US4692328A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biologically useful polymer preparations
Assignee: HOLOMETRIX Inc
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Filing: 1985-09-24
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Granted: 1987-09-08
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Expires: 2005-09-24
Abstract
Abstract Described and claimed are biologically useful crosslinked copolymers of vinyl pyrrolidone and allylamine suitable for various preventative and therapeutic applications to intact or injured skin. Coatings of these copolymers, either preformed or prepared in situ on the skin may deliver medicaments to the skin, may serve as an iontophoretic medium, may provide electrical contact with the body, may regulate or control moisture loss from injured integument. Monolithic devices for the delivery of pharmaceutically active agents within living tissue may be formulated from these copolymers.
Inventors
- 👤 Judith P. Kitchell
- 👤 Stanton R. de Riel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 04:21
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61K9/7007; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/225
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
67 words
A biologically useful polymer preparation prepared by A. mixing a first solution comprising 20-60% (weight per volume) copolymer comprising vinyl pyrrolidone and allylamine in a ratio of 10 parts by weight vinyl pyrrolidone to 0-1 part by weight allylamine with a second solution comprising glutaraldehyde to give a final concentration of 0.04-3.6% (weight per volume) glutaraldehyde; and B. forming a film from the mixture of step A.
Claim 2
Dependent Claim
67 words
A biologically useful polymer preparation prepared by A. mixing a first solution comprising 20-60% (weight per volume) copolymer comprising vinyl pyrrolidone and allylamine in a ratio of 10 parts by weight vinyl pyrrolidone to 0-1 part by weight allylamine with a second solution comprising glutaraldehyde to give a final concentration of 0.04-3.6% (weight per volume) glutaraldehyde; and B. forming a film from the mixture of step A.
Claim 3
Dependent Claim
22 words
A biologically useful polymer preparation according to claim 1 wherein said first solution further comprises 0.05 to 0.1% by weight fumaryl chloride.
Claim 4
Dependent Claim
30 words
A biologically useful polymer preparation according to claim 1, wherein said first solution further includes pharmaceutically active agents which will diffuse from the coating to skin covered by the coating.
Claim 5
Dependent Claim
25 words
A polymer prepartation according to claim 1 for use as an electrically funcitonal electrode, wherein said first solution further includes electrolytes to provide electrical conductivity.
Claim 6
Dependent Claim
35 words
A biologically useful polymer preparation according to claim 1, effective in the regulation of mositure loss from injured or burned skin, wherein the thickness of said film is related to moisture loss from said film.
Claim 7
Dependent Claim
32 words
A polymer preparation according to claim 1 wherein said first solution further includes pharmaceutically active agents which may be delivered from the film through iontophoresis into and through intact or injured skin.
References Cited (Backward Citations)
US3563968A
Cited
US3954960A
Cited
US3954682A
Cited
US3755561A
Cited
US4554155A
Cited
US4057623A
Cited
US4273135A
Cited
US4481167A
Cited
US4500339A
Cited
US4321263A
Cited
US4383529A
Cited
US4482533A
Cited
US4504582A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-09-07 | 1991-03-09 | 1991-09-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-09-07 | 1995-03-09 | 1995-09-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-09-07 | 1999-03-09 | 1999-09-08 | $7700.00 | Window Closed / Lapsed |