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US5152912A Expired / Lapsed US ⏱️ 0.0 years remaining

Chlorine dioxide precursor containing compositions useful in disinfecting contact lenses

Assignee: Allergan Inc
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Filing: 1991-04-23
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Granted: 1992-10-06
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Expires: 2011-04-23
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Abstract

Abstract A method for disinfecting a lens is disclosed. The method comprises contacting a lens to be disinfected in a liquid medium with at least one chlorine dioxide precursor in the presence of at least one acidic component effective to increase the rate of formation of chlorine dioxide from the chlorine dioxide precursor, thereby disinfecting the lens; and adjusting the acidity of the liquid medium containing the disinfected lens. Compositions useful in the above-noted method are also disclosed.

Inventors

  • 👤 Anthony J. Dziabo
  • 👤 Hampar Karageozian
  • 👤 Paul S. Ripley

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 23:48
CPC Classifications
C; C11; C11D; C11D3/00; C11D3/0005; C11D3/0078; A; A61; A61L; A61L12/00; A61L12/08; A61L12/10; A61L12/102; A61L2/00; A61L2/16; A61L2/18; C11D3/16; C11D3/34; C11D3/3427

Claims Analysis

Total Claims: 33
Claim 1
Independent Claim 117 words
A contact lens disinfecting composition comprising a liquid medium containing at least one chlorine dioxide precursor in an amount effective to form a contact lens disinfecting amount of chlorine dioxide; and a combination comprising at least one solid acidic component in an amount effective to increase the acidity of said liquid medium when said acidity component is released into said liquid medium, and at least one solid acidity adjusting component in an amount effective to reduce the acidity of said liquid medium when said acidity adjusting component is released into said liquid medium, said combination being structured so that upon introduction into said liquid medium said acidity adjusting component is released after said acidic component is released.
Claim 2
Dependent Claim 117 words
A contact lens disinfecting composition comprising a liquid medium containing at least one chlorine dioxide precursor in an amount effective to form a contact lens disinfecting amount of chlorine dioxide; and a combination comprising at least one solid acidic component in an amount effective to increase the acidity of said liquid medium when said acidity component is released into said liquid medium, and at least one solid acidity adjusting component in an amount effective to reduce the acidity of said liquid medium when said acidity adjusting component is released into said liquid medium, said combination being structured so that upon introduction into said liquid medium said acidity adjusting component is released after said acidic component is released.
Claim 3
Dependent Claim 31 words
The composition of claim 1 wherein said combination is structured so that said acidity adjusting component is released at a predetermined time after said combination is introduced into said liquid medium.
Claim 4
Dependent Claim 32 words
The composition of claim 1 wherein said combination comprises a first layer and a second layer, said first layer including said acidic component and said second layer including said acidity adjusting component.
Claim 5
Dependent Claim 14 words
The composition of claim 3 wherein said first layer substantially surrounds said second layer.
Claim 6
Dependent Claim 25 words
The composition of claim 3 wherein said combination before introduction into said liquid medium is in the form of at least one tablet or pill.
Claim 7
Dependent Claim 24 words
The composition of claim 1 wherein said acidity adjusting component is selected from the group consisting of basic components, buffer components and mixtures thereof.
Claim 8
Dependent Claim 22 words
The composition of claim 1 wherein is selected from the group consisting of mineral acids, carboxylic acids, acidic salts and mixtures thereof.
Claim 9
Dependent Claim 30 words
The composition method of claim 1 wherein said acidic component is selected from the group consisting of alkali metal hydrogen phosphates, citric acid, lactic acid, tartaric acid and mixtures thereof.
Claim 10
Dependent Claim 59 words
The composition of claim 1 wherein said combination further comprises at least one enzyme capable of removing debris from a contact lens in an amount effective to remove debris from a debris laden contact lens, said combination being structured so that upon introduction into said liquid medium said enzyme is released before or after said acidic component is released.
Claim 11
Dependent Claim 41 words
The composition of claim 9 wherein said combination comprises a first layer, a second layer and a third layer, said first layer including said enzyme, said second layer including said acidic component, and said third layer including said acidity adjusting component.
Claim 12
Dependent Claim 38 words
The composition of claim 1 wherein said combination further comprises at least one reducing agent in an amount effective to chemically reduce chlorine dioxide in said liquid medium when said reducing agent is released into said liquid medium.
Claim 13
Dependent Claim 127 words
A contact lens disinfecting composition comprising a liquid medium containing at least one chlorine dioxide precursor in an amount effective to form a contact lens disinfecting amount of chlorine dioxide; and a combination comprising at least one enzyme capable of removing debris from a contact lens in an amount effective to remove debris from a protein-based debris laden contact lens present in said liquid medium when said at least one enzyme is released into said liquid medium, and at least one acidic component in an amount effective to increase the acidity of said liquid medium when said acidity component is released into said liquid medium, said combination being structured so that upon introduction into said liquid medium said enzyme is released before said acidic component is released.
Claim 14
Dependent Claim 127 words
A contact lens disinfecting composition comprising a liquid medium containing at least one chlorine dioxide precursor in an amount effective to form a contact lens disinfecting amount of chlorine dioxide; and a combination comprising at least one enzyme capable of removing debris from a contact lens in an amount effective to remove debris from a protein-based debris laden contact lens present in said liquid medium when said at least one enzyme is released into said liquid medium, and at least one acidic component in an amount effective to increase the acidity of said liquid medium when said acidity component is released into said liquid medium, said combination being structured so that upon introduction into said liquid medium said enzyme is released before said acidic component is released.
Claim 15
Dependent Claim 25 words
The composition of claim 12 wherein said acidic component is selected from the group consisting of mineral acids, carboxylic acids, acidic salts and mixtures thereof.
Claim 16
Dependent Claim 29 words
The composition of claim 12 wherein said acidic component is selected from the group consisting of alkali metal hydrogen phosphates, citric acid, lactic acid, tartaric acid and mixtures thereof.
Claim 17
Dependent Claim 21 words
The composition of claim 12 wherein said enzyme is selected from the group consisting of proteolytic enzymes, lipases and mixtures thereof.
Claim 18
Dependent Claim 21 words
The composition of claim 12 wherein said enzyme is selected from the group consisting of carbohydrate active enzymes and mixtures thereof.
Claim 19
Dependent Claim 21 words
The composition of claim 12 wherein said enzyme is selected from the group consisting of proteases, amylases, lipases and mixtures thereof.
Claim 20
Dependent Claim 121 words
A contact lens cleaning composition comprising a liquid medium containing at least one chlorine dioxide precursor in an amount effective to form a contact lens disinfecting amount of chlorine dioxide; and a combination comprising at least one enzyme in an amount effective to remove debris from a contact lens in said liquid medium when said enzyme is released into said liquid medium, and at least one acidity adjusting component in an amount effective to reduce the acidity of said liquid medium when said acidity adjusting component is released into said liquid medium, said combination being structured so that upon introduction into said liquid medium said enzyme is released substantially at the same time or after said acidity adjusting component is released.
Claim 21
Dependent Claim 121 words
A contact lens cleaning composition comprising a liquid medium containing at least one chlorine dioxide precursor in an amount effective to form a contact lens disinfecting amount of chlorine dioxide; and a combination comprising at least one enzyme in an amount effective to remove debris from a contact lens in said liquid medium when said enzyme is released into said liquid medium, and at least one acidity adjusting component in an amount effective to reduce the acidity of said liquid medium when said acidity adjusting component is released into said liquid medium, said combination being structured so that upon introduction into said liquid medium said enzyme is released substantially at the same time or after said acidity adjusting component is released.
Claim 22
Dependent Claim 38 words
The composition of claim 18 wherein said combination further comprises at least one reducing agent in an amount effective to chemically reduce chlorine dioxide in said liquid medium when said reducing agent is released into said liquid medium.
Claim 23
Dependent Claim 24 words
The composition of claim 18 wherein said acidity adjusting component is selected from the group consisting of basic components, buffer components and mixtures thereof.
Claim 24
Dependent Claim 21 words
The composition of claim 18 wherein said enzyme is selected from the group consisting of proteolytic enzymes, lipases and mixtures thereof.
Claim 25
Dependent Claim 21 words
The composition of claim 18 wherein said enzyme is selected from the group consisting of carbohydrate active enzymes and mixtures thereof.
Claim 26
Dependent Claim 21 words
The composition of claim 18 wherein said enzyme is selected from the group consisting of proteases, amylases, lipases and mixtures thereof.
Claim 27
Dependent Claim 178 words
A contact lens disinfecting precursor composition comprising a combination of at least one solid chlorine dioxide precursor in an amount effective to form a contact lens disinfecting amount of chlorine dioxide in a liquid medium into which said chlorine dioxide precursor is released; at least one solid acidic component in an amount effective when released into the liquid medium containing said chlorine dioxide precursor to effect the formation of a contact lens disinfecting amount of chlorine dioxide from said chlorine dioxide precursor in the liquid medium; and at least one solid acidity adjusting component in an amount effective when released into the liquid medium containing said chlorine dioxide precursor to reduce the acidity of the liquid medium containing said chlorine dioxide precursor, said combination being structured to allow said solid chlorine dioxide precursor and said solid acidic component to be introduced into the liquid medium at the same time and to allow said solid acidity adjusting component to be released into the liquid medium after said solid chlorine dioxide precursor and said solid acidic component are so released.
Claim 28
Dependent Claim 178 words
A contact lens disinfecting precursor composition comprising a combination of at least one solid chlorine dioxide precursor in an amount effective to form a contact lens disinfecting amount of chlorine dioxide in a liquid medium into which said chlorine dioxide precursor is released; at least one solid acidic component in an amount effective when released into the liquid medium containing said chlorine dioxide precursor to effect the formation of a contact lens disinfecting amount of chlorine dioxide from said chlorine dioxide precursor in the liquid medium; and at least one solid acidity adjusting component in an amount effective when released into the liquid medium containing said chlorine dioxide precursor to reduce the acidity of the liquid medium containing said chlorine dioxide precursor, said combination being structured to allow said solid chlorine dioxide precursor and said solid acidic component to be introduced into the liquid medium at the same time and to allow said solid acidity adjusting component to be released into the liquid medium after said solid chlorine dioxide precursor and said solid acidic component are so released.
Claim 29
Dependent Claim 23 words
The composition of claim 24 wherein said solid chlorine dioxide precursor is selected from the group consisting of metal chlorites and mixtures thereof.
Claim 30
Dependent Claim 14 words
The composition of claim 24 wherein said solid chlorine dioxide precursor is sodium chlorite.
Claim 31
Dependent Claim 30 words
The composition of claim 24 wherein said solid acidic component is selected from the group consisting of alkali metal hydrogen phosphates, citric acid, lactic acid, tartaric acid and mixtures thereof.
Claim 32
Dependent Claim 25 words
The composition of claim 10 wherein said combination before introduction into said liquid medium is in the form of at least one tablet or pill.
Claim 33
Dependent Claim 25 words
The composition of claim 18 wherein said combination before introduction into said liquid medium is in the form of at least one tablet or pill.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-10-06 1996-04-06 1996-10-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-10-06 2000-04-06 2000-10-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-10-06 2004-04-06 2004-10-06 $7700.00 Window Closed / Lapsed

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