Patent US2668403A successfully refreshed from Google Patents.
Patent US4082841A successfully refreshed from Google Patents.
US4082841A
Expired / Lapsed
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Dentifrice
Assignee: CPPD Inc A CORP OF
•
Filing: 1976-10-29
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Granted: 1978-04-04
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Expires: 1996-10-29
Abstract
Abstract There is disclosed in this specification an improved composition for reducing dental plaque and calculus formation, comprising zinc ions and an organoleptically acceptable enzyme, which may be a protease, carbohydrase, or lipase, or mixtures of these enzymes.
Inventors
- 👤 Morton Pader
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:48
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/25; A61K8/27; A61K8/30; A61K8/64; A61K8/66; A61Q; A61Q11/00
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
80 words
A fluoride-free toothpaste composition capable of reducing dental plaque and calculus consisting essentially of by weight: ______________________________________
Dental Polishing Agent
1% - 70%
Humectant and water 30% - 80%
Foaming Agent 0% - 5%
Non-enzyme bound, pharmaceuti-
cally acceptable zinc salt of
acetate, benzoate, borate, car-
bonate, citrate, dl-lactate
trihydrate, phenolsulfonate,
silicate, an alkanoate having
8 to 18 carbon atoms, salicylate,
stannate, sulfate, tannate or
titanate; 0.1% - 20%
Protease, carbohydrase or lip-
ase enzyme preparation
0.1% - 20%
______________________________________
Claim 2
Dependent Claim
80 words
A fluoride-free toothpaste composition capable of reducing dental plaque and calculus consisting essentially of by weight: ______________________________________
Dental Polishing Agent
1% - 70%
Humectant and water 30% - 80%
Foaming Agent 0% - 5%
Non-enzyme bound, pharmaceuti-
cally acceptable zinc salt of
acetate, benzoate, borate, car-
bonate, citrate, dl-lactate
trihydrate, phenolsulfonate,
silicate, an alkanoate having
8 to 18 carbon atoms, salicylate,
stannate, sulfate, tannate or
titanate; 0.1% - 20%
Protease, carbohydrase or lip-
ase enzyme preparation
0.1% - 20%
______________________________________
Claim 3
Dependent Claim
21 words
The toothpaste composition defined in claim 1 wherein the dental polishing agent is a mixture of silica xerogel and silica aerogel.
Claim 4
Dependent Claim
14 words
The toothpaste composition defined in claim 1 wherein the zinc salt is zinc phenolsulfonate.
Claim 5
Dependent Claim
14 words
The toothpaste composition defined in claim 1 wherein the zinc salt is zinc citrate.
Claim 6
Dependent Claim
18 words
The toothpaste composition defined in claim 1 wherein the enzyme preparation is a protease derived from Bacillus subtilis.
Claim 7
Dependent Claim
18 words
The toothpaste composition defined in claim 1 wherein the enzyme preparation is a lipase derived from animal pancreas.
Claim 8
Dependent Claim
14 words
The toothpaste composition defined in claim 1 wherein the enzyme preparation is an amylase.
Claim 9
Dependent Claim
41 words
The toothpaste composition defined in claim 1 wherein (a) the dental polishing agent is a mixture of silica xerogel and silica aerogel; (b) the zinc salt is zinc phenol-sulfonate; and (c) the enzyme preparation is a protease derived from Bacillus subtilis.
Claim 10
Dependent Claim
66 words
A fluoride free toothpaste composition capable of reducing dental plaque and calculus consisting essentially of by weight: ______________________________________
% Silica xerogel 14.00%
% Silica aerogel 8.00
% Binder 0.30
% Humectants and water 72.06
% Protease enzyme preparation derived
from Bacillus subtilis 0.25
% Zinc phenolsulfonate 1.00
% Sodium lauryl sulfate 1.47
% Chloroform 0.80
% Colorant, flavoring substance
sweetener, halogenated 2.12
germicide, preservative 100.00%
______________________________________
Claim 11
Dependent Claim
66 words
A fluoride free toothpaste composition capable of reducing dental plaque and calculus consisting essentially of by weight: ______________________________________
% Silica xerogel 14.00%
% Silica aerogel 8.00
% Binder 0.30
% Humectants and water 72.06
% Protease enzyme preparation derived
from Bacillus subtilis 0.25
% Zinc phenolsulfonate 1.00
% Sodium lauryl sulfate 1.47
% Chloroform 0.80
% Colorant, flavoring substance
sweetener, halogenated 2.12
germicide, preservative 100.00%
______________________________________
Claim 12
Dependent Claim
28 words
A process for inhibiting the rate of accumulation of dental plaque and calculus on a dental substrate comprising contacting said dental substrate with the composition of claim 1.
Claim 13
Dependent Claim
15 words
A process according to claim 10 wherein said substrate is a human tooth in vivo.
Claim 14
Dependent Claim
12 words
A process according to claim 10 wherein said substrate is a denture.
References Cited (Backward Citations)
US2527686A
Cited
US3194738A
Cited
US3235460A
Cited
GB1033229A
Cited
FR4675M
Cited
US3498882A
Cited
US3538230A
Cited
US3630924A
Cited
US3590121A
Cited
US3751561A
Cited
GB1296952A
Cited
ZA71701B
Cited
US3733399A
Cited
US4022880A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-04-03 | 1981-10-03 | 1982-04-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-04-03 | 1985-10-03 | 1986-04-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-04-03 | 1989-10-03 | 1990-04-04 | $7700.00 | Window Closed / Lapsed |