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US6712845B2 Expired / Lapsed US ⏱️ 0.0 years remaining

Coating for a stent and a method of forming the same

Assignee: Abbott Cardiovascular Systems Inc
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Filing: 2001-04-24
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Granted: 2004-03-30
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Expires: 2021-04-24
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Abstract

Abstract A coating for a stent and methods for coating a stent are provided. The coating may be used for the sustained delivery of an active ingredient or a combination of active ingredients.

Inventors

  • 👤 Syed Faiyaz Ahmed Hossainy

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:31
CPC Classifications
A; A61; A61L; A61L31/00; A61L31/08; A61L31/10; A61L2400/00; A61L2400/18

Claims Analysis

Total Claims: 51
Claim 1
Independent Claim 79 words
A method of coating a stent, comprising: (a) forming a first layer on a surface of a stent; (b) patterning said first layer to form vias by removing portions of said first layer; (c) forming a second layer to cover the remaining portions of said first layer and to at least partially fill said vias; and (d) removing the remaining portions of said first layer to form a pattern of said second layer on said surface of said stent.
Claim 2
Independent Claim 79 words
A method of coating a stent, comprising: (a) forming a first layer on a surface of a stent; (b) patterning said first layer to form vias by removing portions of said first layer; (c) forming a second layer to cover the remaining portions of said first layer and to at least partially fill said vias; and (d) removing the remaining portions of said first layer to form a pattern of said second layer on said surface of said stent.
Claim 3
Dependent Claim 13 words
A coated stent produced in accordance with the method of claim 1 .
Claim 4
Dependent Claim 20 words
The method of claim 1 , additionally comprising forming a third layer on the remaining portions of said second layer.
Claim 5
Dependent Claim 27 words
The method of claim 3 , wherein said second layer contains a first substance and said third layer contains a second substance different than said first substance.
Claim 6
Dependent Claim 25 words
The method of claim 4 , wherein said first or second substances are selected from a group of therapeutic agents, radiopaque elements and radioactive isotopes.
Claim 7
Dependent Claim 29 words
The method of claim 3 , wherein said second layer comprises a therapeutic agent and said third layer is configured to be a diffusion barrier for said therapeutic agent.
Claim 8
Dependent Claim 13 words
The method of claim 1 , wherein said first layer comprises a polymer.
Claim 9
Dependent Claim 25 words
The method of claim 7 , wherein said polymer has a coefficient of extinction k equal to or greater than 1×10 4 cm −1 .
Claim 10
Dependent Claim 24 words
The method of claim 1 , wherein said first layer comprises a polymer selected from the group consisting of polyimide, segmented polyurethane and polycarbonate.
Claim 11
Dependent Claim 23 words
The method of claim 1 , wherein patterning said first layer to form vias comprises directing a laser discharge to said first layer.
Claim 12
Dependent Claim 20 words
The method of claim 1 , wherein said vias have a width of about 5 microns to about 500 microns.
Claim 13
Dependent Claim 18 words
The method of claim 1 , wherein said second layer comprises a polymer and optionally a therapeutic agent.
Claim 14
Independent Claim 106 words
A method of coating a stent, comprising: (a) forming a primer layer on a surface of a stent substrate; (b) forming a first layer on said primer layer; (c) patterning said first layer to form vias in said first layer, wherein said primer layer remains essentially undisturbed on the surface of said stent substrate; (d) forming a second layer on the remaining portions of said first layer and in said vias on said primer layer; and (e) removing the remaining portions of said first layer to remove portions of said second layer disposed on the remaining portions of said first layer to pattern said second layer.
Claim 15
Independent Claim 106 words
A method of coating a stent, comprising: (a) forming a primer layer on a surface of a stent substrate; (b) forming a first layer on said primer layer; (c) patterning said first layer to form vias in said first layer, wherein said primer layer remains essentially undisturbed on the surface of said stent substrate; (d) forming a second layer on the remaining portions of said first layer and in said vias on said primer layer; and (e) removing the remaining portions of said first layer to remove portions of said second layer disposed on the remaining portions of said first layer to pattern said second layer.
Claim 16
Dependent Claim 17 words
The method of claim 13 , wherein said primer layer or said first layer comprises a polymer.
Claim 17
Dependent Claim 25 words
The method of claim 14 , wherein said polymer has a coefficient of extinction k equal to or greater than 1×10 4 cm −1 .
Claim 18
Dependent Claim 24 words
The method of claim 13 , wherein said first layer comprises a polymer selected from the group consisting of polyimide, segmented polyurethane and polycarbonate.
Claim 19
Dependent Claim 23 words
The method of claim 13 , wherein patterning said first layer to form vias comprises directing a laser discharge to said first layer.
Claim 20
Dependent Claim 20 words
The method of claim 13 , wherein said vias have a width of about 5 microns to about 500 microns.
Claim 21
Dependent Claim 18 words
The method of claim 13 , wherein said second layer comprises a polymer and optionally a therapeutic agent.
Claim 22
Independent Claim 95 words
A method of coating a stent, comprising: (a) forming a first layer on the surface of a stent; (b) patterning said first layer to expose portions of the surface of said stent; (c) forming depots in said stent between the remaining portions of said first layer; (d) forming a second layer on said stent, wherein said second layer fills said depots; and (e) removing the remaining portions of said first layer to remove portions of said second layer disposed on the remaining portions of said first layer, wherein said second layer remains in said depots.
Claim 23
Independent Claim 95 words
A method of coating a stent, comprising: (a) forming a first layer on the surface of a stent; (b) patterning said first layer to expose portions of the surface of said stent; (c) forming depots in said stent between the remaining portions of said first layer; (d) forming a second layer on said stent, wherein said second layer fills said depots; and (e) removing the remaining portions of said first layer to remove portions of said second layer disposed on the remaining portions of said first layer, wherein said second layer remains in said depots.
Claim 24
Dependent Claim 27 words
The method of claim 20 , additionally comprising reducing the profile of said second layer such that said second layer does not protrude out from said depots.
Claim 25
Dependent Claim 23 words
The method of claim 20 , additionally comprising forming a third layer over said second layer and on the surface of said stent.
Claim 26
Dependent Claim 29 words
The method of claim 22 , wherein said second layer comprises a therapeutic agent and said third layer is configured to be a diffusion barrier for said therapeutic agent.
Claim 27
Dependent Claim 27 words
The method of claim 22 , wherein said second layer contains a first substance and said third layer contains a second substance different from said first substance.
Claim 28
Dependent Claim 13 words
The method of claim 20 , wherein said first layer comprises a polymer.
Claim 29
Dependent Claim 25 words
The method of claim 20 , wherein said polymer has a coefficient of extinction k equal to or greater than 1×10 4 cm −1 .
Claim 30
Dependent Claim 24 words
The method of claim 20 , wherein said first layer comprises a polymer selected from the group consisting of polyimide, segmented polyurethane and polycarbonate.
Claim 31
Dependent Claim 20 words
The method of claim 20 , wherein patterning said first layer comprises directing a laser discharge to said first layer.
Claim 32
Dependent Claim 18 words
The method of claim 20 , wherein said second layer comprises a polymer and optionally a therapeutic agent.
Claim 33
Dependent Claim 23 words
The method of claim 20 , wherein forming depots in said stent comprises directing a laser discharge to the surface of said stent.
Claim 34
Independent Claim 86 words
A method of coating a stent, comprising: (a) forming a first layer on a stent; (b) forming a second layer on said first layer; (c) patterning said second layer to form vias in said second layer to expose portions of said first layer; (d) removing the exposed portions of said first layer, wherein portions of said first layer positioned underneath the remaining portions of said second layer remain essentially undisturbed; and (e) removing the remaining portions of said second layer to form a patterned first layer.
Claim 35
Independent Claim 86 words
A method of coating a stent, comprising: (a) forming a first layer on a stent; (b) forming a second layer on said first layer; (c) patterning said second layer to form vias in said second layer to expose portions of said first layer; (d) removing the exposed portions of said first layer, wherein portions of said first layer positioned underneath the remaining portions of said second layer remain essentially undisturbed; and (e) removing the remaining portions of said second layer to form a patterned first layer.
Claim 36
Dependent Claim 20 words
The method of claim 31 , additionally comprising forming a third layer on the remaining portions of said first layer.
Claim 37
Dependent Claim 30 words
The method of claim 32 , additionally comprising reducing the profile of said third layer so as to create an alternating pattern of said first layer and said third layer.
Claim 38
Dependent Claim 27 words
The method of claim 32 , wherein said first layer contains a first substance and said third layer contains a second substance different from said first substance.
Claim 39
Dependent Claim 16 words
The method of claim 34 , wherein the said first and second substances are therapeutic agents.
Claim 40
Dependent Claim 19 words
The method of claim 32 , wherein said first layer is a discontinuous layer interrupted by said third layer.
Claim 41
Dependent Claim 29 words
The method of claim 32 , wherein said first layer comprises a therapeutic agent and said third layer is configured to be a diffusion barrier for said therapeutic agent.
Claim 42
Dependent Claim 13 words
The method of claim 31 , wherein said second layer comprises a polymer.
Claim 43
Dependent Claim 25 words
The method of claim 38 , wherein said polymer has a coefficient of extinction k equal to or greater than 1×10 4 cm −1 .
Claim 44
Dependent Claim 14 words
The method of claim 31 , wherein said second layer comprises polyurethane or parylene.
Claim 45
Dependent Claim 23 words
The method of claim 31 , wherein patterning said second layer to form vias comprises directing a laser discharge to said second layer.
Claim 46
Dependent Claim 20 words
The method of claim 31 , wherein said vias have a width of about 5 microns to about 500 microns.
Claim 47
Dependent Claim 18 words
The method of claim 31 , wherein said first layer comprises a polymer and optionally a therapeutic agent.
Claim 48
Independent Claim 76 words
A method of coating a stent, comprising: (a) forming a primer layer on a surface of a stent substrate; (b) forming a first layer on said primer layer; (c) patterning said first layer to form vias in said first layer, wherein said primer layer remains essentially undisturbed on the surface of said stent substrate; and (d) forming a second layer on the remaining portions of said first layer and in said vias on said primer layer.
Claim 49
Independent Claim 76 words
A method of coating a stent, comprising: (a) forming a primer layer on a surface of a stent substrate; (b) forming a first layer on said primer layer; (c) patterning said first layer to form vias in said first layer, wherein said primer layer remains essentially undisturbed on the surface of said stent substrate; and (d) forming a second layer on the remaining portions of said first layer and in said vias on said primer layer.
Claim 50
Independent Claim 90 words
A method of coating an implantable medical device, comprising: (a) forming a first layer on an implantable medical device; (b) forming a second layer on said first layer; (c) patterning said second layer to form vias in said second layer to expose portions of said first layer; (d) removing the exposed portions of said first layer, wherein portions of said first layer positioned underneath the remaining portions of said second layer remain essentially undisturbed; and (e) removing the remaining portions of said second layer to form a patterned first layer.
Claim 51
Independent Claim 90 words
A method of coating an implantable medical device, comprising: (a) forming a first layer on an implantable medical device; (b) forming a second layer on said first layer; (c) patterning said second layer to form vias in said second layer to expose portions of said first layer; (d) removing the exposed portions of said first layer, wherein portions of said first layer positioned underneath the remaining portions of said second layer remain essentially undisturbed; and (e) removing the remaining portions of said second layer to form a patterned first layer.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2007-03-30 2007-09-29 2008-03-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2011-03-30 2011-09-29 2012-03-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2015-03-30 2015-09-29 2016-03-30 $7700.00 Window Closed / Lapsed

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