Biodegradable in-situ forming implants and method of producing the same
Abstract
Abstract A biodegradable thermosetting polymer system is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to form the implant in-situ. The thermosetting system comprises mixing together effective amounts of a liquid acrylic ester terminated, biodegradable prepolymer and a curing agent, placing the liquid mixture within an animal and allowing the prepolymer to cure to form the implant. The system provides a syringeable, solid biodegradable delivery system by the addition of an effective level of biologically active agent to the liquid before injection into the body. <IMAGE> <IMAGE>
Inventors
- 👤 Richard L Dunn
- 👤 James P English
- 👤 Donald R Cowsar
- 👤 David P Vanderbilt
Bibliographic Details
Claims Analysis
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