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US6743248B2 Expired / Lapsed US ⏱️ 0.0 years remaining

Pretreatment method for enhancing tissue adhesion

Assignee: NeoMend Inc
•
Filing: 2000-04-13
•
Granted: 2004-06-01
•
Expires: 2020-04-13
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Abstract

Abstract A closure device is provided for sealing a puncture in a body vessel. The closure device includes an energy delivery device for delivering energy to tissue adjacent the vessel puncture which enhances an adhesiveness of the tissue to a closure composition precursor. The closure device includes a sealer/dilator for dilating tissue adjacent a vessel puncture, at least one closure composition precursor lumen within The sealer/dilator having an entrance part adjacent the proximal end of the sealer/dilator through which one or more fluent closure composition precursors can be delivered into the closure composition precursor lumen and an exit port adjacent the distal end of the sealer/dilator through which the one or more fluent closure composition precursors can be delivered outside the vessel adjacent the vessel puncture, and a plugging catheter for positioning within the vessel puncture, the plugging catheter extending distally from the sealer/dilator and including at least one position sensing mechanism such that the exit port of the closure composition precursor lumen is outside the vessel when the at least one position sensing mechanism is detected outside the vessel.

Inventors

  • 👤 Stuart D. Edwards
  • 👤 Thomas Wehman
  • 👤 Theodore L. Parker
  • 👤 Eugene V. Skalnyi
  • 👤 Theodore Kucklick
  • 👤 John Evans

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 23:57
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/00491; A61B17/0057; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/148; A61B18/1485; A61M; A61M16/00; A61M16/04; A61M16/0475; A61M16/0477; A61M16/0481; A61M25/00; A61M25/01; A61M25/06; A61M25/0662; A61B17/34; A61B17/3415; A61B18/1482; A61B18/1487; A61B18/1492; A61B18/18; A61B18/1815; A61B2017/00017; A61B2017/00022; A61B2017/00084; A61B2017/00106; A61B17/00234; A61B2017/00292; A61B2017/003; A61B2017/00495; A61B2017/005; A61B2017/00637; A61B2017/00646; A61B2017/0065; A61B2017/00672; A61B17/22; A61B2017/22051; A61B2017/22065; A61B2017/22067; A61B2017/348; A61B2017/3492; A61B17/42; A61B2017/4216; A61B2018/00005; A61B2018/00011; A61B2018/00023; A61B2018/00029; A61B2018/00053; A61B2018/00059; A61B2018/00065; A61B2018/00071; A61B2018/00077; A61B2018/00083; A61B2018/00107; A61B2018/00113; A61B2018/00148; A61B2018/00214; A61B2018/0022; A61B2018/00315; A61B2018/00482; A61B2018/00494; A61B2018/00559; A61B2018/00571; A61B2018/00577; A61B2018/00636; A61B2018/00642; A61B2018/00654; A61B2018/00666; A61B2018/00678; A61B2018/00696; A61B2018/00702; A61B2018/00708; A61B2018/00726; A61B2018/00755; A61B2018/00761; A61B2018/00773; A61B2018/00791; A61B2018/00797; A61B2018/00815; A61B2018/00821; A61B2018/00827; A61B2018/00869; A61B2018/00875; A61B2018/00886; A61B2018/00892; A61B2018/00898; A61B2018/0091; A61B2018/00916; A61B2018/00982; A61B2018/044; A61B2018/046; A61B18/1206; A61B2018/124; A61B2018/1246; A61B2018/1253; A61B2018/126; A61B2018/1273; A61B2018/1467; A61B2018/1472; A61B90/00; A61B90/06; A61B2090/064; A61B90/36; A61B90/361; A61B2090/3614; A61B90/37; A61B2090/378; A61B2090/3782; A61B2218/00; A61B2218/001; A61B2218/002; A61M16/0003; A61M2016/0027; A61M25/10; A61M2025/1043; A61M2025/1052; A61M2025/1086; A61M25/1002; A61M3/00; A61M3/02; A61M3/0279

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 224 words
An assembly for introducing a closure material to seal a puncture site in a vessel, the closure material comprising a mixture of a first and a second fluid composition, the assembly comprising a catheter having a proximal end and a distal end; at least one fluid delivery port adjacent the catheter distal end to occupy a position outside the vessel adjacent the puncture site; an expandable member distal to the fluid delivery port to extend through the puncture site and occupy a position inside the vessel while the at least one fluid delivery port occupies a position adjacent the vessel puncture site outside the vessel; a fluid delivery lumen in the catheter in fluid communication with the fluid delivery port; a guidewire lumen in the catheter sized to accommodate passage of a guide wire; one or more dispensers adjacent the catheter proximal end in fluid communication with the catheter lumen for dispensing the first and second fluid compositions into the catheter lumen; an actuator for causing the first and second fluid compositions to be dispensed from the one or more dispensers for passage through the catheter lumen; and a static mixer in a downstream flow direction from the actuator and in a upstream flow direction from the catheter lumen for mixing the first and second fluid compositions prior to passage through the catheter lumen.
Claim 2
Dependent Claim 224 words
An assembly for introducing a closure material to seal a puncture site in a vessel, the closure material comprising a mixture of a first and a second fluid composition, the assembly comprising a catheter having a proximal end and a distal end; at least one fluid delivery port adjacent the catheter distal end to occupy a position outside the vessel adjacent the puncture site; an expandable member distal to the fluid delivery port to extend through the puncture site and occupy a position inside the vessel while the at least one fluid delivery port occupies a position adjacent the vessel puncture site outside the vessel; a fluid delivery lumen in the catheter in fluid communication with the fluid delivery port; a guidewire lumen in the catheter sized to accommodate passage of a guide wire; one or more dispensers adjacent the catheter proximal end in fluid communication with the catheter lumen for dispensing the first and second fluid compositions into the catheter lumen; an actuator for causing the first and second fluid compositions to be dispensed from the one or more dispensers for passage through the catheter lumen; and a static mixer in a downstream flow direction from the actuator and in a upstream flow direction from the catheter lumen for mixing the first and second fluid compositions prior to passage through the catheter lumen.
Claim 3
Dependent Claim 13 words
An assembly as in claim 1 wherein the static mixer is a cartridge.
Claim 4
Dependent Claim 15 words
An assembly as in claim 1 wherein the static mixer is incorporated into the catheter.
Claim 5
Dependent Claim 15 words
An assembly as in claim 1 wherein the guidewire lumen extends through the static mixer.
Claim 6
Dependent Claim 170 words
An assembly for introducing a closure material to seal a vessel puncture site, the closure material comprising a mixture of a first and second fluid composition which, upon mixing, react to form a nonfluent closure composition, the assembly comprising a catheter for passage through a tissue puncture and having a distal end; at least one fluid delivery port adjacent the catheter distal end to occupy a position adjacent the vessel puncture site; a lumen in the catheter in fluid communication with the fluid delivery port, one or more dispensers in fluid communication with the catheter lumen for dispensing the first and second fluid compositions in the catheter lumen, and an actuator for causing the first and second fluid compositions to be dispensed from the one or more dispensers mixed by flowing the first and second fluid compositions through a static mixer within the lumen and dispensed from the fluid delivery port as a fluid mixture that reacts in situ to form the nonfluent closure composition adjacent the vessel puncture site.
Claim 7
Dependent Claim 170 words
An assembly for introducing a closure material to seal a vessel puncture site, the closure material comprising a mixture of a first and second fluid composition which, upon mixing, react to form a nonfluent closure composition, the assembly comprising a catheter for passage through a tissue puncture and having a distal end; at least one fluid delivery port adjacent the catheter distal end to occupy a position adjacent the vessel puncture site; a lumen in the catheter in fluid communication with the fluid delivery port, one or more dispensers in fluid communication with the catheter lumen for dispensing the first and second fluid compositions in the catheter lumen, and an actuator for causing the first and second fluid compositions to be dispensed from the one or more dispensers mixed by flowing the first and second fluid compositions through a static mixer within the lumen and dispensed from the fluid delivery port as a fluid mixture that reacts in situ to form the nonfluent closure composition adjacent the vessel puncture site.
Claim 8
Dependent Claim 16 words
An assembly as in claim 5 , wherein the static mixer is incorporated into the catheter.
Claim 9
Dependent Claim 14 words
An assembly as in claim 5 , wherein the static mixer is a cartridge.
Claim 10
Dependent Claim 186 words
An assembly for introducing a closure material to seal a vessel puncture site, the closure material comprising a mixture of a first and a second fluid composition which, upon mixing, react to form a nonfluent closure composition, the assembly comprising a catheter for passage through a tissue puncture and having a distal end; at least one fluid delivery port adjacent the catheter distal end to occupy a position adjacent the vessel puncture site; a lumen in the catheter in fluid communication with the fluid delivery port; one or more dispensers in fluid communication with the catheter lumen for dispensing the first and second fluid compositions into the catheter lumen; an actuator for causing the first and second fluid compositions to be dispensed from the one or more dispensers into the catheter lumen; and a static mixer communicating with the catheter lumen and capable of mixing the first and second fluid compositions within the catheter lumen, the first and second compositions being dispensed from the fluid delivery port as a fluid mixture that reacts in situ to form the nonfluent closure composition adjacent the vessel puncture site.
Claim 11
Dependent Claim 186 words
An assembly for introducing a closure material to seal a vessel puncture site, the closure material comprising a mixture of a first and a second fluid composition which, upon mixing, react to form a nonfluent closure composition, the assembly comprising a catheter for passage through a tissue puncture and having a distal end; at least one fluid delivery port adjacent the catheter distal end to occupy a position adjacent the vessel puncture site; a lumen in the catheter in fluid communication with the fluid delivery port; one or more dispensers in fluid communication with the catheter lumen for dispensing the first and second fluid compositions into the catheter lumen; an actuator for causing the first and second fluid compositions to be dispensed from the one or more dispensers into the catheter lumen; and a static mixer communicating with the catheter lumen and capable of mixing the first and second fluid compositions within the catheter lumen, the first and second compositions being dispensed from the fluid delivery port as a fluid mixture that reacts in situ to form the nonfluent closure composition adjacent the vessel puncture site.
Claim 12
Dependent Claim 15 words
The closure device of claim 8 wherein the static mixer is incorporated into the catheter.
Claim 13
Dependent Claim 13 words
The closure device of claim 8 wherein the static mixer is a cartridge.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2007-06-01 2007-12-01 2008-06-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2011-06-01 2011-12-01 2012-06-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2015-06-01 2015-12-01 2016-06-01 $7700.00 Window Closed / Lapsed

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