EP0426489A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Hydrogen peroxide destroying compositions and methods of using same
Assignee: Allergan Inc
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Filing: 1990-11-02
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Granted: —
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Expires: 2010-11-02
Abstract
Abstract A composition and method useful for destroying hydrogen peroxide in a liquid aqueous medium, such as that used to disinfect contact lenses, are disclosed. The composition comprises at least one hydrogen peroxide destroying component effective when released into a liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the liquid aqueous medium, and a barrier component acting to substantially prevent the release of the hydrogen peroxide destroying component for a period of time after the composition is initially contacted with a hydrogen peroxide-containing liquid aqueous medium. The barrier component includes a water soluble portion and a water insoluble portion. The hydrogen peroxide destroying component is situated so as to be released into the hydrogen peroxide-containing liquid aqueous medium in response to the dissolving of the water soluble portion into the hydrogen peroxide-containing liquid aqueous medium.
Inventors
- 👤 Peter Gyulai
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-24 02:43
CPC Classifications
A; A61; A61L; A61L12/00; A61L12/08; A61L12/12; A61L12/124; A61L12/126
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
117 words
A composition comprising at least one hydrogen peroxide destroying component effective when released into a liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the liquid aqueous medium, and a barrier component acting to substantially prevent the release of said hydrogen peroxide destroying component for a period of time after said composition is initially contacted with a hydrogen peroxide-containing liquid aqueous medium, said barrier component including a water soluble portion and a water insoluble portion, and said hydrogen peroxide destroying component being situated so as to be released into said hydrogen peroxide-containing liquid aqueous medium in response to the dissolving of said water soluble portion into said hydrogen peroxide-containing liquid aqueous medium.
Claim 2
Dependent Claim
117 words
A composition comprising at least one hydrogen peroxide destroying component effective when released into a liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the liquid aqueous medium, and a barrier component acting to substantially prevent the release of said hydrogen peroxide destroying component for a period of time after said composition is initially contacted with a hydrogen peroxide-containing liquid aqueous medium, said barrier component including a water soluble portion and a water insoluble portion, and said hydrogen peroxide destroying component being situated so as to be released into said hydrogen peroxide-containing liquid aqueous medium in response to the dissolving of said water soluble portion into said hydrogen peroxide-containing liquid aqueous medium.
Claim 3
Dependent Claim
43 words
The composition of claim 1 wherein said composition is structured so that said hydrogen peroxide destroying component is released into said hydrogen peroxide-containing liquid aqueous medium at a predetermined time after said composition is initially contacted with said hydrogen peroxide-containing liquid aqueous medium.
Claim 4
Dependent Claim
46 words
The composition of claim 1 wherein said composition (for example a tablet) is in the form of at least one item comprising a first layer and a second layer, said first layer including said hydrogen peroxide destroying component, and said second layer including said barrier component.
Claim 5
Dependent Claim
14 words
The composition of claim 3 wherein said second layer substantially surrounds said first layer.
Claim 6
Dependent Claim
32 words
The composition of any one of claims 1 to 4 wherein said hydrogen peroxide destroying component is a hydrogen peroxide reducing agent; or a peroxidase such as catalase; or a mixture thereof.
Claim 7
Dependent Claim
43 words
The composition of any one of the preceding claims wherein said hydrogen peroxide destroying component is selected from the group consisting of alkali metal thiosulfates, thiourea, alkali metal sulfites, thioglycerol, N-acetylcysteine, alkali metal formiates, ascorbic acid, isoascorbic acid, glyoxylic acid and mixtures thereof.
Claim 8
Dependent Claim
34 words
The composition of any one of the preceding claims wherein said water soluble portion is situated so as to create pores in said barrier component upon dissolving into said hydrogen peroxide-containing liquid aqueous medium.
Claim 9
Dependent Claim
21 words
The composition of any one of the preceding claims wherein said water soluble portion is distributed randomly in said barrier component.
Claim 10
Dependent Claim
31 words
The composition of any one of the preceding claims wherein said water soluble portion is sucrose; or sodium chloride; or potassium chloride or a mixture of any of the aforesaid substances.
Claim 11
Dependent Claim
36 words
The composition of claim 1 wherein said water insoluble portion is made of a polymeric material, for example a polymeric material derived from at least one vinyl functional monomer; suitably at least two vinyl functional monomers.
Claim 12
Dependent Claim
35 words
The composition of any one of the preceding claims wherein said water insoluble portion is made of a polymeric material selected from the group consisting of terpolymers of polyvinylchloride, polyvinylacetate and polyvinylalcohol and mixtures thereof.
Claim 13
Dependent Claim
36 words
The composition of claim 11 wherein said terpolymers include about 80% to about 95% by weight polyvinylchloride, about 0.5% to about 19% by weight of polyvinylacetate an about 0.5% to about 10% by weight of polyvinylalcohol.
Claim 14
Dependent Claim
41 words
The composition of any one of the preceding claims wherein said water soluble portion is present in an amount in the range of about 10% to about 97% by weight of the total of said soluble portion and said insoluble portion.
Claim 15
Dependent Claim
141 words
The composition of any one of the preceding claims which further comprises at least one enzyme (e.g. a peroxide active enzyme such as an enzyme of the Subtilisin A class) capable of removing protein-based debris from a contact lens in an amount effective to substantially remove the protein-based debris from a protein-based debris laden contact lens, said composition being structured so that upon introduction into said hydrogen peroxide-containing liquid aqueous medium said enzyme is released before or at substantially the same time as said hydrogen peroxide destroying component is released, said composition for example being in the form of at least one item comprising a core layer, a first coating layer and a second coating layer, said second coating layer including said enzyme, said first coating layer including said barrier component, and said core layer including said hydrogen peroxide destroying component.
Claim 16
Independent Claim
35 words
A method of decreasing the concentration of hydrogen peroxide in a liquid aqueous medium comprising: contacting a hydrogen peroxide-containing liquid aqueous medium with a composition as defined in any one of claims 1 to 14.
Claim 17
Independent Claim
50 words
A method of disinfecting a lens comprising: contacting a lens to be disinfected with a hydrogen peroxide-containing aqueous liquid medium at effective lens disinfecting conditions, thereby disinfecting said lens; and contacting said hydrogen peroxide-containing aqueous liquid medium with a composition as defined in any one of claims 1 to 14.
Claim 18
Dependent Claim
43 words
The method of claim 16 wherein the composition contains an enzyme as defined in claim 14 and wherein protein-based debris is removed from said contact lens to be disinfected at substantially the same time said contact lens to be disinfected is being disinfected.
References Cited (Backward Citations)
No citation records indexed.
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