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US5082786A
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Glucose sensor with gel-immobilized glucose oxidase and gluconolactonase
Assignee: NEC Corp
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Filing: 1988-11-28
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Granted: 1992-01-21
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Expires: 2008-11-28
Abstract
Abstract A glucose sensor in which a gel is in contact with a pH sensing element. The gel contains immobilized glucose oxidase and gluconolactonase (EC 3.1.1.17). Gluconolactonase is present in an amount effective to accelerate the hydrolysis of D-glucono-δ-lactone.
Inventors
- 👤 Shinya Nakamoto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 20:10
CPC Classifications
C; C12; C12M; C12M21/00; C12M21/18; C12M25/00; C12M25/14; C12M41/00; C12M41/26; C12Q; C12Q1/00; C12Q1/001; C12Q1/005; C12Q1/006; Y; Y10; Y10S; Y10S435/00; Y10S435/817
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
42 words
A glucose sensor comprising (1) a gel in which glucose oxidase is immobilized and (2) a pH sensing element in sensing contact with said gel wherein said gel contains gluconolactonase (EC 3.1.1.17) in an amount effective to accelerate the hydrolysis of D-glucono-δ-lactone.
Claim 2
Dependent Claim
42 words
A glucose sensor comprising (1) a gel in which glucose oxidase is immobilized and (2) a pH sensing element in sensing contact with said gel wherein said gel contains gluconolactonase (EC 3.1.1.17) in an amount effective to accelerate the hydrolysis of D-glucono-δ-lactone.
Claim 3
Dependent Claim
17 words
A glucose sensor as set forth in claim 1 wherein the pH sensing element is a pH-ISFET.
Claim 4
Dependent Claim
19 words
A glucose sensor as set forth in claim 1 wherein the pH sensing element is a pH glass electrode.
Claim 5
Dependent Claim
15 words
A glucose sensor as set forth in claim 1 wherein the gel contains crosslinkable polymer.
Claim 6
Dependent Claim
45 words
A glucose sensor as set forth in claim 1 wherein said gluconolactonase amount in said gel is in an amount of more than 500 units per one cubic centimeter up to a limit in which concentration is still effective to accelerate the hydrolysis of D-glucono-δ-lactone.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-01-20 | 1995-07-22 | 1996-01-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-01-20 | 1999-07-22 | 2000-01-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-01-20 | 2003-07-22 | 2004-01-21 | $7700.00 | Window Closed / Lapsed |