Patent US5856367A successfully refreshed from Google Patents.
US5856367A
Expired / Lapsed
US
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Biocompatible porous matrix of bioabsorbable material
Assignee: NeoMend Inc
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Filing: 1995-12-19
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Granted: 1999-01-05
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Expires: 2015-12-19
Abstract
Abstract A process for forming biocompatible porous matrices of bioabsorbable materials comprising: a) providing a bioabsorbable polymer; b) dissolving the bioabsorbable polymer in a volumetric orientation aid to yield a molten solution; c) solidifying the molten solution to yield an orientation matrix comprising first and second phases, the first phase being the bioabsorbable polymer and the second phase being the volumetric orientation aid; and d) removing the volumetric orientation aid while the solution is solid; to yield a biocompatible matrix of bioabsorbable polymer. Also matrices formed by the process and devices made with such matrices.
Inventors
- 👤 Thomas H. Barrows
- 👤 Myhanh T. Truong
- 👤 Paul R. Suszko
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 22:56
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/56; A61L27/14; A61L27/18; C; C08; C08L; C08L67/00; C08L67/04; Y; Y10; Y10S; Y10S977/00; Y10S977/70; Y10S977/788; Y10S977/795
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
85 words
A biocompatible porous matrix of bioabsorbable polymer made according to the following process: a) providing a bioabsorbable polymer; b) dissolving said bioabsorbable polymer in a volumetric orientation aid to yield a molten solution; c) solidifying said molten solution to yield an orientation matrix comprising first and second phases, said first phase being said bioabsorbable polymer and said second phase being said volumetric orientation aid; and d) then after said solidifying removing said volumetric orientation aid from said solid orientation matrix; to yield said biocompatible matrix.
Claim 2
Dependent Claim
85 words
A biocompatible porous matrix of bioabsorbable polymer made according to the following process: a) providing a bioabsorbable polymer; b) dissolving said bioabsorbable polymer in a volumetric orientation aid to yield a molten solution; c) solidifying said molten solution to yield an orientation matrix comprising first and second phases, said first phase being said bioabsorbable polymer and said second phase being said volumetric orientation aid; and d) then after said solidifying removing said volumetric orientation aid from said solid orientation matrix; to yield said biocompatible matrix.
Claim 3
Dependent Claim
22 words
The matrix of claim 1 wherein said matrix has a network of interconnecting pores and is compressible and resilient in some directions.
Claim 4
Dependent Claim
15 words
The matrix of claim 1 wherein said bioabsorbable polymer is a solid at 37° C.
Claim 5
Dependent Claim
35 words
The matrix of claim 1 wherein said bioabsorbable polymer comprises one or more of the following: polylactic acid, polyglycolic acid, polydioxanone, poly(lactide-co-glycolide), poly(trimethylene carbonate), polyesteramide, polycaprolactone, copolymer of such polymers, or mixture of such polymers.
Claim 6
Dependent Claim
17 words
The matrix of claim 2 wherein said matrix has a void volume of at least 20 percent.
Claim 7
Dependent Claim
19 words
The matrix of claim 2 wherein said matrix has a void volume between about 20 and about 97 percent.
Claim 8
Dependent Claim
20 words
The matrix of claim 2 wherein said pores have an average diameter of from about 0.5 to about 50 microns.
Claim 9
Dependent Claim
48 words
The matrix of claim 2 wherein said matrix has two arrays of pores, one said array being pores having an average diameter between about 0.5 and about 50 microns and the other said array being pores having an average diameter of between about 300 and about 500 microns.
Claim 10
Dependent Claim
34 words
The matrix of claim 2 wherein said matrix is in the form of one or more of the following: a fiber, a rod, a tube, a block, a woven fabric, or a nonwoven fabric.
Claim 11
Dependent Claim
22 words
The matrix of claim 1 wherein said solidifying of said molten solution is done by reducing the temperature of said molten solution.
Claim 12
Dependent Claim
24 words
The matrix of claim 1 wherein said removing said volumetric orientation aid from said solid orientation matrix is done by leaching with a solvent.
Claim 13
Dependent Claim
21 words
The matrix of claim 1 wherein said removing said volumetric orientation aid from said solid orientation matrix is done by sublimation.
Claim 14
Dependent Claim
19 words
The matrix of claim 1 wherein said matrix has been soaked in a plasticizing solution comprising plasticizer and solvent.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-01-04 | 2002-07-06 | 2003-01-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-01-04 | 2006-07-06 | 2007-01-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-01-04 | 2010-07-06 | 2011-01-05 | $7700.00 | Window Closed / Lapsed |