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US4898890A Expired / Lapsed US ⏱️ 0.0 years remaining

Medicines for use in the therapy and prevention of kidney and liver diseases

Assignee: DIC Corp
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Filing: 1987-06-22
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Granted: 1990-02-06
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Expires: 2007-06-22
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Abstract

Abstract A novel medicine containing isoliquiritigenin as the active ingredient is disclosed, which exhibits excellent effects when used as a medicine for the therapy and prevention of kidney diseases, a medicine for the therapy and prevention of liver diseases, and a medicine for the therapy and prevention of complication resulting from diseases of these organs.

Inventors

  • 👤 Toshio Sato
  • 👤 Hitoshi Matsumoto
  • 👤 Hisao Kakegawa

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-06 12:15
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/12

Claims Analysis

Total Claims: 53
Claim 1
Independent Claim 44 words
A method for the therapy and prevention of kidney diseases or liver diseases, comprising administering to a mammal a medicine containing a therapeutically or prophylactically effective amount for the therapy and prevention of kidney diseases, or liver diseases of isoliquiritigenin as an active ingredient.
Claim 2
Independent Claim 44 words
A method for the therapy and prevention of kidney diseases or liver diseases, comprising administering to a mammal a medicine containing a therapeutically or prophylactically effective amount for the therapy and prevention of kidney diseases, or liver diseases of isoliquiritigenin as an active ingredient.
Claim 3
Dependent Claim 17 words
The method according to claim 1, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 4
Dependent Claim 52 words
The method according to claim 2, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 5
Dependent Claim 56 words
The method according to claim 3, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 6
Dependent Claim 12 words
The method according to claim 1, wherein said diseases are kidney diseases.
Claim 7
Dependent Claim 17 words
The method according to claim 5, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 8
Dependent Claim 52 words
The method according to claim 6, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 9
Dependent Claim 56 words
The method according to claim 7, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 10
Dependent Claim 40 words
The method according to claim 5, wherein said kidney diseases are at least one of acute nephritis caused by a functional disorder of a kidney due to an abnormality in metabolic function, and chronic nephritis developed from said acute nephritis.
Claim 11
Dependent Claim 17 words
The method according to claim 9, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 12
Dependent Claim 52 words
The method according to claim 10, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 13
Dependent Claim 56 words
The method according to claim 11, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, an dispersing agent, a stabilizer and a colorant.
Claim 14
Dependent Claim 17 words
The method according to claim 9, wherein said abnormality in metabolic function is caused by a drug.
Claim 15
Dependent Claim 17 words
The method according to claim 13, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 16
Dependent Claim 52 words
The method according to claim 14, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 17
Dependent Claim 56 words
The method according to claim 15, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 18
Dependent Claim 43 words
The method according to claim 5, wherein said kidney diseases are at least one of a group of functional disorders of the kidney consisting of acute nephritis caused by the intermediary of the immunological mechanism, and chronic nephritis developed from said acute nephritis.
Claim 19
Dependent Claim 17 words
The method according to claim 17, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 20
Dependent Claim 52 words
The method according to claim 18, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 21
Dependent Claim 56 words
The method according to claim 19, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 22
Dependent Claim 41 words
The method according to claim 5, wherein said kidney diseases are at least one of a group of functional disorders of the kidney consisting of acute nephritis caused by bacteria and virus infection, and chronic nephritis developed from said acute nephritis.
Claim 23
Dependent Claim 17 words
The method according to claim 21, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 24
Dependent Claim 52 words
The method according to claim 22, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 25
Dependent Claim 56 words
The method according to claim 23, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 26
Dependent Claim 29 words
The method according to claim 1, wherein said kidney diseases are functional disorders of at least one kidney portion such as the glomerulus, the renal tubule, or the lupus.
Claim 27
Dependent Claim 17 words
The method according to claim 25, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 28
Dependent Claim 52 words
The method according to claim 26, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 29
Dependent Claim 56 words
The method according to claim 27, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 30
Dependent Claim 12 words
The method according to claim 1, wherein said diseases are liver diseases.
Claim 31
Dependent Claim 17 words
The method according to claim 29, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 32
Dependent Claim 52 words
The method according to claim 30, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 33
Dependent Claim 56 words
The method according to claim 31, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 34
Dependent Claim 27 words
The method according to claim 29, wherein said liver diseases are functional disorders of the liver caused by an abnormality in metabolic function and in biosynthetic function.
Claim 35
Dependent Claim 17 words
The method according to claim 33, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 36
Dependent Claim 52 words
The method according to claim 34, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 37
Dependent Claim 56 words
The method according to claim 35, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 38
Dependent Claim 23 words
The method according to claim 33, wherein said abnormality in the metabolic function and in the biosynthetic function is caused by a drug.
Claim 39
Dependent Claim 17 words
The method according to claim 37, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 40
Dependent Claim 52 words
The method according to claim 38, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 41
Dependent Claim 56 words
The method according to claim 39, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 42
Dependent Claim 20 words
The method according to claim 29, wherein said liver diseases are fatty liver or chronic hepatitis developed from fatty liver.
Claim 43
Dependent Claim 17 words
The method according to claim 41, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 44
Dependent Claim 52 words
The method according to claim 42, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 45
Dependent Claim 56 words
The method according to claim 43, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 46
Dependent Claim 24 words
The method according to claim 29, wherein said liver diseases are viral hepatitis caused by virus infection or chronic hepatitis developed from such hepatitis.
Claim 47
Dependent Claim 17 words
The method according to claim 45, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 48
Dependent Claim 52 words
The method according to claim 46, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 49
Dependent Claim 56 words
The method according to claim 47, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.
Claim 50
Dependent Claim 18 words
The method according to claim 1, wherein said diseases are complicated diseases of the kidney and the liver.
Claim 51
Dependent Claim 17 words
The method according to claim 49, wherein said medicine contains 0.1 to 100% by weight of isoliquiritigenin.
Claim 52
Dependent Claim 52 words
The method according to claim 50, wherein said medicine is in the form of a formulation selected from the group consisting of a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension and a syrup.
Claim 53
Dependent Claim 56 words
The method according to claim 51, wherein said medicine further contains at least one additive selected from the group consisting of an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer and a colorant.

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