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US5201778A Expired / Lapsed US ⏱️ 0.0 years remaining

Vascular prosthesis containing in the wall microcapsules, including hormone-producing cells

Assignee: Individual
•
Filing: 1992-01-13
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Granted: 1993-04-13
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Expires: 2012-01-13
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Abstract

Abstract A vascular prosthesis having a low porosity outer material such as PTFE, and an inner synthetic tubular mesh. Semi-permeable microcapsules that contain hormone-producing cells, are placed between the outer material and the inner mesh. The microcapsules are preferably made of polysaccharides or amino-acid polymers.

Inventors

  • 👤 Giovanni Brotzu
  • 👤 Riccardo Calafiore

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 00:27
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/54; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L27/507; A61L2300/00; A61L2300/40; A61L2300/43; A61L2300/60; A61L2300/62; A61L2300/622; A61L2300/64; Y; Y10; Y10S; Y10S623/00; Y10S623/92; Y10S623/921

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 81 words
A process for the preparation of a vascular prosthesis comprising: forming an outer material having a low porosity and an inner tubular porous mesh of synthetic material said porous mesh having a porosity to allow oxygen and hormones to pass therethrough; disposing microcapsules between said outer material and said inner tubular mesh, said microcapsules being made of a semi-permeable material and containing hormone-producing cells; and introducing into said prosthesis a spindle of plastic material sized to be introduced into said prosthesis.
Claim 2
Dependent Claim 81 words
A process for the preparation of a vascular prosthesis comprising: forming an outer material having a low porosity and an inner tubular porous mesh of synthetic material said porous mesh having a porosity to allow oxygen and hormones to pass therethrough; disposing microcapsules between said outer material and said inner tubular mesh, said microcapsules being made of a semi-permeable material and containing hormone-producing cells; and introducing into said prosthesis a spindle of plastic material sized to be introduced into said prosthesis.
Claim 3
Dependent Claim 35 words
Process according to claim 1, wherein said spindle is made of a material selected from the group consisting of silastic and PVC and has an external diameter compatible with the internal diameter of said mesh.
Claim 4
Dependent Claim 23 words
Process according to claim 1, wherein said mesh is made up of fibers selected from the group consisting of polyester and polytetrafluoroethylene fibers.
Claim 5
Dependent Claim 19 words
Process according to claim 1, wherein said tubular mesh has an internal diameter of between 4 and 14 mm.
Claim 6
Dependent Claim 21 words
Process according to claim 1, wherein free spaces between filaments making up said mesh are of between 10 and 300 microns.

References Cited (Backward Citations)

US4409331A Cited
US4309776A Cited
EP0188309A2 Cited
EP0393788A2 Cited
US5104403A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-04-12 1996-10-12 1997-04-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-04-12 2000-10-12 2001-04-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-04-12 2004-10-12 2005-04-13 $7700.00 Window Closed / Lapsed

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