Patent US6869443B2 successfully refreshed from Google Patents.
US6869443B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biodegradable drug delivery vascular stent
Assignee: Boston Scientific Scimed Inc
•
Filing: 2002-03-28
•
Granted: 2005-03-22
•
Expires: 2022-03-28
Abstract
Abstract A stent includes a main body of a generally tubular shape for insertion into a lumen of a vessel of a living being. The tubular main body includes a substantially biodegradable matrix having collagen IV and laminin that enclose voids within the matrix. The tubular main body also includes a biodegradable strengthening material in contact with the matrix to strengthen the matrix. The tubular main body is essentially saturated with drugs.
Inventors
- 👤 Paul J. Buscemi
- 👤 Elizabeth A. Stejskal
- 👤 II Donald F. Palme
- 👤 Lixiao Wang
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 07:51
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/86; A61F2/88; A61L; A61L31/00; A61L31/04; A61L31/041; A61L31/043; A61L31/044; A61L31/047; A61L31/14; A61L31/148; A61L31/16; A61F2/95; A61F2/958; A61F2210/00; A61F2210/0004; A61F2210/0014; A61F2210/0023; A61F2250/00; A61F2250/0058; A61F2250/0067; A61F2250/0068; A61L2300/00; A61L2300/40; A61L2300/42; A61L2300/60; A61L2300/602; A61L2300/604; A61L2300/606; A61L2300/62; A61L2300/622; Y; Y10; Y10S; Y10S623/00; Y10S623/901
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
72 words
A method of making a biodegradable stent comprising: forming a biodegradable material into a generally tubular main body for insertion into a body lumen of a living being wherein the body lumen has a lumen wall, the tubular main body has an outer surface, and the biodegradable material comprises: a substantially biodegradable matrix comprising collagen IV, laminin, and one or more drugs; and a biodegradable strengthening material in contact with the matrix.
Claim 2
Independent Claim
72 words
A method of making a biodegradable stent comprising: forming a biodegradable material into a generally tubular main body for insertion into a body lumen of a living being wherein the body lumen has a lumen wall, the tubular main body has an outer surface, and the biodegradable material comprises: a substantially biodegradable matrix comprising collagen IV, laminin, and one or more drugs; and a biodegradable strengthening material in contact with the matrix.
Claim 3
Dependent Claim
14 words
The method of claim 1 , wherein the biodegradable strengthening material comprises polylactic acid.
Claim 4
Dependent Claim
15 words
The method of claim 1 , wherein the drugs comprise a plurality of microencapsulated drugs.
Claim 5
Dependent Claim
14 words
The method of claim 1 , wherein the biodegradable matrix further comprises a glycosaminoglucuronan.
Claim 6
Dependent Claim
11 words
The method of claim 4 , wherein the glycosaminoglucuronan comprises heparin.
Claim 7
Dependent Claim
15 words
The method of claim 1 , wherein the tubular main body is a coiled strip.
Claim 8
Dependent Claim
32 words
The method of claim 1 , further comprising treating the biodegradable material with an application of energy of a magnitude ineffective to cause bonding between the biodegradable material and the lumen wall.
Claim 9
Dependent Claim
27 words
The method of claim 7 , wherein the energy causes an increase in temperature of the biodegradable material above the glass transition temperature of the biodegradable material.
Claim 10
Dependent Claim
30 words
The method of claim 7 , wherein the biodegradable material is treated with an application of mechanical energy of a magnitude less than the elastic limit of the biodegradable material.
Claim 11
Independent Claim
104 words
A method of making a biodegradable stent comprising: forming a biodegradable material by contacting a substantially biodegradable matrix with a biodegradable strengthening material to strengthen the matrix, wherein the biodegradable strengthening material includes a plurality of microcapsules containing a material capable of inducing crosslinking of the biodegradable strengthening material; forming the biodegradable material into a generally tubular main body in the form of a coiled strip for insertion into a lumen of a vessel; applying energy to the biodegradable material, wherein the application of energy causes a rupture of the microcapsules and a release of the material inducing crosslinking of the biodegradable strengthening material.
Claim 12
Independent Claim
104 words
A method of making a biodegradable stent comprising: forming a biodegradable material by contacting a substantially biodegradable matrix with a biodegradable strengthening material to strengthen the matrix, wherein the biodegradable strengthening material includes a plurality of microcapsules containing a material capable of inducing crosslinking of the biodegradable strengthening material; forming the biodegradable material into a generally tubular main body in the form of a coiled strip for insertion into a lumen of a vessel; applying energy to the biodegradable material, wherein the application of energy causes a rupture of the microcapsules and a release of the material inducing crosslinking of the biodegradable strengthening material.
Claim 13
Dependent Claim
15 words
The method of claim 10 , wherein the tubular main body is saturated with drugs.
Claim 14
Dependent Claim
12 words
The method of claim 10 , wherein the matrix comprises voids therein.
Claim 15
Dependent Claim
14 words
The method of claim 10 , wherein the matrix comprises collagen IV and laminin.
Claim 16
Dependent Claim
27 words
The method of claim 10 , wherein the energy causes an increase in temperature of the biodegradable material above the glass transition temperature of the biodegradable material.
Claim 17
Dependent Claim
30 words
The method of claim 10 , wherein the biodegradable material is treated with an application of mechanical energy of a magnitude less than the elastic limit of the biodegradable material.
Claim 18
Dependent Claim
67 words
A biodegradable stent made by the process comprising: forming a biodegradable material into a generally tubular main body for insertion into a body lumen of a living being, wherein the tubular main body has an outer surface, and the biodegradable material comprises: a substantially biodegradable matrix comprising collagen IV, laminin, and a drug; and a biodegradable strengthening material in contact with the matrix to strengthen the matrix.
Claim 19
Dependent Claim
67 words
A biodegradable stent made by the process comprising: forming a biodegradable material into a generally tubular main body for insertion into a body lumen of a living being, wherein the tubular main body has an outer surface, and the biodegradable material comprises: a substantially biodegradable matrix comprising collagen IV, laminin, and a drug; and a biodegradable strengthening material in contact with the matrix to strengthen the matrix.
Claim 20
Dependent Claim
15 words
The biodegradable stent of claim 16 , wherein the biodegradable strengthening material comprises polylactic acid.
Claim 21
Dependent Claim
16 words
The biodegradable stent of claim 16 , wherein the drug comprises a plurality of microencapsulated drugs.
Claim 22
Dependent Claim
15 words
The biodegradable stent of claim 16 , wherein the biodegradable matrix further comprises a glycosaminoglucuronan.
Claim 23
Dependent Claim
12 words
The biodegradable stent of claim 19 , wherein the glycosaminoglucuronan comprises heparin.
References Cited (Backward Citations)
US2836181A
Cited
US4057537A
Cited
US4470407A
Cited
US4550447A
Cited
US4799479A
Cited
US4690684A
Cited
US4770176A
Cited
US5061281A
Cited
US4768507A
Cited
US4740207A
Cited
US5092885A
Cited
US4907336A
Cited
US6387379B1
Cited
US4886062A
Cited
US4820298A
Cited
US4950258A
Cited
US4830003A
Cited
US5575815A
Cited
US5024671A
Cited
US4950227A
Cited
US5032679A
Cited
US5100429A
Cited
US4990155A
Cited
US4994033A
Cited
US5116318A
Cited
US5201778A
Cited
US5092841A
Cited
US5139480A
Cited
US5344425A
Cited
US5108417A
Cited
US5147370A
Cited
US5500013A
Cited
US5769883A
Cited
US5968092A
Cited
US6387124B1
Cited
US5234457A
Cited
US5376276A
Cited
US6121027A
Cited
US6129757A
Cited
US6596296B1
Cited
US20030175410A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2008-03-21 | 2008-09-20 | 2009-03-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2012-03-21 | 2012-09-20 | 2013-03-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2016-03-21 | 2016-09-20 | 2017-03-22 | $7700.00 | Window Closed / Lapsed |