US3855142A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Enzymatic denture cleanser
Assignee: Lever Brothers Co
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Filing: 1973-09-14
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Granted: 1974-12-17
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Expires: 1993-09-14
Abstract
Abstract A denture cleanser comprises a lipolytic enzyme of mammalian, microbial, or plant origin admixed with a buffered compatible carrier medium. To decrease the rate of formation of plaque or calculus, or to reduce the amount of accumulated deposits on dentures, the dentures are soaked for a period of 1 to 24 hours in an aqueous medium containing the above-mentioned cleanser.
Inventors
- 👤 M Pader
- 👤 C Richberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 00:45
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/64; A61K8/66; A61Q; A61Q11/00; A61Q11/02; C; C11; C11D; C11D3/00; C11D3/02; C11D3/04; C11D3/06; C11D3/16; C11D3/38; C11D3/386; C11D3/38627
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
64 words
A DENTURE CLEANSER COMPOSITION COMPRISING A LIPOLHTIC ENZYME AT A CONCENTRATION TO PROVIDE LIPOLYTIC ACTIVITY OF ABOUT 20 TO ABOUT 50,000 LIPASE UNITS IN 100 ML OF A SOLUTION OF SAID COMPOSITIONS, ADMIXED WITH A BUFFERING AGENT, SAID BUFFERING AGENT BEING CAPABLE OFF PROVIDING A PH OF ABOUT 4.5 TO ABOUT 10 AND BEING INERT WITH RESPECT TO THE LIPOLYTIC ACTION OF THE ENZYME.
Claim 2
Dependent Claim
64 words
A DENTURE CLEANSER COMPOSITION COMPRISING A LIPOLHTIC ENZYME AT A CONCENTRATION TO PROVIDE LIPOLYTIC ACTIVITY OF ABOUT 20 TO ABOUT 50,000 LIPASE UNITS IN 100 ML OF A SOLUTION OF SAID COMPOSITIONS, ADMIXED WITH A BUFFERING AGENT, SAID BUFFERING AGENT BEING CAPABLE OFF PROVIDING A PH OF ABOUT 4.5 TO ABOUT 10 AND BEING INERT WITH RESPECT TO THE LIPOLYTIC ACTION OF THE ENZYME.
Claim 3
Dependent Claim
15 words
A denture cleanser in accordance with claim 1 wherein said enzyme is of mammalian origin.
Claim 4
Dependent Claim
15 words
A denture cleanser in accordance with claim 1 wherein said enzyme is of microbial origin.
Claim 5
Dependent Claim
15 words
A denture cleanser in accordance with claim 1 wherein said enzyme is of plant origin.
Claim 6
Dependent Claim
27 words
A denture cleanser in accordance with claim 1 wherein said enzyme is a castor bean lipase and said buffering agent provides a pH of 4.7 and 5.0.
Claim 7
Dependent Claim
39 words
A denture cleanser in accordance with claim 1 wherein said enzyme has lipolytic activity as its major function and wherein said buffering agent comprises a mixture of sodium or potassium orthophosphates capable of providing a pH of about 7.4.
Claim 8
Dependent Claim
15 words
A denture cleanser in accordance with claim 1 wherein said cleanser is in tablet form.
Claim 9
Dependent Claim
34 words
A composition in accordance with claim 1 capable of retarding the accumulation of plaque or calculus on dentures comprising a pancreatic lipase and a buffering agent capable of providing a pH of about 7.4.
Claim 10
Dependent Claim
47 words
A denture cleanser composition in accordance with claim 1 comprising a lipolytic enzyme, a compatible buffering agent and as an extender for said buffering agent, an enzyme-compatible, non-aqueous, water-soluble dispensing medium selected from the group consisting of water-soluble monohydric alcohols, water-soluble polyhydric alcohols and water-soluble ethers thereof.
Claim 11
Dependent Claim
43 words
A denture cleanser in accordance with claim 9 wherein said enzyme has lipolytic activity as its major function and has an activity of about 355 lipase units per 10 milligrams, said buffering agent is sodium bicarbonate, and said non-aqueous, water-soluble medium is glycerol.
Claim 12
Dependent Claim
47 words
An aqueous medium capable of retarding the accumulation of plaque of calculus on dentures comprising water and a lipolytic enzyme at a concentration to provide between about 20 units and 50,000 units per 100 millimeters, said aqueous medium having a buffered pH between about 4.5 and 10.
Claim 13
Dependent Claim
47 words
An aqueous medium capable of retarding the accumulation of plaque of calculus on dentures comprising water and a lipolytic enzyme at a concentration to provide between about 20 units and 50,000 units per 100 millimeters, said aqueous medium having a buffered pH between about 4.5 and 10.
Claim 14
Dependent Claim
85 words
A denture cleanser composition in accordance with claim 1 comprising a lipolytic enzyme, a compatible buffering agent and as an extender for said buffering agent an enzyme-compatible, non-aqueous, water-soluble dispensing medium selected from the group consisting of ethanol, n-propanol, isopropanol, ethylene glycol, propylene glycol, hexylene glycol, heptamethylene glycol, glycerol, diethylene glycol, triethylene glycol, the mono-alkyl ethers of ethylene glycol and diethylene glycol wherein the alkyl group has from 1 to about 4 carbon atoms, polyethylene glycols having molecular weights up to about 1,500, and dioxane.
Claim 15
Dependent Claim
96 words
A process for decreasing the rate of accumulation of plaque and calculus on dentures comprising maintaining said dentures in contact with an aqueous medium comprising water, a lipolytic enzyme at a concentration to provide lipolytic activity of about 20 to about 50,000 lipase units peR 100 milliliters of solution, and a buffering agent, said buffering agent being capable of providing a pH of about 4.5 to about 10, and being inert with respect to the lipolytic action of the enzyme, and said contact being maintained for a period of about 1 minute to about 24 hours.
Claim 16
Dependent Claim
96 words
A process for decreasing the rate of accumulation of plaque and calculus on dentures comprising maintaining said dentures in contact with an aqueous medium comprising water, a lipolytic enzyme at a concentration to provide lipolytic activity of about 20 to about 50,000 lipase units peR 100 milliliters of solution, and a buffering agent, said buffering agent being capable of providing a pH of about 4.5 to about 10, and being inert with respect to the lipolytic action of the enzyme, and said contact being maintained for a period of about 1 minute to about 24 hours.
Claim 17
Dependent Claim
28 words
A process in accordance with claim 13 wherein said lipolytic enzyme is of microbial origin and has a lipase activity of about 282 lipase units per 10 milligrams.
Claim 18
Dependent Claim
15 words
A process in accordance with claim 13 wherein said lipolytic enzyme is of mammalian origin.
Claim 19
Dependent Claim
15 words
A process in accordance with claim 13 wherein said lipolytic enzyme is of plant origin.
References Cited (Backward Citations)
US2922749A
Cited
US3451935A
Cited
US3519379A
Cited
US3557002A
Cited
US3630924A
Cited
US3635828A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-12-16 | 1978-06-17 | 1978-12-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-12-16 | 1982-06-17 | 1982-12-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-12-16 | 1986-06-17 | 1986-12-17 | $7700.00 | Window Closed / Lapsed |