US4603695A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of molded polymeric material for preventing adhesion of vital tissues
Assignee: JMS Co Ltd
•
Filing: 1984-06-29
•
Granted: 1986-08-05
•
Expires: 2004-06-29
Abstract
Abstract An adhesion preventive for preventing adhesion between vital tissues is provided. The present adhesion preventive is a molded material consisting essentially of a biodegradable and absorbable polymer. It has an advantage of requiring no reoperation for its removal since it would be degraded and absorbed after completing its function in vivo.
Inventors
- 👤 Yoshito Ikada
- 👤 Shokyu Gen
- 👤 Yasuhiko Shimizu
- 👤 Koichi Tamura
- 👤 Tatsuo Nakamura
- 👤 Sosuke Kimura
- 👤 Tsuneo Cho
- 👤 Hideki Tadokoro
- 👤 Kazuaki Hori
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 12:00
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/0063; A61L; A61L27/00; A61L27/50; A61L27/58; A61B; A61B90/00; A61B90/08; A61B2090/0815; A61B2090/0816; A61F2210/00; A61F2210/0004
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
196 words
A method for preventing adhesion between vital tissues which comprises placing between said tissues a molded material consisting essentially of a biodegradable and absorbable polymer selected from the group consisting of a polyester having repeating units of the formula: ##STR2## in which R 1 represents a C 1 to C 10 divalent alkylene group, a polyester having repeating units of the formula: ##STR3## in which each of R 2 and R 3 represents a C 1 to C 10 divalent alkylene group, a polyester having repeating units of the formula: ##STR4## in which each of R 4 , R 5 , and R 6 represents hydrogen or a lower alkyl group, and R 7 represents OR 7 ' or NR 7 "R 7 '" in which each of R 7 ', R 7 " and R 7 '" represents hydrogen or a lower alkyl group, a polyester having repeating units of the formula: ##STR5## in which R 8 represents a C 1 to C 10 divalent alkylene group, and each of R 9 , R 10 , R 11 and R 12 represents hydrogen or a lower alkyl group, collagen, an amino acid polymer or chitin.
Claim 2
Independent Claim
196 words
A method for preventing adhesion between vital tissues which comprises placing between said tissues a molded material consisting essentially of a biodegradable and absorbable polymer selected from the group consisting of a polyester having repeating units of the formula: ##STR2## in which R 1 represents a C 1 to C 10 divalent alkylene group, a polyester having repeating units of the formula: ##STR3## in which each of R 2 and R 3 represents a C 1 to C 10 divalent alkylene group, a polyester having repeating units of the formula: ##STR4## in which each of R 4 , R 5 , and R 6 represents hydrogen or a lower alkyl group, and R 7 represents OR 7 ' or NR 7 "R 7 '" in which each of R 7 ', R 7 " and R 7 '" represents hydrogen or a lower alkyl group, a polyester having repeating units of the formula: ##STR5## in which R 8 represents a C 1 to C 10 divalent alkylene group, and each of R 9 , R 10 , R 11 and R 12 represents hydrogen or a lower alkyl group, collagen, an amino acid polymer or chitin.
Claim 3
Dependent Claim
20 words
A method according to claim 1 in which the polymer is a polyester having repeating units of the formula: ##STR6##
Claim 4
Dependent Claim
15 words
A method according to claim 2 in which the polyester is a lactic acid homopolymer.
Claim 5
Dependent Claim
14 words
A method according to claim 2 in which the polyester is a lactic copolymer.
Claim 6
Dependent Claim
19 words
A method according to claim 4 in which the polyester is a copolymer of lactic acid and glycolic acid.
Claim 7
Dependent Claim
21 words
A method according to claim 4 in which a lactic acid copolymer contains at least 50 mole % of lactic acid.
Claim 8
Dependent Claim
20 words
A method according to claim 1 in which the polymer is a polyester having repeating units of the formula: ##STR7##
Claim 9
Dependent Claim
19 words
A method according to claim 7 in which the polyester is a homopolymer or a copolymer of a p-dioxanone.
Claim 10
Dependent Claim
20 words
A method according to claim 1 in which the polymer is a polyester having repeating units of the formula: ##STR8##
Claim 11
Dependent Claim
20 words
A method according to claim 1 in which the polymer is a polyester having repeating units of the formula: ##STR9##
Claim 12
Dependent Claim
12 words
A method according to claim 1 in which the polymer is collagen.
Claim 13
Dependent Claim
15 words
A method according to claim 1 in which the polymer is an amino acid polymer.
Claim 14
Dependent Claim
12 words
A method according to claim 1 in which the polymer is chitin.
Claim 15
Dependent Claim
18 words
A method according to claim 1 in which the molded material is in the form of a sheet.
Claim 16
Dependent Claim
18 words
A method according to claim 14 in which the sheet is from 10 to 1,000 microns in thickness.
Claim 17
Dependent Claim
12 words
A method according to claim 14 in which the sheet is non-porous.
Claim 18
Dependent Claim
12 words
A method according to claim 14 in which the sheet is porous.
Claim 19
Dependent Claim
16 words
A method according to claim 14 in which the sheet is a fabric or a knit.
Claim 20
Dependent Claim
19 words
A method according to claim 1 in which the polymer has a molecular weight of from 1,000 to 1,000,000.
Claim 21
Dependent Claim
32 words
A method according to claim 1 in which the polymer has a half-life period by weight ranging from seven days to one year as the result of degradation and absorption in vivo.
References Cited (Backward Citations)
US3739773A
Cited
US3875937A
Cited
US3797499A
Cited
US3883901A
Cited
US4032993A
Cited
US4208511A
Cited
US4343931A
Cited
US4490326A
Cited
US4429080A
Cited
US4523591A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-08-04 | 1990-02-03 | 1990-08-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-08-04 | 1994-02-03 | 1994-08-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-08-04 | 1998-02-03 | 1998-08-05 | $7700.00 | Window Closed / Lapsed |