US4091023A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dibenz[b,f]oxepin derivatives
Assignee: Hoffmann La Roche Inc
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Filing: 1977-03-18
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Granted: 1978-05-23
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Expires: 1997-03-18
Abstract
Abstract Dibenz[b,f]oxepins of the formula <IMAGE> I wherein R, R1, R2, R3 and R4 are as hereinafter described, are described. The foregoing compounds exhibit strong central depressant and neuroleptic properties, and are useful, for example, in the treatment of acute or chronic schizophrenia and also as tranquilizers.
Inventors
- 👤 Max Gerecke
- 👤 Emilio Kyburz
- 👤 Jean-Pierre Kaplan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 02:35
CPC Classifications
C; C07; C07D; C07D405/00; C07D405/02; C07D405/04; C07D313/00; C07D313/02; C07D313/06; C07D313/10; C07D313/14; C07D405/14; C07D413/00; C07D413/14
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
67 words
A compound of the formula ##STR19## wherein one of R 1 ' and R 2 ' is hydrogen and the other is halogen, lower alkyl, lower alkoxy, lower alkylthio, or trifluoromethyl; one of R 3 ' and R 4 ' is hydrogen and the other is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, or trifluoromethyl; and R 5 is lower alkanoyl, hydroxy-lower alkanoyl or lower alkoxycarbonyl.
Claim 2
Dependent Claim
67 words
A compound of the formula ##STR19## wherein one of R 1 ' and R 2 ' is hydrogen and the other is halogen, lower alkyl, lower alkoxy, lower alkylthio, or trifluoromethyl; one of R 3 ' and R 4 ' is hydrogen and the other is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, or trifluoromethyl; and R 5 is lower alkanoyl, hydroxy-lower alkanoyl or lower alkoxycarbonyl.
Claim 3
Dependent Claim
11 words
A compound in accordance with claim 1, 4-[10,11-dihydro-2,8-dimethyldibenz[b,f]oxepin-10-yl]-1-piperazine-carboxylic acid ethyl ester.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-05-22 | 1981-11-21 | 1982-05-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-05-22 | 1985-11-21 | 1986-05-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-05-22 | 1989-11-21 | 1990-05-23 | $7700.00 | Window Closed / Lapsed |