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Compositions for treating hypercholesterolemia

Assignee: Procter and Gamble Co
•
Filing: 1991-09-30
•
Granted: 1992-05-26
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Expires: 2011-09-30
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Abstract

Abstract Cholestyramine and polyol polyesters are administered orally to reduce blood cholesterol levels.

Inventors

  • 👤 Charles D. Broaddus

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 19:15
CPC Classifications
A; A61; A61K; A61K36/00; A61K36/18; A61K36/185; A61K36/28; A61K36/286; A61K31/00; A61K31/74; A61K31/785; A61K36/13; A61K36/15; A61K36/31; A61K36/48; A61K36/63; A61K36/88; A61K36/889; A61K36/899

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 19 words
A composition of matter for reducing blood cholesterol levels, comprising: a) cholestyramine; and b) a nonabsorbable, nondigestible polyol polyester.
Claim 2
Dependent Claim 19 words
A composition of matter for reducing blood cholesterol levels, comprising: a) cholestyramine; and b) a nonabsorbable, nondigestible polyol polyester.
Claim 3
Dependent Claim 22 words
A composition according to claim 1 wherein the polyol polyester component (b) is sucrose octaoleate, sucrose octalinoleate, sucrose octapalmitate, and mixtures thereof.
Claim 4
Dependent Claim 18 words
A composition according to claim 2 wherein the weight ratio of component (a):component (b) is 3:1 to 1:3.
Claim 5
Dependent Claim 12 words
A composition according to claim 1 which is fortified with fat-soluble vitamins.
Claim 6
Independent Claim 42 words
A method for reducing blood cholesterol in a patient in need of such treatment, comprising orally administering to said patient a safe and effective amount of: a) cholestyramine; and b) a nonabsorbable, nondigestible polyol polyester; or c) mixtures of (a) and (b).
Claim 7
Independent Claim 42 words
A method for reducing blood cholesterol in a patient in need of such treatment, comprising orally administering to said patient a safe and effective amount of: a) cholestyramine; and b) a nonabsorbable, nondigestible polyol polyester; or c) mixtures of (a) and (b).
Claim 8
Dependent Claim 30 words
A method according to claim 5 which comprises oral ingestion of from 10 g to 40 g of component (a) and from 5 g to 50 g of component (b).
Claim 9
Dependent Claim 10 words
A method according to claim 6 which comprises chronic ingestion.
Claim 10
Dependent Claim 10 words
A method according to claim 7 which comprises daily ingestion.
Claim 11
Dependent Claim 47 words
A method according to claim 8 which comprises daily ingestion of from about 12 g to about 32 g of component (a) and from about 15 g to about 50 g of component (b), said ingestion being at two, three or four regularly-spaced intervals throughout the day.
Claim 12
Dependent Claim 20 words
A method according to claim 5 wherein the polyol polyester is sucrose octaoleate, sucrose octalinoleate, sucrose octapalmitate, and mixtures thereof.
Claim 13
Dependent Claim 17 words
A method according to claim 5 which includes the administration of fat-soluble vitamins in the treatment composition.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-05-26 1995-11-25 1996-05-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-05-26 1999-11-25 2000-05-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-05-26 2003-11-25 2004-05-26 $7700.00 Window Closed / Lapsed

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