US5916882A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Povidone iodine (PVP-I) alcohol gel antimicrobial pre-operative skin preparation
Assignee: CareFusion 2200 Inc
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Filing: 1997-04-08
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Granted: 1999-06-29
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Expires: 2017-04-08
Abstract
Abstract The present invention provides antimicrobial skin-preparations useable to disinfect a surgical site for surgery. The antimicrobial skin-preparation formula includes iodine, alcohol and gel. The new pre-operative skin-preparation quickly and effectively kills microorganisms when applied to the surgical site. The skin-preparation continues to effectively inhibit microorganism growth in the applied area over an extended period of time. One gel skin-preparation according to the invention includes alcohol at 60%-90% v/v, iodine at 1.0%-15.0% w/v, and gel at 0.1%-30.0% w/v. A carrier solvent and other optional components may also be added to the formula.
Inventors
- 👤 David K. Jeng
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 02:27
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A01; A01N; A01N59/00; A01N59/12; A61K31/00; A61K31/74; A61K31/785; A61K31/787; A61K31/79; A61K47/00; A61K47/30; A61K47/36; A61K47/38
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
41 words
An antimicrobial formulation comprising: alcohol from about 60.0% v/v to about 90.0% v/v of the formulation; iodine from about 1.0% w/v to about 15.0% w/v of the formulation; and gel from about 0.1% w/v to about 20.0% w/v of the formulation.
Claim 2
Dependent Claim
41 words
An antimicrobial formulation comprising: alcohol from about 60.0% v/v to about 90.0% v/v of the formulation; iodine from about 1.0% w/v to about 15.0% w/v of the formulation; and gel from about 0.1% w/v to about 20.0% w/v of the formulation.
Claim 3
Dependent Claim
27 words
The antimicrobial formulation of claim 1 wherein the alcohol is selected from the group consisting of ethyl alcohol, methyl alcohol, isopropyl alcohol, butyl alcohol and propyl alcohol.
Claim 4
Dependent Claim
12 words
The antimicrobial formulation of claim 1 wherein the iodine is povidone iodine.
Claim 5
Dependent Claim
14 words
The antimicrobial formulation of claim 1 wherein the gel is a water soluble gel.
Claim 6
Dependent Claim
16 words
The antimicrobial formulation of claim 1 wherein the alcohol is about 62% v/v of the formulation.
Claim 7
Dependent Claim
16 words
The antimicrobial formulation of claim 1 wherein the iodine is about 5% w/v of the formulation.
Claim 8
Dependent Claim
16 words
The antimicrobial formulation of claim 1 wherein the gel is about 7.5% w/v of the formulation.
Claim 9
Dependent Claim
34 words
The antimicrobial formulation of claim 1 wherein the gel simethicone from about 0.1% w/v to about 20% w/v of the formulation; and hydroxypropylcellulose from about 0.1% w/v to about 30% w/v of the formulations.
Claim 10
Dependent Claim
23 words
The antimicrobial formulation of claim 1 further comprising a base pH adjuster from about 0.01% w/v to about 2% w/v of the formulation.
Claim 11
Dependent Claim
16 words
The antimicrobial formulation of claim 9 wherein the base pH adjuster is an alkali metal hydroxide.
Claim 12
Dependent Claim
23 words
The antimicrobial formulation of claim 1 further comprising an acid pH adjuster from about 0.01% w/v to about 5% w/v of the formulation.
Claim 13
Dependent Claim
23 words
The antimicrobial formulation of claim 1 further comprising a skin irritation reducer from about 0.1% w/v to about 5% w/v of the formulation.
Claim 14
Dependent Claim
28 words
The antimicrobial formulation of claim 12 wherein the skin irritation reducer is selected from the group consisting of glycerin, petroleum jelly, petrolatum, mineral oil, ethylene glycol and glycerol.
Claim 15
Dependent Claim
43 words
An antimicrobial formulation comprising: ethyl alcohol from about 60.0% v/v to about 90.0% v/v of the formulation; povidone iodine from about 1.0% w/v to about 15.0% w/v of the formulation; and gel from about 0.1% w/v to about 20.0% w/v of the formulation.
Claim 16
Dependent Claim
43 words
An antimicrobial formulation comprising: ethyl alcohol from about 60.0% v/v to about 90.0% v/v of the formulation; povidone iodine from about 1.0% w/v to about 15.0% w/v of the formulation; and gel from about 0.1% w/v to about 20.0% w/v of the formulation.
Claim 17
Dependent Claim
54 words
The antimicrobial formulation of claim 14 further comprising: a base pH adjuster from about 0.01% w/v to about 2% w/v of the formulation; an acid pH adjuster from about 0.01% w/v to about 5% w/v of the formulation; and a skin irritation reducer from about 0.1% w/v to about 5% w/v of the formulation.
Claim 18
Dependent Claim
31 words
An antimicrobial formulation comprising: ethyl alcohol at about 62.0% v/v of the formulation; povidone iodine at about 5.0% w/v of the formulation; and gel at about 7.5% w/v of the formulation.
Claim 19
Dependent Claim
31 words
An antimicrobial formulation comprising: ethyl alcohol at about 62.0% v/v of the formulation; povidone iodine at about 5.0% w/v of the formulation; and gel at about 7.5% w/v of the formulation.
Claim 20
Dependent Claim
35 words
The antimicrobial formulation of claim 16 further comprising: sodium hydroxide at about 0.2% w/v of the formulation; citric acid at about 0.5% w/v of the formulation; and glycerin at about 1.0% w/v of the formulation.
Claim 21
Independent Claim
84 words
A method of applying a pre-operative skin preparation to a patient comprising the steps of: a) providing a skin-preparation formulation comprising: alcohol from about 60.0% v/v to about 90.0% v/v of the formulation; iodine from about 1.0% w/v to about 15.0 w/v of the formulation; and gel from about 0.1% w/v to about 20.0% w/v of the formulation; b) applying the skin-preparation formulation to a surgical site on the patient; and c) removing any excess amount of the skin-preparation formulation from the surgical site.
Claim 22
Independent Claim
84 words
A method of applying a pre-operative skin preparation to a patient comprising the steps of: a) providing a skin-preparation formulation comprising: alcohol from about 60.0% v/v to about 90.0% v/v of the formulation; iodine from about 1.0% w/v to about 15.0 w/v of the formulation; and gel from about 0.1% w/v to about 20.0% w/v of the formulation; b) applying the skin-preparation formulation to a surgical site on the patient; and c) removing any excess amount of the skin-preparation formulation from the surgical site.
Claim 23
Dependent Claim
29 words
The method of claim 18 wherein step b) comprises the step of scrubbing the surgical site with the skin-preparation formulation for approximately a 30 second maximum length of time.
Claim 24
Dependent Claim
56 words
The method of claim 18 wherein step a) comprises the step of providing the skin-preparation formulation comprising ethyl alcohol from about 60.0% v/v to about 90.0% v/v of the formulation; povidone iodine from about 1.0% w/v to about 15.0 w/v of the formulation; and gel from about 0.1% w/v to about 20.0% w/v of the formulation.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 2002-06-28 | 2002-12-28 | 2003-06-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-06-28 | 2006-12-28 | 2007-06-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-06-28 | 2010-12-28 | 2011-06-29 | $7700.00 | Window Closed / Lapsed |