.
Claim 4
Dependent Claim 19 words
A glucose sensor as set forth in claim 1 wherein the pH sensing element is a pH glass electrode.
Claim 5
Dependent Claim 15 words
A glucose sensor as set forth in claim 1 wherein the gel contains crosslinkable polymer.
Claim 6
Dependent Claim 45 words
A glucose sensor as set forth in claim 1 wherein said gluconolactonase amount in said gel is in an amount of more than 500 units per one cubic centimeter up to a limit in which concentration is still effective to accelerate the hydrolysis of D-glucono-δ-lactone.

References Cited (Backward Citations)

US4601981A Cited
US4066512A Cited
US4224125A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-01-20 1995-07-22 1996-01-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-01-20 1999-07-22 2000-01-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-01-20 2003-07-22 2004-01-21 $7700.00 Window Closed / Lapsed

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