US5098717A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of treatment for pruritus
Assignee: Thames Pharmacal Co Inc
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Filing: 1991-02-19
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Granted: 1992-03-24
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Expires: 2011-02-19
Abstract
Abstract A method of treating a pruritic skin area in a mammal by application to the affected area of a gel composition containing from about 60 to about 90% ethyl alcohol, from about 0.5 to about 30% water, at least one gelling agent and a pharmaceutically effective amount of a topically active, antipruritic, antihistaminic agent. The gel may be applied to the affected area from one to five times daily.
Inventors
- 👤 Steven T. Blackman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 00:42
CPC Classifications
A; A61; A61K; A61K47/00; A61K47/30; A61K47/36; A61K47/38; A61K47/06; A61K47/08; A61K47/10; A61K47/32; A61K9/00; A61K9/0012; A61K9/0014
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
74 words
A method of treating pruritus in an affected skin area of a mammal comprising the application to the skin area of a gel composition including: (a) from about 60 to about 90% by weight ethyl alcohol; (b) from about 0.5 to about 30% by weight water; (c) from about 0.5 to about 5% by weight of at least one gelling agent; and (d) a pharmaceutically effective amount of a topically active, antipruritic, antihistaminic agent.
Claim 2
Independent Claim
74 words
A method of treating pruritus in an affected skin area of a mammal comprising the application to the skin area of a gel composition including: (a) from about 60 to about 90% by weight ethyl alcohol; (b) from about 0.5 to about 30% by weight water; (c) from about 0.5 to about 5% by weight of at least one gelling agent; and (d) a pharmaceutically effective amount of a topically active, antipruritic, antihistaminic agent.
Claim 3
Dependent Claim
15 words
A method according to claim 1 wherein said antihistaminic agent is diphenhydramine or diphenhydramine hydrochloride.
Claim 4
Dependent Claim
13 words
A method according to claim 2 wherein said antihistaminic agent is diphenhydramine hydrochloride.
Claim 5
Dependent Claim
19 words
A method according to claim 1 wherein said composition includes from about 60 to about 80% alcohol by weight.
Claim 6
Dependent Claim
19 words
A method according to claim 1 wherein said composition includes from about 8 to about 30% water by weight.
Claim 7
Dependent Claim
14 words
A method according to claim 1 wherein said gelling agent is a carboxyvinyl polymer.
Claim 8
Dependent Claim
24 words
A method according to claim 1 wherein said composition additionally includes from about 0.2 to about 5% of a gel neutralizing agent by weight.
Claim 9
Dependent Claim
22 words
A method according to claim 7 wherein said gel neutralizing agent is selected from the group consisting of triethanolamine and tetrahydroxypropyl ethylenediamine.
Claim 10
Dependent Claim
21 words
A method according to claim 1 wherein said composition additionally includes from about 0.1 to about 3% gelling enhancer by weight.
Claim 11
Dependent Claim
21 words
A method according to claim 9 wherein said gelling enhancer is selected from the group consisting of hydroxymethyl cellulose and hydroxyethylcellulose.
Claim 12
Dependent Claim
15 words
A method according to claim 1 wherein said composition additionally includes an ultraviolet absorbing ingredient.
Claim 13
Dependent Claim
16 words
A method according to claim 1 wherein said composition additionally includes an emollient or humectant ingredient.
Claim 14
Dependent Claim
15 words
A method according to claim 1 wherein said composition additionally includes a gel clarifying ingredient.
Claim 15
Dependent Claim
20 words
A method according to claim 3 wherein said composition additionally includes about 0.5 to about 3.5% diphenhydramine hydrochloride by weight.
Claim 16
Dependent Claim
20 words
A method according to claim 14 wherein said composition additionally includes about 1 to about 2.5% diphenhydramine hydrochloride by weight.
Claim 17
Dependent Claim
16 words
A method according to claim 15 wherein said composition includes about 2% diphenhydramine hydrochloride by weight.
Claim 18
Dependent Claim
14 words
A method according to claim 4 wherein said composition includes about 60% ethyl alcohol.
Claim 19
Dependent Claim
14 words
A method according to claim 4 wherein said composition includes about 75% ethyl alcohol.
Claim 20
Dependent Claim
22 words
A method according to claim 1 wherein said composition is applied to the skin area from 1 to about 5 times daily.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-03-24 | 1995-09-23 | 1996-03-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-03-24 | 1999-09-23 | 2000-03-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-03-24 | 2003-09-23 | 2004-03-24 | $7700.00 | Window Closed / Lapsed |