US5137718A
Expired / Lapsed
US
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Infection fighting composition for topical application
Assignee: G&S MEDIAL Ltd
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Filing: 1990-05-15
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Granted: 1992-08-11
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Expires: 2010-05-15
Abstract
Abstract A composition for a topically applied therapeutic cream or ointment having effective activity against one or a combination of sources of viral, bacterial, yeast and fungus infections characterized by the ability to penetrate beneath the epidermal layer of the skin. The composition includes a water soluble active component which is formulated with a water soluble organic solid base and a water soluble surfactant to form an aqueous solution having a gel-like consistency. A preferred active ingredient is a povidone-iodine complex. A preferred carrier is hydroxyethylcellulose.
Inventors
- 👤 C. Edward Gillespie
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 02:07
CPC Classifications
A; A61; A61K; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K31/00; A61K31/74; A61K31/785; A61K31/787; A61K31/79; A61K47/30; A61K47/36; A61K47/38; A61K47/50; A61K47/51; A61K47/56; A61K47/58; A61K9/00; A61K9/0012; A61K9/0014
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
135 words
An improved topically applied therapeutic agent comprising, in combination; a) a povidone-iodine complex and hydroxyethylcellulose in a weight percent ratio greater than 3 parts of a povidone-iodine complex to each part of hydroxyethylcellulose to provide an effective therapeutic amount of iodine for topical applications; b) a water soluble surfactant in an amount effective to aid penetration of the composition through the pores of the epidermal layer of a human; c) an emollient in an amount effective to reduce the irritating effect of iodine on healthy human tissue; and d) water in an amount effective to form a homogeneous solution of the components in (a), (b) and (c) having a gel-like consistency which does not result in stratification into separate layers and a viscosity in a range between 8000 to 15,000 cps at 25 degrees C.
Claim 2
Dependent Claim
135 words
An improved topically applied therapeutic agent comprising, in combination; a) a povidone-iodine complex and hydroxyethylcellulose in a weight percent ratio greater than 3 parts of a povidone-iodine complex to each part of hydroxyethylcellulose to provide an effective therapeutic amount of iodine for topical applications; b) a water soluble surfactant in an amount effective to aid penetration of the composition through the pores of the epidermal layer of a human; c) an emollient in an amount effective to reduce the irritating effect of iodine on healthy human tissue; and d) water in an amount effective to form a homogeneous solution of the components in (a), (b) and (c) having a gel-like consistency which does not result in stratification into separate layers and a viscosity in a range between 8000 to 15,000 cps at 25 degrees C.
Claim 3
Dependent Claim
22 words
The composition defined in claim 1 having the ability to penetrate through the pores of the human epidermis layer upon topical application.
Claim 4
Dependent Claim
26 words
The composition defined in claim 2 wherein said weight percent ratio between the povidone-iodine complex and the hydroxyethylcellulose is at least 6 to 1 or greater.
Claim 5
Independent Claim
128 words
A method of making a water soluble topical ointment therapeutically effective against one or a combination of sources of viral, bacterial, yeast or fungus infections, comprising the steps of: a) forming an aqueous solution containing a selected amount of a povidone-iodine complex in a selected amount of water; b) adding a water-soluble emollient to the solution formed in step (a); c) adding an amount of hydroxyethylcellulose to said solution containing the components in (a), (b) and (c) effective to form a gel-like consistency which does not result in stratification into separate layers and which has a viscosity between about 8000 to 15,000 cps at 25 degrees C., wherein the weight percent ratio of said povidone-iodine complex to said amount of hydroxyethylcellulose added is greater than 3 to 1.
Claim 6
Independent Claim
128 words
A method of making a water soluble topical ointment therapeutically effective against one or a combination of sources of viral, bacterial, yeast or fungus infections, comprising the steps of: a) forming an aqueous solution containing a selected amount of a povidone-iodine complex in a selected amount of water; b) adding a water-soluble emollient to the solution formed in step (a); c) adding an amount of hydroxyethylcellulose to said solution containing the components in (a), (b) and (c) effective to form a gel-like consistency which does not result in stratification into separate layers and which has a viscosity between about 8000 to 15,000 cps at 25 degrees C., wherein the weight percent ratio of said povidone-iodine complex to said amount of hydroxyethylcellulose added is greater than 3 to 1.
Claim 7
Dependent Claim
24 words
The method defined in claim 4 wherein said weight percent ratio of said povidone-iodine complex to said hydroxyethylcellulose is at least 6 to 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-08-11 | 1996-02-10 | 1996-08-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-08-11 | 2000-02-10 | 2000-08-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-08-11 | 2004-02-10 | 2004-08-11 | $7700.00 | Window Closed / Lapsed |