US5071648A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polymeric broad-spectrum antimicrobial materials
Assignee: Medtronic Xomed LLC
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Filing: 1990-03-29
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Granted: 1991-12-10
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Expires: 2010-03-29
Abstract
Abstract A sustained and controlled release form of iodine is achieved by a complex of polyvinyl alcohol and the iodine characterized by a low water solubility. The polyvinyl alcohol may be reacted to form hydroxylated polyvinyl acetal sponge and the sponge is topically applied as an antimicrobial agent which releases controlled amounts of iodine sufficient to kill germ cells with minimal toxicity to surrounding tissue.
Inventors
- 👤 Solomon Rosenblatt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 15:34
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/16; A61L15/18; A01; A01N; A01N59/00; A01N59/12; A01N59/14
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
23 words
A composition comprising acetalized polyvinyl alcohol complexed with iodine, wherein said composition is capable of releasing free iodine in the presence of water.
Claim 2
Dependent Claim
23 words
A composition comprising acetalized polyvinyl alcohol complexed with iodine, wherein said composition is capable of releasing free iodine in the presence of water.
Claim 3
Dependent Claim
16 words
The composition of claim 1 wherein said acetalized polyvinyl alcohol is a hydroxylated polyvinyl acetal sponge.
Claim 4
Dependent Claim
16 words
The composition of claim 1 wherein said acetalized polyvinyl alcohol is further complexed with a borate.
Claim 5
Dependent Claim
14 words
The composition of claim 1 wherein said composition is a sponge, foam or gel.
Claim 6
Dependent Claim
29 words
An antimicrobial product which includes a composition comprising acetalized polyvinyl alcohol complexed with iodine, wherein said composition is capable of releasing free iodine ions in the presence of water.
Claim 7
Dependent Claim
29 words
An antimicrobial product which includes a composition comprising acetalized polyvinyl alcohol complexed with iodine, wherein said composition is capable of releasing free iodine ions in the presence of water.
Claim 8
Dependent Claim
29 words
The product of claim 5 wherein said product further comprises a substrate for receiving said film, said substrate being selected from the group consisting of cloth or nonwoven webbing.
Claim 9
Dependent Claim
26 words
The product of claim 6 wherein said product is selected from the group consisting of filters, wound dressings, topical pads, cleansing wipes and odor control shields.
Claim 10
Independent Claim
60 words
A method of controlling infection, said method comprising topical application of a product which includes an antimicrobially effective amount of a controlled-release agent, said agent comprising iodine in complex with a polymer selected from the group consisting of polyvinyl alcohol and acetalized polyvinyl alcohol, and said controlled release agent being capable, in the presence of water, of releasing free iodine.
Claim 11
Independent Claim
60 words
A method of controlling infection, said method comprising topical application of a product which includes an antimicrobially effective amount of a controlled-release agent, said agent comprising iodine in complex with a polymer selected from the group consisting of polyvinyl alcohol and acetalized polyvinyl alcohol, and said controlled release agent being capable, in the presence of water, of releasing free iodine.
Claim 12
Dependent Claim
12 words
The method of claim 8 wherein said product is a wound dressing.
Claim 13
Dependent Claim
20 words
The method of claim 9 wherein said wound dressing changes color as iodine in said controlled release agent is depleted.
Claim 14
Dependent Claim
14 words
The method of claim 8 wherein said polymer is further complexed with a borate.
References Cited (Backward Citations)
US1867222A
Cited
US2381621A
Cited
US3328259A
Cited
US4031209A
Cited
US4128633A
Cited
US4675009A
Cited
US4340043A
Cited
US4255415A
Cited
US4323557A
Cited
US4396642A
Cited
US4552138A
Cited
EP0174108A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-12-09 | 1995-06-10 | 1995-12-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-12-09 | 1999-06-10 | 1999-12-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-12-09 | 2003-06-10 | 2003-12-10 | $7700.00 | Window Closed / Lapsed |