US4374126A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Film forming antimicrobial material
Assignee: Deseret Medical Inc
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Filing: 1981-02-23
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Granted: 1983-02-15
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Expires: 2001-02-23
Abstract
Abstract A method and composition for a film forming antimicrobial material for animal skin wherein said film is resistant to body fluids and provides long term protection against microorganisms. The composition comprises an alcohol soluble carboxylated polycrylate wherein is added an antimicrobial agent, a topical adhesion promoter, and a difunctional amide which crosslinks said polymer as said solvent evaporates. The topical film so formed does not interfere with respiratory processes and is inert to blood, urine, gastric acids, perspiration, saline solutions and the like. Once formed, said film will not resolubilize in alcohol or other common sterilants. Said topical film adheres to tissue and is resistant to physical removal and to abrasion. Film longevity is in excess of 2 days. Substantial protection is provided against pathogenic bacteria and fungi often implicated in hospital infections and thus can serve as a presurgical dressing, preparation agent, as well as in post-surgical prophylaxis.
Inventors
- 👤 Nathan F. Cardarelli
- 👤 William H. Evans
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 19:29
CPC Classifications
A; A61; A61L; A61L26/00; A61L26/0061; A61L26/0076; A01; A01N; A01N25/00; A01N25/24; A61K; A61K9/00; A61K9/70; A61K9/7015; A61L26/0009; A61L26/0014; A61L26/0066; A61L2300/00; A61L2300/40; A61L2300/404
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
200 words
An alcohol insoluble, antimicrobial topical coating composition comprising: A. from about 6% to about 13% by weight of said composition of a lower acrylate interpolymer which has the formula: ##STR4## wherein R and R 1 each represents hydrogen and methyl, R 2 represents either methyl, ethyl, propyl or butyl; R 3 represents methyl or ethyl; n represents from 3 to 12 weight percent based on combined weight of x, y and z; x represents from 8 to 25 weight percent based on the combined weight of n and z; y represents from 45 to 89 weight percent based on combined weight of n, x and z; z represents from 0 to 44 weight percent based on the combined weights of n, x and y, the sum of the numerical values of n+x+y+z s always 100 and the groups n, x, y and z are present in the polymer in a heterogeneous relative order; B. from about 1% to about 3% by weight of said composition of urea as a cross linking agent; and C. the remainder comprising an adhesion-promoting material selected from the group consisting of a secondary solvent, an emollient, and mixtures thereof, and at least one antimicrobial agent.
Claim 2
Dependent Claim
200 words
An alcohol insoluble, antimicrobial topical coating composition comprising: A. from about 6% to about 13% by weight of said composition of a lower acrylate interpolymer which has the formula: ##STR4## wherein R and R 1 each represents hydrogen and methyl, R 2 represents either methyl, ethyl, propyl or butyl; R 3 represents methyl or ethyl; n represents from 3 to 12 weight percent based on combined weight of x, y and z; x represents from 8 to 25 weight percent based on the combined weight of n and z; y represents from 45 to 89 weight percent based on combined weight of n, x and z; z represents from 0 to 44 weight percent based on the combined weights of n, x and y, the sum of the numerical values of n+x+y+z s always 100 and the groups n, x, y and z are present in the polymer in a heterogeneous relative order; B. from about 1% to about 3% by weight of said composition of urea as a cross linking agent; and C. the remainder comprising an adhesion-promoting material selected from the group consisting of a secondary solvent, an emollient, and mixtures thereof, and at least one antimicrobial agent.
Claim 3
Dependent Claim
26 words
The composition of claims 1 wherein said acrylate interpolymer comprises a mixture thereof with a lower molecular weight acrylate interpolymer of the same general polymeric structure.
Claim 4
Dependent Claim
27 words
The composition of claim 2 wherein said lower molecular weight acrylate interpolymer is present in an amount of up to about 3% by weight of said composition.
Claim 5
Dependent Claim
14 words
The composition of claim 1 wherein said adhesion promoting material comprises a secondary solvent.
Claim 6
Dependent Claim
14 words
The composition of claims 1 or 4 wherein said secondary solvent comprises ethyl acetate.
Claim 7
Dependent Claim
26 words
The composition of claim 5 wherein said ethyl acetate is present in an amount by weight of said composition, of from about 1% to about 2%.
Claim 8
Dependent Claim
11 words
The composition of claim 1 wherein said emollient comprises isopropyl myristate.
Claim 9
Dependent Claim
25 words
The composition of claim 7 wherein said emollient is present in an amount by weight of said composition of from about 1% to about 2%.
Claim 10
Dependent Claim
26 words
The composition of claim 1 wherein said antimicrobial is selected from the group consisting of antibacterial agents, antiseptic agents, antifungal agents, anti-infective agents, and antibiotic agents.
Claim 11
Dependent Claim
11 words
The composition of claim 1 in the form of a spray.
Claim 12
Dependent Claim
11 words
The composition of claim 1 in the form of an ointment.
Claim 13
Dependent Claim
12 words
The composition of claim 1 in the form of a wetted dressing.
Claim 14
Dependent Claim
11 words
The composition of claim 1 in the form of a lotion.
Claim 15
Dependent Claim
11 words
the composition of claim 1 in the form of a cream.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-02-14 | 1986-08-16 | 1987-02-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-02-14 | 1990-08-16 | 1991-02-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-02-14 | 1994-08-16 | 1995-02-15 | $7700.00 | Window Closed / Lapsed |