US4006145A
Expired / Lapsed
US
⏱️ 0.0 years remaining
10,11-Dihydro dibenzo(b,f)thiepin derivatives
Assignee: Hoffmann La Roche Inc
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Filing: 1975-10-03
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Granted: 1977-02-01
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Expires: 1995-10-03
Abstract
Abstract Dibenzothiepin derivatives of the general formula <IMAGE> wherein m, n, R1, R2, R3 and X are as hereinafter set forth, and salts thereof as well as processes for their manufacture are disclosed. The end products are useful as central-depressant and neuroleptic agents.
Inventors
- 👤 Max Gerecke
- 👤 Jean-Pierre Kaplan
- 👤 Emilio Kyburz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 20:58
CPC Classifications
C; C07; C07C; C07C323/00; C07D; C07D337/00; C07D337/02; C07D337/06; C07D337/10; C07D337/14
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
49 words
A compound of the formula ##STR12## wherein n is 2 or 3, R 1 is halogen, lower alkyl, di(lower alkyl)sulphamoyl nitro, amino, di(lower alkyl)amino or trifluoromethyl, X is methylene, m is 1 and R 2 and R 3 each is hydrogen or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
49 words
A compound of the formula ##STR12## wherein n is 2 or 3, R 1 is halogen, lower alkyl, di(lower alkyl)sulphamoyl nitro, amino, di(lower alkyl)amino or trifluoromethyl, X is methylene, m is 1 and R 2 and R 3 each is hydrogen or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
17 words
A compound in accordance with claim 1, 1-{2-[4(2-chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-1-piperazinyl]-ethyl }-2-piperidone, or a pharmaceutically acceptable acid addition salt thereof.
References Cited (Backward Citations)
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US3725409A
Cited
US3646037A
Cited
US3828046A
Cited
US3929791A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-02-01 | 1980-08-02 | 1981-02-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-02-01 | 1984-08-02 | 1985-02-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-02-01 | 1988-08-02 | 1989-02-01 | $7700.00 | Window Closed / Lapsed |