US5695857A
Expired / Lapsed
US
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Actively sterile surfaces
Assignee: 749110 ALBERTA Ltd
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Filing: 1991-12-23
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Granted: 1997-12-09
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Expires: 2011-12-23
Abstract
Abstract PCT No. PCT/CA91/00453 Sec. 371 Date Aug. 23, 1993 Sec. 102(e) Date Aug. 23, 1993 PCT Filed Dec. 23, 1991 PCT Pub. No. WO92/11043 PCT Pub. Date Jul. 9, 1992An actively antimicrobial surface for a substrate and for use in a biologically dynamic environment, such as for treating and preventing microbial infections, comprises a film consisting of at least an antimicrobial element and another electrochemically nobler element and which forms multitudinous galvanic cells with electrolyte containing biological fluids, such as body fluids from wounds, etc., for releasing the antimicrobial element at the surface.
Inventors
- 👤 Robert Edward Burrell
- 👤 Aron Marcus Rosenfeld
- 👤 Timothy J. N. Smith
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 17:11
CPC Classifications
A; A61; A61L; A61L2/00; A61L2/16; A61L2/23; A61L2/232; A61F; A61F2/00; A61F2/0077; A61L15/00; A61L15/16; A61L15/42; A61L15/46; A61L2/238; A61L27/00; A61L27/50; A61L27/54; A61L29/00; A61L29/14; A61L29/16; A61L31/00; A61L31/14; A61L31/16; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/10; A61L2300/102; A61L2300/40; A61L2300/404; A61L2300/60; A61L2300/606; A61L2300/608; Y; Y10; Y10S; Y10S604/00; Y10S604/905; Y10T; Y10T428/00; Y10T428/24; Y10T428/24802; Y10T428/24917; Y10T428/31504; Y10T428/31678; Y10T428/31681; Y10T428/31692
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
135 words
On a substrate for use with biological fluids, an actively antimicrobial surface film, comprising: at least a pair of superimposed layers on the substrate, the layers of each pair being in electrical contact with each other, one of the layers in each pair being formed from a first element, the other of the layers in each pair being formed from a second element different from the first element, the second element being electrochemically nobler than the first element, at least the first element being an antimicrobially active metal element, each of the layers not in contact with the substrate being substantially discontinuous such that the layer below is exposed, whereby the first element releases ions of the antimicrobially active metal element when a biological fluid is brought into contact with the actively antimicrobial surface film.
Claim 2
Dependent Claim
135 words
On a substrate for use with biological fluids, an actively antimicrobial surface film, comprising: at least a pair of superimposed layers on the substrate, the layers of each pair being in electrical contact with each other, one of the layers in each pair being formed from a first element, the other of the layers in each pair being formed from a second element different from the first element, the second element being electrochemically nobler than the first element, at least the first element being an antimicrobially active metal element, each of the layers not in contact with the substrate being substantially discontinuous such that the layer below is exposed, whereby the first element releases ions of the antimicrobially active metal element when a biological fluid is brought into contact with the actively antimicrobial surface film.
Claim 3
Dependent Claim
29 words
The actively antimicrobial surface film as defined in claim 1, wherein the antimicrobially active metal element is one or more of platinum, gold, silver, zinc, tin, antimony and bismuth.
Claim 4
Dependent Claim
35 words
The actively antimicrobial surface film as defined in claim 2, wherein the second element is electrochemically nobler than the first element and is one or more of platinum, osmium, iridium, palladium, gold, silver and carbon.
Claim 5
Dependent Claim
26 words
The actively antimicrobial surface film as defined in claim 1, wherein at least one of the layers in each pair is formed from a metal alloy.
Claim 6
Dependent Claim
29 words
The actively antimicrobial surface film as defined in claim 1, which comprises at least two pairs of the layers formed from alternating layers of the first and second elements.
Claim 7
Dependent Claim
25 words
The actively antimicrobial surface film as defined in claim 1, wherein one of the layers in each pair is formed from copper, silver and iodine.
Claim 8
Dependent Claim
25 words
The actively antimicrobial surface film as defined in claim 5, wherein one of the layers in each pair is formed from copper, silver and iodine.
Claim 9
Dependent Claim
23 words
The actively antimicrobial surface film as defined in claim 5, wherein the layers in each pair have a thickness of about 1000 A.
Claim 10
Dependent Claim
46 words
The actively antimicrobial surface film as defined in claim 1, wherein the layers form a plurality of spicules, each spicule being formed from alternating layers of the first and second elements, each of the layers being in contact with the layer on which it is superimposed.
Claim 11
Dependent Claim
46 words
The actively antimicrobial surface film as defined in claim 5, wherein the layers form a plurality of spicules, each spicule being formed from alternating layers of the first and second elements, each of the layers being in contact with the layer on which it is superimposed.
Claim 12
Dependent Claim
41 words
The actively antimicrobial surface film as defined in claim 9, which further comprises a partial coating on the spicules, the partial coating being formed by shadow deposition from a third element which is electrochemically nobler than the first and second elements.
Claim 13
Dependent Claim
28 words
The actively antimicrobial surface film as defined in claim 1, wherein the discontinuity in the layers not in contact with the substrate is formed by texturing the layers.
Claim 14
Dependent Claim
30 words
The actively antimicrobial surface film as defined in claim 5, wherein the discontinuity in the layer of each pair most distant from the substrate is formed by texturing the layer.
Claim 15
Dependent Claim
160 words
A process for the production of an actively antimicrobial surface film on a substrate for use with electrolytes containing biological fluids, comprising the steps of: forming a first layer comprising one of a first element or a second element on a surface of the substrate; forming a second layer on the first layer, comprising the other of the first element or the second element of the first layer; and texturing at least the second layer to expose the first layer; wherein at least the first element is an antimicrobially active metal element, the second element being different from, and electrochemically nobler than the first element, and the first and second elements in the first and second layers being in electrical contact with each other, and whereby when a biological fluid is brought into contact with the actively antimicrobial surface film, both the first and second layers are contacted and the first element releases ions of the antimicrobially active metal element.
Claim 16
Dependent Claim
160 words
A process for the production of an actively antimicrobial surface film on a substrate for use with electrolytes containing biological fluids, comprising the steps of: forming a first layer comprising one of a first element or a second element on a surface of the substrate; forming a second layer on the first layer, comprising the other of the first element or the second element of the first layer; and texturing at least the second layer to expose the first layer; wherein at least the first element is an antimicrobially active metal element, the second element being different from, and electrochemically nobler than the first element, and the first and second elements in the first and second layers being in electrical contact with each other, and whereby when a biological fluid is brought into contact with the actively antimicrobial surface film, both the first and second layers are contacted and the first element releases ions of the antimicrobially active metal element.
Claim 17
Dependent Claim
42 words
The process as defined in claim 14, which includes the further steps of forming alternating additional layers of the first and second elements, and texturing each of the layers not in contact with the substrate such that the layer below is exposed.
Claim 18
Dependent Claim
31 words
The process as defined in claim 15, wherein the film has a total thickness of about 1μ and each of the first and second layers have thicknesses of about 1000 A.
Claim 19
Dependent Claim
18 words
The process as defined in claim 14, wherein the first and second layers are formed by vapor deposition.
Claim 20
Dependent Claim
18 words
The process as defined in claim 14, wherein the first and second layers are formed by chemical deposition.
Claim 21
Dependent Claim
18 words
The process as defined in claim 14, wherein the first and second layers are formed by ionic deposition.
Claim 22
Dependent Claim
16 words
The process as defined in claim 14, wherein first and second layers are textured by etching.
Claim 23
Dependent Claim
51 words
The process as defined in claim 14, wherein the antimicrobially active metal element is one or more of platinum, gold, silver, copper, zinc, tin, antimony, and bismuth, and the second element is electrochemically nobler than the antimicrobially active metal element and comprises of platinum, osmium, iridium, palladium, gold, silver and carbon.
References Cited (Backward Citations)
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 2000-12-08 | 2001-06-09 | 2001-12-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-12-08 | 2005-06-09 | 2005-12-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-12-08 | 2009-06-09 | 2009-12-09 | $7700.00 | Window Closed / Lapsed |