Patent US6203485B1 successfully refreshed from Google Patents.
US6203485B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Low attenuation guide wire for intravascular radiation delivery
Assignee: Boston Scientific Scimed Inc
•
Filing: 1999-10-07
•
Granted: 2001-03-20
•
Expires: 2019-10-07
Abstract
Abstract A low attenuation guide wire for use in combination with a radiation device for intravascular ionizing radiation therapy. The distal region of the guide wire is less attenuating to ionizing radiation than the proximal region and may be disposed adjacent the radiation emitting portion of the radiation device without significantly compromising the emission of radiation. Thus, the guide wire does not need to be removed or retracted in order to effectively deliver ionizing radiation to the vascular target site.
Inventors
- 👤 Michael J. Urick
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 19:28
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1002
Claims Analysis
Total Claims: 51
Claim 1
Independent Claim
35 words
A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region.
Claim 2
Dependent Claim
35 words
A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region.
Claim 3
Dependent Claim
56 words
A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal region and a distal region, wherein the distal region includes a proximal end portion and a distal end portion, the proximal end portion being relatively less attenuating to ionizing radiation, and the distal end portion being relatively more radiopaque.
Claim 4
Dependent Claim
56 words
A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal region and a distal region, wherein the distal region includes a proximal end portion and a distal end portion, the proximal end portion being relatively less attenuating to ionizing radiation, and the distal end portion being relatively more radiopaque.
Claim 5
Dependent Claim
26 words
A guide wire as in claim 2 , wherein the proximal end portion is less attenuating to low energy gamma ionizing radiation than the proximal region.
Claim 6
Dependent Claim
26 words
A guide wire as in claim 2 , wherein the proximal end portion is less attenuating to high energy gamma ionizing radiation than the proximal region.
Claim 7
Dependent Claim
24 words
A guide wire as in claim 2 , wherein the proximal end portion is less attenuating to beta ionizing radiation than the proximal region.
Claim 8
Dependent Claim
22 words
A guide wire as in claim 2 , wherein the proximal end portion has a lower atomic number than the proximal region.
Claim 9
Dependent Claim
21 words
A guide wire as in claim 6 , wherein the proximal end portion has an atomic number of less than 22.
Claim 10
Dependent Claim
21 words
A guide wire as in claim 6 , wherein the proximal end portion has an atomic number of less than 15.
Claim 11
Dependent Claim
21 words
A guide wire as in claim 6 , wherein the proximal end portion has an atomic number of less than 7.
Claim 12
Dependent Claim
22 words
A guide wire as in claim 2 , wherein the proximal end portion has a lower atomic weight than the proximal region.
Claim 13
Dependent Claim
21 words
A guide wire as in claim 10 , wherein the proximal end portion has an atomic weight of less than 47.
Claim 14
Dependent Claim
21 words
A guide wire as in claim 10 , wherein the proximal end portion has an atomic weight of less than 29.
Claim 15
Dependent Claim
21 words
A guide wire as in claim 10 , wherein the proximal end portion has an atomic weight of less than 13.
Claim 16
Dependent Claim
21 words
A guide wire as in claim 2 , wherein the proximal end portion has a lower density than the proximal region.
Claim 17
Dependent Claim
23 words
A guide wire as in claim 14 , wherein the proximal end portion has a density of less than 4.5 g/cm 3 .
Claim 18
Dependent Claim
23 words
A guide wire as in claim 14 , wherein the proximal end portion has a density of less than 2.3 g/cm 3 .
Claim 19
Dependent Claim
23 words
A guide wire as in claim 14 , wherein the proximal end portion has a density of less than 2.0 g/cm 3 .
Claim 20
Dependent Claim
15 words
A guide wire as in claim 2 , wherein the proximal end portion comprises graphite.
Claim 21
Dependent Claim
15 words
A guide wire as in claim 2 , wherein the proximal end portion comprises aluminum.
Claim 22
Dependent Claim
15 words
A guide wire as in claim 2 , wherein the proximal end portion comprises silicon.
Claim 23
Dependent Claim
16 words
A guide wire as in claim 2 , wherein the proximal end portion comprises a polymer.
Claim 24
Dependent Claim
17 words
A guide wire as in claim 2 , wherein the proximal end portion comprises a reinforced polymer.
Claim 25
Dependent Claim
21 words
A guide wire as in claim 2 , wherein the proximal end portion comprises a polymer reinforced with a metallic coil.
Claim 26
Dependent Claim
21 words
A guide wire as in claim 2 , wherein the proximal end portion comprises a polymer reinforced with a metallic braid.
Claim 27
Dependent Claim
20 words
A guide wire as in claim 2 , wherein the proximal end portion comprises a polymer reinforced with glass fibers.
Claim 28
Dependent Claim
16 words
A guide wire as in claim 2 , wherein the proximal end portion comprises a metal.
Claim 29
Dependent Claim
17 words
A guide wire as in claim 26 , wherein the proximal end portion comprises a metal alloy.
Claim 30
Dependent Claim
17 words
A guide wire as in claim 2 , wherein the proximal end portion comprises a single material.
Claim 31
Dependent Claim
18 words
A guide wire as in claim 2 , wherein the proximal end portion comprises a plurality of materials.
Claim 32
Dependent Claim
18 words
A guide wire as in claim 2 , wherein the proximal end portion comprises a composite of materials.
Claim 33
Independent Claim
61 words
A system for administering intravascular ionizing radiation therapy, comprising: an intravascular device having a distal portion emitting ionizing radiation; and a guide wire comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region, the distal region being disposed adjacent the distal portion of the intravascular device.
Claim 34
Independent Claim
61 words
A system for administering intravascular ionizing radiation therapy, comprising: an intravascular device having a distal portion emitting ionizing radiation; and a guide wire comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region, the distal region being disposed adjacent the distal portion of the intravascular device.
Claim 35
Dependent Claim
28 words
A system as in claim 31 , wherein the distal region of the guide wire is less attenuating to low energy gamma ionizing radiation than the proximal region.
Claim 36
Dependent Claim
28 words
A system as in claim 31 , wherein the distal region of the guide wire is less attenuating to high energy gamma ionizing radiation than the proximal region.
Claim 37
Dependent Claim
26 words
A system as in claim 31 , wherein the distal region of the guide wire is less attenuating to beta ionizing radiation than the proximal region.
Claim 38
Dependent Claim
24 words
A system as in claim 31 , wherein the distal region of the guide wire has a lower atomic number than the proximal region.
Claim 39
Dependent Claim
24 words
A system as in claim 31 , wherein the distal region of the guide wire has a lower atomic weight than the proximal region.
Claim 40
Dependent Claim
23 words
A system as in claim 31 , wherein the distal region of the guide wire has a lower density than the proximal region.
Claim 41
Dependent Claim
18 words
A system as in claim 31 , wherein the distal region of the guide wire comprises a polymer.
Claim 42
Dependent Claim
18 words
A system as in claim 31 , wherein the distal region of the guide wire comprises a metal.
Claim 43
Dependent Claim
19 words
A system as in claim 31 , wherein the distal region of the guide wire comprises a single material.
Claim 44
Dependent Claim
20 words
A system as in claim 31 , wherein the distal region of the guide wire comprises a plurality of materials.
Claim 45
Dependent Claim
20 words
A system as in claim 31 , wherein the distal region of the guide wire comprises a composite of materials.
Claim 46
Dependent Claim
51 words
A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal portion, a mid portion and a distal portion, the mid portion being less attenuating to ionizing radiation than the proximal and distal portions, and the distal portion being more radiopaque than the mid portion.
Claim 47
Dependent Claim
51 words
A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal portion, a mid portion and a distal portion, the mid portion being less attenuating to ionizing radiation than the proximal and distal portions, and the distal portion being more radiopaque than the mid portion.
Claim 48
Independent Claim
126 words
A method of administering intravascular ionizing radiation therapy to a treatment site in a patient's vascular system, the method comprising the steps of: providing an intravascular device having a distal portion emitting ionizing radiation; providing a guide wire comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region; advancing the guide wire through the patient's vascular system until the distal region is disposed adjacent the treatment site; and advancing the intravascular device through the patient's vascular system until the distal portion emitting ionizing radiation is disposed adjacent the treatment site whereby radiation emitted from the distal portion of the intravascular device traverses the less attenuating distal region of the guide wire.
Claim 49
Independent Claim
126 words
A method of administering intravascular ionizing radiation therapy to a treatment site in a patient's vascular system, the method comprising the steps of: providing an intravascular device having a distal portion emitting ionizing radiation; providing a guide wire comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region; advancing the guide wire through the patient's vascular system until the distal region is disposed adjacent the treatment site; and advancing the intravascular device through the patient's vascular system until the distal portion emitting ionizing radiation is disposed adjacent the treatment site whereby radiation emitted from the distal portion of the intravascular device traverses the less attenuating distal region of the guide wire.
Claim 50
Dependent Claim
63 words
A method of administering intravascular ionizing radiation therapy as in claim 44 , wherein the guide wire is disposed in a guide wire lumen contained at least partially in the intravascular device, and wherein the step of advancing the intravascular device comprises advancing the intravascular device over the guide wire until the distal portion emitting ionizing radiation is disposed adjacent the treatment site.
Claim 51
Dependent Claim
73 words
A method of administering intravascular ionizing radiation therapy as in claim 44 , wherein the intravascular device includes a centering catheter and a source wire having a distal portion emitting ionizing radiation, and wherein the step of advancing the intravascular device comprises advancing the centering catheter device over the guide wire and advancing the source wire in the centering catheter until the distal portion emitting ionizing radiation is disposed adjacent the treatment site.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2004-03-19 | 2004-09-18 | 2005-03-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2008-03-19 | 2008-09-18 | 2009-03-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2012-03-19 | 2012-09-18 | 2013-03-20 | $7700.00 | Window Closed / Lapsed |