Anticalculus composition

Claim 2

An oral composition capable of retarding the development of dental calculus consisting essentially of from about 0.05% to about 4% zinc ions and about 0.03% to about 0.5% of a non-toxic, organoleptically acceptable antibacterial agent capable of inhibiting the growth of gram-positive oral microflora for at least about three hours in an orally acceptable medium, said antibacterial agent being selected from the group consisting of 3,4',5-tribromosalicylanilide, the zinc derivative of 3,4',5-tribromosalicylanilide, 3,4',5-trichlorosalicylanilide, the zinc derivative of 3,4',5-trichlorosalicylanilide, 3,5-dibromo-4'-trifluromethylsalicylanilide, the zinc derivative of 3,5-dibromo-4'-trifluoromethylsalicylanilide, 2,4,4'-trichloro-2'-hydroxydiphenyl ether, tyrothricin, chlorhexidine digluconate, chlorhexidine diacetate, quaternary ammonium compounds wherein said quaternary ammonium compounds are diisobutylphenoxyethoxyethyldimethylbenzylammonium chloride, diisobutylcresoxyethoxyethyldimethylbenzylammonium chloride, N-methyl-N-(2-hydroxyethyl)-N-(2-hydroxydodecyl)N-benzyl ammonium chloride, cetyl trimethylammonium bromide, stearyl trimethylammonium bromide, oleyl dimethylethylammonium bromide, lauryldimethylchlorethoxyethylammonium chloride, lauryldimethylbenzylammonium chloride, alkyl(C 8 -C 18 ) dimethyl (3,4-dichlorobenzyl)-ammonium chloride, lauryl isoquinolinium bromide, N(lauroyloxyethylaminoformylmethyl)pyridinium chloride, and mixtures thereof.

Claim 3

An oral composition in accordance with claim 1, wherein said orally acceptable medium comprises ethyl alcohol and water in a ratio of about 1:20 to about 1:2, respectively.

Claim 4

An oral composition in accordance with claim 1, wherein said zinc ions are derived from a zinc salt selected from the group consisting of zinc sulfate, zinc chloride, zinc acetate, zinc phenolsulfonate, zinc borate, zinc bromide, zinc nitrate, zinc glycerophosphate, zinc benzoate, zinc carbonate, zinc citrate, zinc hexafluorosilicate, zinc dl-lactate trihydrate, zinc oxide, zinc peroxide, zinc salicylate, zinc silicate, zinc soaps of fatty acids having 8-18 carbon atoms, zinc stannate, zinc tannate, zinc tartrate, zinc titanate, zinc tetrafluoroborate, and mixtures thereof.

Claim 5

An oral composition in accordance with claim 1, wherein said antibacterial agent is a bacteriostat.

Claim 6

An oral composition in accordance with claim 1, wherein said antibacterial agent is 3,4', 5-tribromosalicylanilide.

Claim 7

An oral composition in accordance with claim 1, wherein said antibacterial agent is the zinc derivative of 3,4',5-tribromosalicylanilide.

Claim 8

An oral composition in accordance with claim 1, wherein said antibacterial agent is 2',4,4'-trichloro-2-hydroxydiphenyl ether.

Claim 9

An oral composition in accordance with claim 1, wherein said zinc ions are derived from zinc phenolsulfonate and said antibacterial agent is the zinc derivative of 3,4',5-tribromosalicylanilide.

Claim 10

An oral composition in accordance with claim 1, wherein said antibacterial agent is selected from chlorohexidine digluconate and chlorhexidine diacetate.

Claim 11

An oral composition capable of retarding the development of plaque and dental calculus consisting essentially of zinc ions, and antibacterial agent and a particulate inorganic dental polishing agent, said zinc ions being present in the proportion of about 0.05% to about 4% and being furnished by a soluble zinc compound, said antibacterial agent being present within the range of about 0.03% to about 0.5%, and capable of inhibiting the growth of gram-positive oral microflora at least about three hours being selected from the group consisting of 3,4',5-tribromosalicylanilide, the zinc derivative of 3,4',5-tribromosalicylanilide, 3,4',5-trichlorosalicylanilide, the zinc derivative of 3,4',5-trichlorosalicylanilide, 3,5-dibromo-4'-trifluoromethylsalicylanilide, the zinc derivative of 3,5-dibromo-4'-trifluoromethylsalicylanilide, 2,4,4'-trichloro-2'-hydroxydiphenyl ether, tyrothricin, chlorhexidine digluconate, chlorhexidine diacetate, quaternary ammonium compounds wherein said quaternary ammonium compounds are diisobutylphenoxyethoxyethyldimethylbenzylammonium chloride, diisobutylcresoxyethoxyethyldimethylbenzylammonium chloride, N-methyl-N-(2-hydroxyethyl)-N-(2-hydroxydodecyl)N-benzylammonium chloride, cetyl trimethylammonium bromide, stearyl trimethylammonium bromide, oleyl dimethylethylammonium bromide, lauryldimethylchlorethoxyethylammonium chloride, lauryldimethylbenzylammonium chloride, alkyl(C 8 -C 18 ) dimethyl (3,4-dichlorobenzyl)-ammonium chloride, lauryl isoquinolinium bromide, N(lauroyloxyethylaminoformylmethyl)pyridinium chloride and mixtures thereof.

Claim 12

An oral composition capable of retarding the development of plaque and dental calculus consisting essentially of zinc ions, and antibacterial agent and a particulate inorganic dental polishing agent, said zinc ions being present in the proportion of about 0.05% to about 4% and being furnished by a soluble zinc compound, said antibacterial agent being present within the range of about 0.03% to about 0.5%, and capable of inhibiting the growth of gram-positive oral microflora at least about three hours being selected from the group consisting of 3,4',5-tribromosalicylanilide, the zinc derivative of 3,4',5-tribromosalicylanilide, 3,4',5-trichlorosalicylanilide, the zinc derivative of 3,4',5-trichlorosalicylanilide, 3,5-dibromo-4'-trifluoromethylsalicylanilide, the zinc derivative of 3,5-dibromo-4'-trifluoromethylsalicylanilide, 2,4,4'-trichloro-2'-hydroxydiphenyl ether, tyrothricin, chlorhexidine digluconate, chlorhexidine diacetate, quaternary ammonium compounds wherein said quaternary ammonium compounds are diisobutylphenoxyethoxyethyldimethylbenzylammonium chloride, diisobutylcresoxyethoxyethyldimethylbenzylammonium chloride, N-methyl-N-(2-hydroxyethyl)-N-(2-hydroxydodecyl)N-benzylammonium chloride, cetyl trimethylammonium bromide, stearyl trimethylammonium bromide, oleyl dimethylethylammonium bromide, lauryldimethylchlorethoxyethylammonium chloride, lauryldimethylbenzylammonium chloride, alkyl(C 8 -C 18 ) dimethyl (3,4-dichlorobenzyl)-ammonium chloride, lauryl isoquinolinium bromide, N(lauroyloxyethylaminoformylmethyl)pyridinium chloride and mixtures thereof.

Claim 13

An oral composition in accordance with claim 10, wherein said zinc ions are present in the proportion of about 0.2% to about 1.5%.

Claim 14

An oral composition in accordance with claim 10, wherein said zinc ions are present within the range of about 0.05% to about 0.5%.

Claim 15

An oral composition in accordance with claim 10, wherein said zinc ions are derived from phenolsulfonate and said antibacterial agent is the zinc derivative of 3,4',5-tribromosalicylanilide.

Claim 16

An oral composition in accordance with claim 10, wherein said zinc ions are derived from zinc citrate and said antibacterial agent is the zinc derivative of 3,4',5-tribromosalicylanilide.

Claim 17

An oral composition in accordance with claim 10, wherein said zinc ions are derived from zinc citrate and wherein said zinc citrate is attached to particles of said particulate dental polishing agent.

Claim 20

A method in accordance with claim 16 wherein said zinc ions are derived from zinc phenolsulfonate and said antibacterial agent is the zinc derivative of 3,4',5-tribromosalicylanilide.

Claim 21

An oral composition in accordance with claim 1 wherein said antibacterial agent is a (C 8-18 ) alkyl pyridinium bromide or a (C 8-18 ) alkyl pyridinium chloride.

Claim 22

An oral composition in accordance with claim 10 wherein said antibacterial agent is a (C 8-18 ) alkyl pyridinium bromide or a (C 8-18 ) alkyl pyridinium chloride.

Claim 23

A method in accordance with claim 16 wherein said antibacterial agent is a (C 8-18 ) alkyl pyridinium bromide, or a (C 8-18 ) alkyl pyridinium chloride.