US4082841A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dentifrice
Assignee: CPPD Inc A CORP OF
•
Filing: 1976-10-29
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Granted: 1978-04-04
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Expires: 1996-10-29
Abstract
Abstract There is disclosed in this specification an improved composition for reducing dental plaque and calculus formation, comprising zinc ions and an organoleptically acceptable enzyme, which may be a protease, carbohydrase, or lipase, or mixtures of these enzymes.
Inventors
- 👤 Morton Pader
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:01
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/25; A61K8/27; A61K8/30; A61K8/64; A61K8/66; A61Q; A61Q11/00
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
80 words
A fluoride-free toothpaste composition capable of reducing dental plaque and calculus consisting essentially of by weight: ______________________________________
Dental Polishing Agent
1% - 70%
Humectant and water 30% - 80%
Foaming Agent 0% - 5%
Non-enzyme bound, pharmaceuti-
cally acceptable zinc salt of
acetate, benzoate, borate, car-
bonate, citrate, dl-lactate
trihydrate, phenolsulfonate,
silicate, an alkanoate having
8 to 18 carbon atoms, salicylate,
stannate, sulfate, tannate or
titanate; 0.1% - 20%
Protease, carbohydrase or lip-
ase enzyme preparation
0.1% - 20%
______________________________________
Claim 2
Dependent Claim
80 words
A fluoride-free toothpaste composition capable of reducing dental plaque and calculus consisting essentially of by weight: ______________________________________
Dental Polishing Agent
1% - 70%
Humectant and water 30% - 80%
Foaming Agent 0% - 5%
Non-enzyme bound, pharmaceuti-
cally acceptable zinc salt of
acetate, benzoate, borate, car-
bonate, citrate, dl-lactate
trihydrate, phenolsulfonate,
silicate, an alkanoate having
8 to 18 carbon atoms, salicylate,
stannate, sulfate, tannate or
titanate; 0.1% - 20%
Protease, carbohydrase or lip-
ase enzyme preparation
0.1% - 20%
______________________________________
Claim 3
Dependent Claim
21 words
The toothpaste composition defined in claim 1 wherein the dental polishing agent is a mixture of silica xerogel and silica aerogel.
Claim 4
Dependent Claim
14 words
The toothpaste composition defined in claim 1 wherein the zinc salt is zinc phenolsulfonate.
Claim 5
Dependent Claim
14 words
The toothpaste composition defined in claim 1 wherein the zinc salt is zinc citrate.
Claim 6
Dependent Claim
18 words
The toothpaste composition defined in claim 1 wherein the enzyme preparation is a protease derived from Bacillus subtilis.
Claim 7
Dependent Claim
18 words
The toothpaste composition defined in claim 1 wherein the enzyme preparation is a lipase derived from animal pancreas.
Claim 8
Dependent Claim
14 words
The toothpaste composition defined in claim 1 wherein the enzyme preparation is an amylase.
Claim 9
Dependent Claim
41 words
The toothpaste composition defined in claim 1 wherein (a) the dental polishing agent is a mixture of silica xerogel and silica aerogel; (b) the zinc salt is zinc phenol-sulfonate; and (c) the enzyme preparation is a protease derived from Bacillus subtilis.
Claim 10
Dependent Claim
66 words
A fluoride free toothpaste composition capable of reducing dental plaque and calculus consisting essentially of by weight: ______________________________________
% Silica xerogel 14.00%
% Silica aerogel 8.00
% Binder 0.30
% Humectants and water 72.06
% Protease enzyme preparation derived
from Bacillus subtilis 0.25
% Zinc phenolsulfonate 1.00
% Sodium lauryl sulfate 1.47
% Chloroform 0.80
% Colorant, flavoring substance
sweetener, halogenated 2.12
germicide, preservative 100.00%
______________________________________
Claim 11
Dependent Claim
66 words
A fluoride free toothpaste composition capable of reducing dental plaque and calculus consisting essentially of by weight: ______________________________________
% Silica xerogel 14.00%
% Silica aerogel 8.00
% Binder 0.30
% Humectants and water 72.06
% Protease enzyme preparation derived
from Bacillus subtilis 0.25
% Zinc phenolsulfonate 1.00
% Sodium lauryl sulfate 1.47
% Chloroform 0.80
% Colorant, flavoring substance
sweetener, halogenated 2.12
germicide, preservative 100.00%
______________________________________
Claim 12
Dependent Claim
28 words
A process for inhibiting the rate of accumulation of dental plaque and calculus on a dental substrate comprising contacting said dental substrate with the composition of claim 1.
Claim 13
Dependent Claim
15 words
A process according to claim 10 wherein said substrate is a human tooth in vivo.
Claim 14
Dependent Claim
12 words
A process according to claim 10 wherein said substrate is a denture.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-04-03 | 1981-10-03 | 1982-04-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-04-03 | 1985-10-03 | 1986-04-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-04-03 | 1989-10-03 | 1990-04-04 | $7700.00 | Window Closed / Lapsed |