EP0970711A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Process for coating stents
Assignee: Ethicon Inc
•
Filing: 1999-06-29
•
Granted: —
•
Expires: 2019-06-29
Abstract
Abstract A process is provided for coating stents having a first and second surface with passages there between to avoid blockage and bridging of the passages. The process comprises contacting the stent with a liquid coating solution containing a film forming biocompatible polymer under conditions suitable to allow the film forming biocompatible polymer to coat at least one surface of the stent while maintaining a fluid flow through said passages sufficient prevent the film forming biocompatible polymer from substantially blocking said passages. Also described are stents coated by this process.
Inventors
- 👤 Syed F.A. Hossainy
- 👤 Mark B. Roller
- 👤 Gerard H. Llanos
- 👤 Gregory A. Kopia
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 22:03
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61L; A61L31/00; A61L31/08; A61L31/10; A61L31/14; A61L31/16; A61L33/00; A61L33/0005; A61L33/0011; A61L33/0047; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/60; A61L2300/606; A61L2420/00; A61L2420/02
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
102 words
A method for coating a stent having an outer surface and inner surface with
passages between the outer and inner surfaces comprising: (a) contacting the stent with a liquid coating solution containing a film forming
biocompatible polymer under conditions suitable to allow the film forming biocompatible
polymer to coat at least one surface of the stent; (b) before the coating solution dries creating fluid movement out of the passages of the
stent sufficient to prevent the film forming biocompatible polymer from substantially
blocking said passages thereafter; (c) drying the stent to provide at least a partially coated stent with a first coating.
Claim 2
Dependent Claim
32 words
The method of claim 1 wherein the stent is contacted with the coating solution by
dipping the stent into the coating solution or by spraying the coating solution on to the
stent.
Claim 3
Dependent Claim
72 words
The method of claim 1 or claim 2 wherein fluid movement is created: by contacting
a mandrel with the inner surface of the stent and moving the mandrel relative to the stent to
prevent bridges from forming in said passages; or by contacting the outer surface of the
stent with the inner surface of a tube and moving the tube relative to the stent to prevent
bridges from forming in said passages.
Claim 4
Independent Claim
52 words
The method of any of claims 1 to 3 wherein the film forming biocompatible
polymer is an aliphatic polyester, a poly(amino acid), a copoly(ether-ester), a polyalkylene
oxalate, a polyamide, a poly(iminocarbonate), a polyorthoester, a polyoxaester, a
polyamidoester, a polyoxaester containing amido groups, a poly(anhydride), a
polyphosphazene, a biomolecule or a blend thereof.
Claim 5
Dependent Claim
19 words
The method of claim 4 wherein the film forming polymer is a biocompatible
aliphatic polyester, which is preferably elastomeric.
Claim 6
Dependent Claim
66 words
The method of claim 5 wherein the biocompatible aliphatic polyester is an
elastomeric copolymer of ε-caprolactone and glycolide, an elastomeric copolymer of ε-caprolactone
and lactide, an elastomeric copolymer of p-dioxanone and lactide, an
elastomeric copolymer of ε-caprolactone and p-dioxanone, an elastomeric copolymer of p-dioxanone
and trimethylene carbonate, an elastomeric copolymer of trimethylene carbonate
and glycolide, an elastomeric copolymer of trimethylene carbonate and lactide or blend
thereof.
Claim 7
Independent Claim
22 words
The method of any one of claims 1 to 6 wherein additionally contained in the
coating solution is a pharmaceutically active compound.
Claim 8
Dependent Claim
65 words
The method of claim 7 wherein the pharmaceutically active compound is: an
antiproliferative/antimitotic agent; an antibiotic; an enzyme; an antiproliferative/antimitotic
alkylating agent; an antiproliferative/antimitotic antimetabolite; a hormone; an anticoaglant;
a fibrinolytic agent; an antiplatelet agent; an antimigratory agent; an antisecretory agent; an
antiinflammatory agent; an immunosuppressive agent; an angiogenic agent; a nitric oxide
donor; an anti-sense oligonucleotide or a combination thereof, and is preferably rapamycin.
Claim 9
Independent Claim
18 words
The method of any one of claims 1 to 8, wherein additionally present is a
biocompatble hydrophilic polymer.
Claim 10
Independent Claim
21 words
The method of any one of claims 1 to 9 wherein after the stent is dried a second
coating is applied.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.