US5634946A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polymeric endoluminal paving process
Assignee: Endoluminal Therapeutics Inc
•
Filing: 1995-06-07
•
Granted: 1997-06-03
•
Expires: 2015-06-07
Abstract
Abstract A method for applying a paving material to a tissue surface is described. The method involves positioning a non-fluent polymeric material at the surface to be paved, rendering the material fluent, contacting the fluent polymer with the tissue surface, and allowing the polymer to return to its non-fluent condition.
Inventors
- 👤 Marvin J. Slepian
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:21
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2/062; A61F2/82; A61F2/86; A61F2/88; A61F2/95; A61F2/958; A61L; A61L24/00; A61L24/001; A61L24/0015; A61L24/0031; A61L24/0042; A61L24/04; A61L24/046; A61L24/06; A61L27/00; A61L27/14; A61L27/16; A61L27/28; A61L27/34; A61L27/50; A61L27/52; A61L27/54; A61L27/58; A61M; A61M25/00; A61M25/0043; A61M25/10; A61M25/1011; A61M25/104; A61F2210/00; A61F2210/0004; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/20; A61L2300/252; A61L2300/256; A61L2300/258; A61L2300/40; A61L2300/41; A61L2300/412; A61L2300/414; A61L2300/416; A61L2300/42; A61M2025/1043; A61M2025/1052; Y; Y10; Y10S; Y10S977/00; Y10S977/70; Y10S977/773; Y10S977/788; Y10S977/795
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
84 words
A method for forming a biocompatible polymer coating on a tissue surface of a lumen in a body vessel or hollow organ which comprises the steps of: a) providing a biocompatible polymeric material which is non-fluent at body temperature and which is fluent at an elevated temperature; b) heating the material to render the polymer fluent; c) contacting the fluent polymer with a surface to be coated; and d) allowing the fluent polymer to cool into a non-fluent biocompatible polymeric coating on the surface.
Claim 2
Independent Claim
84 words
A method for forming a biocompatible polymer coating on a tissue surface of a lumen in a body vessel or hollow organ which comprises the steps of: a) providing a biocompatible polymeric material which is non-fluent at body temperature and which is fluent at an elevated temperature; b) heating the material to render the polymer fluent; c) contacting the fluent polymer with a surface to be coated; and d) allowing the fluent polymer to cool into a non-fluent biocompatible polymeric coating on the surface.
Claim 3
Dependent Claim
12 words
A method as in claim 1 wherein the polymeric coating is biodegradable.
Claim 4
Dependent Claim
16 words
A method as in claim 2 wherein the biodegradable polymeric coating further includes a therapeutic agent.
Claim 5
Dependent Claim
45 words
A method as in claim 3 wherein the therapeutic agent is selected from the group consisting of anti-thrombotic agents, thrombolytic agents, vasodilating agents, anti-proliferative agents, intercalating agents, growth modulating factors, monoclonal antibodies, anti-inflammatory agents, lipid and cholesterol sequestrants, antisense oligonucleotides, ribozymes, aptomers and combinations thereof.
Claim 6
Dependent Claim
45 words
A method as in claim 1 wherein the biocompatible polymer is selected from the group consisting of polymers and copolymers of hydroxycarboxylic acids, polyurethanes, polyesters, polyamides, polyacrylonitriles, polyphosphazenes, polylactones, polyanhydrides, polyethylenes, polyalkysulfones, polycarbonates, polyhydroxybutyrates, polyhydroxyvalerates, hydrocarbon polymers, polypropylenes polyvinylchlorides, ethylene vinyl acetates and combinations thereof.
Claim 7
Dependent Claim
20 words
A method as in claim 1 wherein the polymeric coating has a thickness in the range of approximately 0.001-1.0 mm.
Claim 8
Dependent Claim
17 words
A method as in claim 1 wherein the tissue surface comprises a lumen in a body vessel.
Claim 9
Dependent Claim
14 words
A method as in claim 1 wherein the body vessel comprises a blood vessel.
Claim 10
Dependent Claim
14 words
A method as in claim 1 wherein the coating comprises a substantially continuous layer.
Claim 11
Dependent Claim
12 words
A method as in claim 9 wherein the continuous layer includes perforations.
Claim 12
Dependent Claim
24 words
A method as in claim 1 wherein the coating comprises a plurality of isolated coating domains, the domains comprising stellate, amorphous or spot geometries.
Claim 13
Dependent Claim
18 words
A method as in claim 1 wherein the coating portion opposite the tissue contacting surface is substantially smooth.
Claim 14
Independent Claim
89 words
A method for forming a biocompatible polymer coating on a tissue surface of a lumen in a body vessel or a hollow organ which comprises the steps of: a) providing a biocompatible polymeric material having a variable degree of fluency in response to a stimulus; b) providing the stimulus to the material to render the polymer fluent; c) contacting the fluent polymer with a surface to be coated; and d) allowing the fluent polymer to return to a non-fluent state, thereby providing a biocompatible polymeric coating on the surface.
Claim 15
Independent Claim
89 words
A method for forming a biocompatible polymer coating on a tissue surface of a lumen in a body vessel or a hollow organ which comprises the steps of: a) providing a biocompatible polymeric material having a variable degree of fluency in response to a stimulus; b) providing the stimulus to the material to render the polymer fluent; c) contacting the fluent polymer with a surface to be coated; and d) allowing the fluent polymer to return to a non-fluent state, thereby providing a biocompatible polymeric coating on the surface.
Claim 16
Dependent Claim
12 words
A method as in claim 13, wherein the polymeric coating is biodegradable.
Claim 17
Dependent Claim
16 words
A method as in claim 13, wherein the biodegradable polymeric coating further includes a therapeutic agent.
Claim 18
Dependent Claim
14 words
A method as in claim 13 wherein the body vessel comprises a blood vessel.
Claim 19
Independent Claim
83 words
A method for forming a biocompatible polymer coating on a tissue surface which comprises the steps of: a) providing a biocompatible polymeric material which is non-fluent at body temperature and which is fluent at an elevated temperature; b) heating the material to render the polymer fluent; c) contacting the fluent polymer with a surface to be coated; and d) allowing the fluent polymer to cool into a non-fluent biocompatible polymeric coating on the surface, the coating defining a passageway open to fluid flow.
Claim 20
Independent Claim
83 words
A method for forming a biocompatible polymer coating on a tissue surface which comprises the steps of: a) providing a biocompatible polymeric material which is non-fluent at body temperature and which is fluent at an elevated temperature; b) heating the material to render the polymer fluent; c) contacting the fluent polymer with a surface to be coated; and d) allowing the fluent polymer to cool into a non-fluent biocompatible polymeric coating on the surface, the coating defining a passageway open to fluid flow.
Claim 21
Dependent Claim
12 words
A method as in claim 17 wherein the polymeric coating is biodegradable.
Claim 22
Dependent Claim
16 words
A method as in claim 17 wherein the biodegradable polymeric coating further includes a therapeutic agent.
Claim 23
Dependent Claim
20 words
A method as in claim 17 wherein the tissue surface comprises a lumen in a body vessel or hollow organ.
Claim 24
Dependent Claim
14 words
A method as in claim 17 wherein the body vessel comprises a blood vessel.
References Cited (Backward Citations)
US2642874A
Cited
US2854982A
Cited
US3221745A
Cited
US3620218A
Cited
US3707146A
Cited
US3640741A
Cited
US3868956A
Cited
US3987000A
Cited
US4080969A
Cited
US3880158A
Cited
US4023559A
Cited
US4459252A
Cited
US4118470A
Cited
US4140126A
Cited
DE2827450A1
Cited
US4156067A
Cited
US4200939A
Cited
US4900303A
Cited
US4588395A
Cited
US4319363A
Cited
US4292299A
Cited
US4377010A
Cited
US4286341A
Cited
US4272518A
Cited
US4578061A
Cited
US4520823A
Cited
US4553545A
Cited
US4610662A
Cited
US4573966A
Cited
US4448188A
Cited
US4423725A
Cited
US4636195A
Cited
US4655771A
Cited
US4655771B1
Cited
US4445892A
Cited
US4443430A
Cited
US4503569A
Cited
US4643734A
Cited
US4603695A
Cited
US4733664A
Cited
US4655777A
Cited
EP0149693B1
Cited
US5124103A
Cited
US4701509A
Cited
US4580568A
Cited
EP0177330B1
Cited
EP0183372A1
Cited
US4799479A
Cited
US4575373A
Cited
US4674506A
Cited
US4595713A
Cited
US4763653A
Cited
US4923470A
Cited
EP0202444B1
Cited
US4711777A
Cited
US4690684A
Cited
US4781677A
Cited
US4776349A
Cited
US4650466A
Cited
US4776337A
Cited
US4733665B1
Cited
US4739762B1
Cited
US4776337B1
Cited
US4733665C2
Cited
US4733665A
Cited
US4739762A
Cited
US4702917A
Cited
DE3640745A1
Cited
US4655746A
Cited
US4763538A
Cited
US4832688A
Cited
US4709698A
Cited
EP0246638A3
Cited
EP0248246B1
Cited
US4754752A
Cited
US4763654A
Cited
US4744366A
Cited
US4740207A
Cited
US4841968A
Cited
US4771777A
Cited
US5037427A
Cited
US5306286A
Cited
US5059211A
Cited
US5175000A
Cited
US5395615A
Cited
US4969890A
Cited
US4790819A
Cited
US4820298A
Cited
US5192307A
Cited
US5145945A
Cited
US4853224A
Cited
US4870966A
Cited
US5181903A
Cited
US5080893A
Cited
US5232444A
Cited
US5068220A
Cited
US4950735A
Cited
US5213580A
Cited
US5278201A
Cited
US4938763A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-06-02 | 2000-12-02 | 2001-06-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-06-02 | 2004-12-02 | 2005-06-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-06-02 | 2008-12-02 | 2009-06-03 | $7700.00 | Window Closed / Lapsed |