US7094230B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Systems and methods for delivering drugs to selected locations within the body
Assignee: Transvascular Inc
•
Filing: 2003-12-16
•
Granted: 2006-08-22
•
Expires: 2023-12-16
Abstract
Abstract An implantable reservoir device ( 400 ) including an enclosed membrane ( 408 ) on an expandable frame ( 402 ) that defines a reservoir ( 410 ) and includes a porous region ( 418 ). The reservoir device ( 400 ) may be deployed and expanded within a blood vessel, and may be filled in situ or prefilled with a drug that passes through the porous region ( 418 ). Alternatively, a pair of expandable endovascular blockers ( 500 ) may be used to isolate a section of a blood vessel which may be filled with a drug that may be absorbed by the surrounding tissue.
Inventors
- 👤 J. Christopher Flaherty
- 👤 Joshua Makower
- 👤 Philip C. Evard
- 👤 Patrick E. Macaulay
- 👤 Jason B. Whitt
- 👤 Robert C. Colloton
- 👤 K. Angela Macfarlane
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 19:25
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/0067; A61M25/0082; A61M25/0084; A61B; A61B17/00; A61B17/11; A61B17/12; A61B17/12022; A61B17/12027; A61B17/1204; A61B17/12045; A61B17/12099; A61B17/12109; A61B17/12131; A61B17/12136; A61B17/12168; A61B17/12172; A61B17/34; A61B17/3417; A61M25/0068; A61M25/01; A61M25/0105; A61M25/0108; A61M5/00; A61M5/007; A61M5/46; A61B17/00491; A61B17/064; A61B17/0643; A61B17/22; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1477; A61B18/1492; A61B17/00234; A61B2017/00238; A61B2017/00243; A61B2017/00247; A61B2017/00252; A61B2017/00504; A61B2017/1107; A61B2017/1139; A61B2017/12127; A61B2017/22072; A61B2017/22074; A61B2017/22077; A61B17/30; A61B2017/306; A61B2017/347; A61B2018/00315; A61B2018/00345; A61B2018/00351; A61B2018/00392; A61B2018/1405; A61B2018/1425; A61B8/00; A61B8/12; A61B90/00; A61B90/40; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2493; A61F2/30; A61F2002/30001; A61F2002/30003; A61F2002/3006; A61F2002/30079; A61F2210/00; A61F2210/009; A61M25/0021; A61M25/0023; A61M25/0026; A61M2025/0037; A61M25/0074; A61M25/0075; A61M2025/0076; A61M2025/0085; A61M2025/0086; A61M2025/0087; A61M2025/0089; A61M2025/009; A61M2025/0096; A61M25/10; A61M2025/1043; A61M2025/1052; A61M25/0069; A61M25/007; A61M39/00; A61M39/02; A61M39/0208; A61M39/04
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
164 words
A reservoir device for providing sustained delivery of a drug within the cardiovascular system of a patient, comprising: a substantially cylindrical frame adapted to expand between a collapsed condition for insertion into a blood vessel and an enlarged condition for engaging a wall of the blood vessel, the frame defining a longitudinal axis and a periphery; and a flexible membrane attached to the frame, the membrane including a generally cylindrical periphery with transversely disposed end panels attached to the periphery to define a generally cylindrical reservoir having closed ends, a porous region being disposed along at least a portion of the periphery of the flexible membrane such that drug that has been injected into the reservoir will pass out of the reservoir through said porous region at least one of said end panels being formed of material which can be penetrated by a hollow needle through which drug may be injected into the reservoir and which will automatically reseal after the needle is withdrawn.
Claim 2
Dependent Claim
164 words
A reservoir device for providing sustained delivery of a drug within the cardiovascular system of a patient, comprising: a substantially cylindrical frame adapted to expand between a collapsed condition for insertion into a blood vessel and an enlarged condition for engaging a wall of the blood vessel, the frame defining a longitudinal axis and a periphery; and a flexible membrane attached to the frame, the membrane including a generally cylindrical periphery with transversely disposed end panels attached to the periphery to define a generally cylindrical reservoir having closed ends, a porous region being disposed along at least a portion of the periphery of the flexible membrane such that drug that has been injected into the reservoir will pass out of the reservoir through said porous region at least one of said end panels being formed of material which can be penetrated by a hollow needle through which drug may be injected into the reservoir and which will automatically reseal after the needle is withdrawn.
Claim 3
Dependent Claim
13 words
The device of claim 1 , wherein the frame comprises a woven mesh.
Claim 4
Dependent Claim
15 words
The device of claim 1 , wherein the frame is biased towards the enlarged condition.
Claim 5
Dependent Claim
14 words
The device of claim 1 , wherein the porous region comprises a semi-permeable material.
Claim 6
Dependent Claim
23 words
The device of claim 1 , further comprising a drug within the reservoir adapted to pass through the porous region of the membrane.
Claim 7
Dependent Claim
14 words
The device of claim 5 , further comprising an anti-coagulant compound within the reservoir.
Claim 8
Dependent Claim
24 words
The device of claim 1 , wherein an end panel is penetrable by an injection device to facilitate in situ filling of the reservoir.
Claim 9
Dependent Claim
19 words
The device of claim 1 , further comprising a septum dividing the reservoir into first and second reservoir regions.
Claim 10
Dependent Claim
19 words
The device of claim 8 , wherein the membrane includes an osmotic region communicating with the first reservoir region.
Claim 11
Dependent Claim
19 words
The device of claim 9 , wherein the porous region of the membrane communicates with the second reservoir region.
References Cited (Backward Citations)
US1762858A
Cited
US3516408A
Cited
US3732865A
Cited
US4291013A
Cited
US4578061A
Cited
US4576604A
Cited
US4774949A
Cited
US5597378A
Cited
US5423878A
Cited
US4794931A
Cited
US5588432A
Cited
US4859470A
Cited
US5738658A
Cited
US5242397A
Cited
US5106386A
Cited
US4997431A
Cited
US5662609A
Cited
US5342394A
Cited
US5047039A
Cited
US5190528A
Cited
US5054492A
Cited
US5304121A
Cited
US5330496A
Cited
US5193546A
Cited
US5167239A
Cited
US5551954A
Cited
US5345940A
Cited
US5713363A
Cited
US5704361A
Cited
US5661133B1
Cited
US5661133A
Cited
US5554182A
Cited
US5254089A
Cited
US5282810A
Cited
US5599300A
Cited
US5336252A
Cited
US5507724A
Cited
US5538504A
Cited
US5366490A
Cited
US5312341A
Cited
US5570693A
Cited
US5354279A
Cited
US5287861A
Cited
US5409019A
Cited
US5429144A
Cited
US5609574A
Cited
US5571086A
Cited
US5807306A
Cited
US5373849A
Cited
US5452733A
Cited
US5523092A
Cited
US5462523A
Cited
US5932460A
Cited
US5713887A
Cited
US6004269A
Cited
US5429634A
Cited
US5499630A
Cited
US5443497A
Cited
US5397307A
Cited
US5628784A
Cited
US5419777A
Cited
US5536250A
Cited
US5464395A
Cited
US5772632A
Cited
US5634895A
Cited
US5554114A
Cited
US5571151A
Cited
US5707385A
Cited
US5704926A
Cited
US5588960A
Cited
US5569197A
Cited
US5614204A
Cited
US5665077A
Cited
US5728123A
Cited
US5596990A
Cited
US5724977A
Cited
US5713853A
Cited
US5674198A
Cited
US5693029A
Cited
US5735847A
Cited
US5607418A
Cited
US5772629A
Cited
US5771895A
Cited
US5707363A
Cited
US6171298B1
Cited
US20020062146A1
Cited
US6053911A
Cited
US5724975A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2009-08-21 | 2010-02-20 | 2010-08-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2013-08-21 | 2014-02-20 | 2014-08-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2017-08-21 | 2018-02-20 | 2018-08-22 | $7700.00 | Window Closed / Lapsed |