US5324447A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and activator compositions to disinfect lenses
Assignee: Johnson and Johnson Surgical Vision Inc
•
Filing: 1992-06-30
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Granted: 1994-06-28
•
Expires: 2012-06-30
Abstract
Abstract Methods for disinfecting a lens is disclosed. The methods comprise contacting a lens to be disinfected in a liquid medium with at least one chlorine dioxide precursor in the presence of at least one activator component selected from organic acid anhydrides, oxygen-releasing components and mixtures thereof to effect formation of chlorine dioxide from the chlorine dioxide precursor, thereby disinfecting the lens. Compositions useful in the above-noted methods are also disclosed.
Inventors
- 👤 Sam W. Lam
- 👤 Paul S. Ripley
- 👤 J. Abraham M. Espiritu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 21:04
CPC Classifications
A; A01; A01N; A01N59/00; A61; A61L; A61L12/00; A61L12/08; A61L12/10; A61L12/102; A61L12/14; A61L12/143; C; C11; C11D; C11D17/00; C11D17/0039; C11D3/00; C11D3/0005; C11D3/0042; C11D3/0078; C11D3/16; C11D3/34; C11D3/3472; C11D3/38; C11D3/386; C11D3/38609; C11D3/39; C11D3/3942; C11D3/395; C11D3/3953; C11D3/3427
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
113 words
A method for disinfecting a lens which comprises: contacting a lens in a liquid medium with a chlorine dioxide precursor in the presence of an effective amount of an activator component selected from the group consisting of organic acid anhydride components, oxygen-releasing components and mixtures thereof to effect formation of a lens disinfecting amount of chlorine dioxide from said chlorine dioxide precursor in said liquid medium, thereby disinfecting said lens, said organic acid anhydride components being selected from the group consisting of anhydrides of carboxylic acids having 2 to about 30 carbon atoms and mixtures thereof, and said oxygen-releasing components being selected from the group consisting of perthiosulfates, persulfates, peroxysulfates and mixtures thereof.
Claim 2
Independent Claim
113 words
A method for disinfecting a lens which comprises: contacting a lens in a liquid medium with a chlorine dioxide precursor in the presence of an effective amount of an activator component selected from the group consisting of organic acid anhydride components, oxygen-releasing components and mixtures thereof to effect formation of a lens disinfecting amount of chlorine dioxide from said chlorine dioxide precursor in said liquid medium, thereby disinfecting said lens, said organic acid anhydride components being selected from the group consisting of anhydrides of carboxylic acids having 2 to about 30 carbon atoms and mixtures thereof, and said oxygen-releasing components being selected from the group consisting of perthiosulfates, persulfates, peroxysulfates and mixtures thereof.
Claim 3
Dependent Claim
37 words
The method of claim 1 wherein said liquid medium is an aqueous liquid medium and said contacting occurs at a pH in the range of about 6 to about 10, and said lens is a contact lens.
Claim 4
Dependent Claim
31 words
The method of claim 1 wherein said activator component comprises an organic acid anhydride selected from the group consisting of succinic anhydride, glutaric anhydride, glutaconic anhydride, maleic anhydride and mixtures thereof.
Claim 5
Dependent Claim
30 words
The method of claim 1 wherein both said chlorine dioxide precursor and said activator component are initially solid and are introduced into said liquid medium at substantially the same time.
Claim 6
Dependent Claim
34 words
The method of claim 1 which further comprises introducing a reducing component effective to chemically reduce at least a portion of the chlorine dioxide formed from said chlorine dioxide precursor in said liquid medium.
Claim 7
Dependent Claim
30 words
The method of claim 1 which further comprises contacting the lens in a liquid medium with at least one enzyme in an amount effective to remove debris from the lens.
Claim 8
Dependent Claim
24 words
The method of claim 6 wherein said enzyme and said activator component are each part of a single item introduced into said liquid medium.
Claim 9
Dependent Claim
28 words
The method of claim 7 wherein said item further comprises a delayed release component in an amount effective to release said enzyme prior to releasing said activator component.
Claim 10
Dependent Claim
130 words
A composition comprising a liquid medium including a chlorine dioxide precursor in an amount effective to form a lens disinfecting amount of chlorine dioxide; an activator component selected from the group consisting of organic acid anhydride components, oxygen-releasing components and mixtures thereof, said organic acid anhydride components being selected from the group consisting of anhydrides of carboxylic acids having 2 to about 30 carbon atoms and mixtures thereof, and said oxygen-releasing components being selected from the group consisting of perthiosulfates, persulfates, peroxysulfates and mixtures thereof, said activator component being present in an amount effective to effect the formation of a lens disinfecting amount of chlorine dioxide from said chlorine dioxide precursor; and a reducing component in an amount effective to chemically reduce all the chlorine dioxide in said liquid medium.
Claim 11
Dependent Claim
130 words
A composition comprising a liquid medium including a chlorine dioxide precursor in an amount effective to form a lens disinfecting amount of chlorine dioxide; an activator component selected from the group consisting of organic acid anhydride components, oxygen-releasing components and mixtures thereof, said organic acid anhydride components being selected from the group consisting of anhydrides of carboxylic acids having 2 to about 30 carbon atoms and mixtures thereof, and said oxygen-releasing components being selected from the group consisting of perthiosulfates, persulfates, peroxysulfates and mixtures thereof, said activator component being present in an amount effective to effect the formation of a lens disinfecting amount of chlorine dioxide from said chlorine dioxide precursor; and a reducing component in an amount effective to chemically reduce all the chlorine dioxide in said liquid medium.
Claim 12
Dependent Claim
31 words
The composition of claim 9 wherein said activator component comprises an organic acid anhydride selected from the group consisting of succinic anhydride, glutaric anhydride, glutaconic anhydride maleic anhydride, and mixtures thereof.
Claim 13
Dependent Claim
73 words
The composition of claim 9 wherein said activator component and said reducing component are present in a combination which further comprises at least one enzyme in an amount effective to substantially remove at least one type of debris from a debris laden contact lens and a delayed release component in an amount effective so that upon introduction into said liquid medium said enzyme is released before or after said activator component is released.
Claim 14
Dependent Claim
54 words
The composition of claim 9 wherein said activator component and said reducing component are present in a combination which further comprises a delayed release component in an amount effective so that upon introduction into said liquid medium said reducing component is released from said combination after said activator component is released from said combination.
Claim 15
Dependent Claim
144 words
A composition comprising at least one enzyme effective to remove debris from a contact lens; an activator component selected from the group consisting of organic acid anhydride components, oxygen-releasing components and mixtures thereof, said organic acid anhydride components being selected from the group consisting of anhydrides of carboxylic acids having 2 to about 30 carbon atoms and mixtures thereof, and said oxygen-releasing components being selected from the group consisting of perthiosulfates, persulfates, peroxysulfates and mixtures thereof, said activator component being present in an amount effective to effect the formation of a lens disinfecting amount of chlorine dioxide from a chlorine dioxide precursor in a liquid medium; and a delayed release component in an amount effective so that upon introduction of said composition into a liquid medium said enzyme is released into the liquid medium before said activator component is released into the liquid medium.
Claim 16
Dependent Claim
144 words
A composition comprising at least one enzyme effective to remove debris from a contact lens; an activator component selected from the group consisting of organic acid anhydride components, oxygen-releasing components and mixtures thereof, said organic acid anhydride components being selected from the group consisting of anhydrides of carboxylic acids having 2 to about 30 carbon atoms and mixtures thereof, and said oxygen-releasing components being selected from the group consisting of perthiosulfates, persulfates, peroxysulfates and mixtures thereof, said activator component being present in an amount effective to effect the formation of a lens disinfecting amount of chlorine dioxide from a chlorine dioxide precursor in a liquid medium; and a delayed release component in an amount effective so that upon introduction of said composition into a liquid medium said enzyme is released into the liquid medium before said activator component is released into the liquid medium.
Claim 17
Dependent Claim
28 words
The composition of claim 13 which further comprises a chlorine dioxide precursor capable of forming chlorine dioxide in a liquid medium in the presence of said activator component.
Claim 18
Dependent Claim
109 words
A composition comprising a solid chlorine dioxide precursor capable of forming chlorine dioxide in a liquid medium; and a solid activator component selected from the group consisting of organic acid anhydride components, oxygen-releasing components and mixtures thereof, said organic acid anhydride components being selected from the group consisting of anhydrides of carboxylic acids having 2 to about 30 carbon atoms and mixtures thereof, and said oxygen-releasing components being selected from the group consisting of perthiosulfates, peroxysulfates and mixtures thereof, said solid activator component being present in an amount effective to effect formation of a lens disinfecting amount of chlorine dioxide from a chlorine dioxide precursor in a liquid medium.
Claim 19
Dependent Claim
109 words
A composition comprising a solid chlorine dioxide precursor capable of forming chlorine dioxide in a liquid medium; and a solid activator component selected from the group consisting of organic acid anhydride components, oxygen-releasing components and mixtures thereof, said organic acid anhydride components being selected from the group consisting of anhydrides of carboxylic acids having 2 to about 30 carbon atoms and mixtures thereof, and said oxygen-releasing components being selected from the group consisting of perthiosulfates, peroxysulfates and mixtures thereof, said solid activator component being present in an amount effective to effect formation of a lens disinfecting amount of chlorine dioxide from a chlorine dioxide precursor in a liquid medium.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-06-27 | 1997-12-27 | 1998-06-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-06-27 | 2001-12-27 | 2002-06-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-06-27 | 2005-12-27 | 2006-06-28 | $7700.00 | Window Closed / Lapsed |