US4584192A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Film-forming composition containing an antimicrobial agent and methods of use
Assignee: 3M Co
•
Filing: 1984-06-04
•
Granted: 1986-04-22
•
Expires: 2004-06-04
Abstract
Abstract A film-forming composition containing a broad spectrum antimicrobial as an antimicrobial agent. The composition forms a film which is a substantially fluid-resistant, substantially tack-free, flexible film which adheres to skin and releases the antimicrobial agent to skin. A method of using the film-forming composition is also disclosed.
Inventors
- 👤 John D. Dell
- 👤 Milton H. Andrus, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 22:11
CPC Classifications
A; A61; A61L; A61L26/00; A61L26/0061; A61L26/0066; A01; A01N; A01N25/00; A01N25/24; A61L26/0009; A61L26/0014; A61L2300/00; A61L2300/10; A61L2300/106; A61L2300/40; A61L2300/404
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
211 words
A film-forming composition, comprising: (a) a film-forming copolymer consisting essentially of copolymerized A, B and C monomers as follows: A is a monomeric acrylic or methacrylic acid ester of an alkyl alcohol containing a single hydroxyl, said alcohol having from 2 to about 14 carbon atoms when said A monomer is an acrylic acid ester, and 7 to 18 carbon atoms when said A monomer is a methacrylic acid ester, the amount by weight of A monomer being about 15 to 80% of the total weight of all monomers in the copolymer; B is a monomeric methacrylic acid ester of an alkyl alcohol containing a single hydroxyl, said alcohol having from 1 to 6 carbon atoms, the amount by weight of B monomer being about 20 to 70% of the total weight of all monomers in the copolymer; and C is an N-vinyl lactam, the amount by weight of which being about 1 to 15% of the total weight of all monomers in the copolymer; (b) an effective amount of a broad spectrum antimicrobial agent; said composition being dermatologically-acceptable, and, when applied to skin from a fugitive solvent, being capable of forming a clear, substantially fluid-resistant, substantially tack-free, flexible film which adheres to skin and releases said antimicrobial agent to skin.
Claim 2
Dependent Claim
211 words
A film-forming composition, comprising: (a) a film-forming copolymer consisting essentially of copolymerized A, B and C monomers as follows: A is a monomeric acrylic or methacrylic acid ester of an alkyl alcohol containing a single hydroxyl, said alcohol having from 2 to about 14 carbon atoms when said A monomer is an acrylic acid ester, and 7 to 18 carbon atoms when said A monomer is a methacrylic acid ester, the amount by weight of A monomer being about 15 to 80% of the total weight of all monomers in the copolymer; B is a monomeric methacrylic acid ester of an alkyl alcohol containing a single hydroxyl, said alcohol having from 1 to 6 carbon atoms, the amount by weight of B monomer being about 20 to 70% of the total weight of all monomers in the copolymer; and C is an N-vinyl lactam, the amount by weight of which being about 1 to 15% of the total weight of all monomers in the copolymer; (b) an effective amount of a broad spectrum antimicrobial agent; said composition being dermatologically-acceptable, and, when applied to skin from a fugitive solvent, being capable of forming a clear, substantially fluid-resistant, substantially tack-free, flexible film which adheres to skin and releases said antimicrobial agent to skin.
Claim 3
Dependent Claim
50 words
A film-forming composition according to claim 1, wherein said antimicrobial agent is iodine which forms a complex with said film-forming copolymer via the N-vinyl lactam residues contained therein, the amount by weight of iodine being about 0.1 to 15% of the total weight of said film-forming copolymer and said iodine.
Claim 4
Dependent Claim
42 words
A film-forming composition according to claim 2, wherein said alcohol of said A monomer contains about 4-14 carbon atoms when said A monomer is an acrylic acid ester, and about 10-18 carbon atoms when said A monomer is a methacrylic acid ester.
Claim 5
Dependent Claim
21 words
A film-forming composition according to claim 2, wherein said alcohol of said B monomer contains 1 to about 4 carbon atoms.
Claim 6
Dependent Claim
13 words
A film-forming composition according to claim 2, wherein said C monomer is N-vinylpyrrolidone.
Claim 7
Dependent Claim
25 words
A film-forming composition according to claim 2, wherein said A monomer is selected from the group consisting of n-butyl acrylate, isooctyl acrylate and lauryl methacrylate.
Claim 8
Dependent Claim
14 words
A film-forming composition according to claim 2, wherein said A monomer is isooctyl acrylate.
Claim 9
Dependent Claim
23 words
A film-forming composition according to claim 2, wherein said B monomer is selected from the group consisting of methyl methacrylate and n-butyl methacrylate.
Claim 10
Dependent Claim
14 words
A film-forming composition according to claim 2, wherein said B monomer is methyl methacrylate.
Claim 11
Dependent Claim
31 words
A film-forming composition according to claim 2, wherein the amount by weight of said A monomer is about 40 to 60% of the total weight of all monomers in said copolymer.
Claim 12
Dependent Claim
31 words
A film-forming composition according to claim 2, wherein the amount by weight of said B monomer is about 25 to 50% of the total weight of all monomers in said copolymer.
Claim 13
Dependent Claim
31 words
A film-forming composition according to claim 2, wherein said C monomer is present in an amount by weight of about 5-15% of the total weight of all monomers in said copolymer.
Claim 14
Dependent Claim
31 words
A film-forming composition according to claim 2, wherein said iodine is present in an amount by weight of about 2-12% of the total weight of said film-forming copolymer and said iodine.
Claim 15
Dependent Claim
61 words
A film-forming composition according to claim 13, wherein said alcohol of said A monomer contains about 4-14 carbon atoms when said A monomer is an acrylic acid ester, and about 10-18 carbon atoms when said A monomer is a methacrylic acid ester; said alcohol of said B monomer contains 1 to about 4 carbon atoms; and said C monomer is N-vinylpyrrolidone.
Claim 16
Dependent Claim
55 words
A film-forming composition according to claim 14, wherein said C monomer is present in an amount by weight of about 5-15% of the total weight of all monomers in said copolymer, and said iodine is present in an amount by weight of about 2-12% of the total weight of said film-forming copolymer and said iodine.
Claim 17
Dependent Claim
41 words
A film-forming composition according to claim 15, wherein said A monomer is selected from the group consisting of n-butyl acrylate, isooctyl acrylate and lauryl methacrylate, and said B monomer is selected from the group consisting of methyl methacrylate and n-butyl methacrylate.
Claim 18
Dependent Claim
21 words
A film-forming composition according to claim 15, wherein said A monomer is isooctyl acrylate and said B monomer is methyl methacrylate.
Claim 19
Dependent Claim
59 words
A film-forming composition according to claim 2, further comprising an alcohol selected from the group consisting of ethanol and isopropanol, said film-forming polymer being dissolved in said alcohol, and said alcohol being present in an amount of about 20 to 1000 parts by weight per 10 parts by weight of the total of said film-forming copolymer and said iodine.
Claim 20
Dependent Claim
27 words
A film-forming composition according to claim 2, further comprising an inorganic iodide which functions to increase the stability of the complex of iodine with said film-forming copolymer.
Claim 21
Dependent Claim
17 words
A film-forming composition according to claim 1, wherein said antimicrobial agent is chlorhexidine or a derivative thereof.
Claim 22
Dependent Claim
46 words
A method of promoting asepsis on mammalian skin, comprising the steps of: (a) applying to said skin said composition of claim 1; (b) allowing said composition to dry to form said film, and (c) allowing said film to remain on said skin to promote said asepsis.
Claim 23
Dependent Claim
15 words
A method according to claim 21, wherein said film is subsequently removed using a solvent.
Claim 24
Dependent Claim
30 words
A method according to claim 21, wherein said film is covered during a surgical procedure with a surgical drape comprising a pressure-sensitive adhesive layer which is contacted with said film.
Claim 25
Dependent Claim
17 words
A method according to claim 23, wherein said film is subsequently removed by removing said surgical drape.
Claim 26
Dependent Claim
12 words
A method according to claim 21, wherein said antimicrobial agent is iodine.
Claim 27
Dependent Claim
16 words
A method according to claim 21, wherein said antimicrobial agent is chlorhexidine or a derivative thereof.
References Cited (Backward Citations)
US2804073A
Cited
US3216579A
Cited
US3216983A
Cited
US3621079A
Cited
US3671545A
Cited
US3608070A
Cited
US3907720A
Cited
US3577516A
Cited
US3975350A
Cited
US3932602A
Cited
US3928556A
Cited
DE2557607A1
Cited
US4310509A
Cited
US4323557A
Cited
US4374126A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-04-21 | 1989-10-21 | 1990-04-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-04-21 | 1993-10-21 | 1994-04-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-04-21 | 1997-10-21 | 1998-04-22 | $7700.00 | Window Closed / Lapsed |