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US4537764A
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Stabilized enzymatic dentifrice containing B-D-glucose and glucose oxidase
Assignee: LACLEDE PROFESSIONAL PRODUCTS Inc A CORP OF NEW YORK
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Filing: 1983-06-06
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Granted: 1985-08-27
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Expires: 2003-06-06
Abstract
Abstract An enzymatic dentifrice is provided which contains an enzyme system comprising Beta-D-glucose and glucose oxidase for producing hydrogen peroxide upon oral application of the dentifrice. The enzymatic dentifrice is stabilized against the production of hydrogen peroxide prior to oral application of the dentifrice by limiting any water in the dentifrice to an amount not more than about 10 wt. % based on the weight of the dentifrice.
Inventors
- 👤 Michael A. Pellico
- 👤 Robert E. Montgomery
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:51
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/64; A61K8/66
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
79 words
An enzymatic dentifrice comprising, per gram of dentifrice, from about 0.015 to about 0.6 millimoles of Beta-D-glucose and from about 0.5 to about 500 International Units of glucose oxidase for producing hydrogen peroxide upon oral application of said dentifrice, and limiting any water present in the dentifrice to an amount not more than about 10 wt. % based on the dentifrice weight to stabilize the dentifrice against the production of hydrogen peroxide prior to oral application of the dentifrice.
Claim 2
Dependent Claim
79 words
An enzymatic dentifrice comprising, per gram of dentifrice, from about 0.015 to about 0.6 millimoles of Beta-D-glucose and from about 0.5 to about 500 International Units of glucose oxidase for producing hydrogen peroxide upon oral application of said dentifrice, and limiting any water present in the dentifrice to an amount not more than about 10 wt. % based on the dentifrice weight to stabilize the dentifrice against the production of hydrogen peroxide prior to oral application of the dentifrice.
Claim 3
Dependent Claim
24 words
The dentifrice of claim 1 wherein the Beta-D-glucose is present in an amount from about 0.05 to about 0.5 millimoles per gram of dentifrice.
Claim 4
Dependent Claim
23 words
The dentifrice of claim 1 wherein Beta-D-glucose is present in an amount from about 0.1 to about 0.2 millimoles per gram of dentifrice.
Claim 5
Dependent Claim
25 words
The dentifrice of claim 1 wherein glucose oxidase is present in an amount from about 1.0 to about 100 International Units per gram of dentifrice.
Claim 6
Dependent Claim
25 words
The dentifrice of claim 1 wherein glucose oxidase is present in an amount from about 5.0 to about 50 International Units per gram of dentifrice.
Claim 7
Independent Claim
94 words
A method for cleaning an oral dental surface which comprises treating the dental surface with an enzymatic dentifrice containing, per gram of dentifrice, from about 0.015 to about 0.6 millimoles of Beta-D-glucose and from about 0.5 to about 500 International Units of glucose oxidase for producing hydrogen peroxide upon oral application of said dentifrice, and limiting any water present in the dentifrice to an amount not more than about 10 wt. % based on the dentifrice weight to stablize the dentifrice against the production of hydrogen peroxide prior to oral application of the dentifrice.
Claim 8
Independent Claim
94 words
A method for cleaning an oral dental surface which comprises treating the dental surface with an enzymatic dentifrice containing, per gram of dentifrice, from about 0.015 to about 0.6 millimoles of Beta-D-glucose and from about 0.5 to about 500 International Units of glucose oxidase for producing hydrogen peroxide upon oral application of said dentifrice, and limiting any water present in the dentifrice to an amount not more than about 10 wt. % based on the dentifrice weight to stablize the dentifrice against the production of hydrogen peroxide prior to oral application of the dentifrice.
Claim 9
Dependent Claim
24 words
The method of claim 6 wherein the Beta-D-glucose is present in an amount from about 0.05 to about 0.5 millimoles per gram of dentifrice.
Claim 10
Dependent Claim
24 words
The method of claim 6 wherein the Beta-D-glucose is present in an amount from about 0.1 to about 0.2 millimoles per gram of dentifrice.
Claim 11
Dependent Claim
25 words
The method of claim 6 wherein glucose oxidase is present in an amount from about 1.0 to about 100 International Units per gram of dentifrice.
Claim 12
Dependent Claim
25 words
The method of claim 6 wherein glucose oxidase is present in an amount from about 5.0 to about 50 International Units per gram of dentifrice.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-08-26 | 1989-02-25 | 1989-08-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-08-26 | 1993-02-25 | 1993-08-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-08-26 | 1997-02-25 | 1997-08-27 | $7700.00 | Window Closed / Lapsed |