Patent US4040421A successfully refreshed from Google Patents.
US3923972A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of lowering blood cholesterol level
Assignee: Monsanto Co
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Filing: 1973-04-23
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Granted: 1975-12-02
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Expires: 1993-04-23
Abstract
Abstract The level of blood cholesterol in a living animal body in which a state of hypercholesterolemia exists is lowered by orally administering to said animal body a pharmaceutically effective amount of a polymer, which is (1) polymerized unsaturated carboxylic acid or anhydride, or (2) a copolymer of (a) an unsaturated monomer having, for Example, 2 to 30 carbon atoms and, (b) an unsaturated carboxylic acid, anhydride or derivative thereof as exemplified by octadecene-1/maleic anhydride copolymer. Polymers having lipophilic properties are a preferred class. A typical dosage is an amount which represents in the range of from about 0.01 to about 5.0% of the diet.
Inventors
- 👤 Joseph E Fields
- 👤 John H Johnson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 20:56
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/74
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
76 words
A METHOD FOR LOWERING THE BLOOD CHOLESTEROL LEVEL IN A LIVING ANIMAL IN NEED THEREOF COMPRISING ORALLY ADMINISTERING TO SAID ANIMAL AN EFFECTIVE BLOOD CHOLESTEROL LOWERING AMOUNT OF A COPOLYMER OF (1) AN ALPHA ALKENE OF ABOUT 8 TO ABOUT 22 CARBON TOMS AND (2) MALEIC ACID OR ANHYDRIDE, OR A PHARMACEUTICALLY ACCEPTABLE AMIDE, ESTER, IMIDE, SALT THEREOF OR MIXTURES THEREOF, SAID COPOLYMER HAVING A MOLECULAR WEIGHT IN THE RANGE OF FROM ABOUT 1000 TO 1,000,000.
Claim 2
Independent Claim
76 words
A METHOD FOR LOWERING THE BLOOD CHOLESTEROL LEVEL IN A LIVING ANIMAL IN NEED THEREOF COMPRISING ORALLY ADMINISTERING TO SAID ANIMAL AN EFFECTIVE BLOOD CHOLESTEROL LOWERING AMOUNT OF A COPOLYMER OF (1) AN ALPHA ALKENE OF ABOUT 8 TO ABOUT 22 CARBON TOMS AND (2) MALEIC ACID OR ANHYDRIDE, OR A PHARMACEUTICALLY ACCEPTABLE AMIDE, ESTER, IMIDE, SALT THEREOF OR MIXTURES THEREOF, SAID COPOLYMER HAVING A MOLECULAR WEIGHT IN THE RANGE OF FROM ABOUT 1000 TO 1,000,000.
Claim 3
Dependent Claim
11 words
The method of claim 1 wherein the copolymer is octadecene-1/maleic anhydride.
Claim 4
Dependent Claim
11 words
The method of claim 1 wherein the copolymer is deCene-1/maleic anhydride.
Claim 5
Dependent Claim
11 words
The method of claim 1 wherein the copolymer is octadecene-1/maleic acid.
Claim 6
Dependent Claim
27 words
The method of claim 1 in which the copolymer is a lipophilic copolymer of an alpha-alkene of 10 to 22 carbon atoms and maleic acid or anhydride.
Claim 7
Dependent Claim
22 words
The method of claim 1 in which the copolymer is a polyelectrolyte copolymer of an alkene of 10 to 22 carbon atoms.
Claim 8
Dependent Claim
15 words
The method of claim 1 in which the alkene has 10 to 18 carbon atoms.
Claim 9
Dependent Claim
16 words
The method of claim 1 in which the maleic component of the copolymer is a mixture.
Claim 10
Dependent Claim
17 words
The method of claim 1 in which the copolymer is a copolymer of maleic acid or anhydride.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-12-01 | 1979-06-02 | 1979-12-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-12-01 | 1983-06-02 | 1983-12-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-12-01 | 1987-06-02 | 1987-12-02 | $7700.00 | Window Closed / Lapsed |