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US5817075A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for preparation and transplantation of planar implants and surgical instrument therefor

Assignee: Photogenesis Inc
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Filing: 1995-02-28
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Granted: 1998-10-06
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Expires: 2015-02-28
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Abstract

Abstract A method for transplanting planar implants, devices, etc., is provided. Method is particularly adapted for transplanting planar sheets of retinal cells to the subretinal region of an eye. A method of preparing the retinal cell sheet and the associated surgical instrument is also provided.

Inventors

  • 👤 John Giungo

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 05:15
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/14; A61F2/148; A61M; A61M31/00; A61B; A61B17/00; A61B17/34; A61B17/3468; A61B90/00; A61F2/0095; A61F9/00; A61F9/007; A61F9/00736; A61F9/013; A61L; A61L27/00; A61L27/36; A61L27/38; A61L27/3804; A61L27/3813; A61L27/383; A61L27/3839; A61B17/0057; A61B2017/00969; A61L2430/00; A61L2430/16; A61M25/00; A61M25/0021; A61M2025/0042; A61M2210/00; A61M2210/06; A61M2210/0612; Y; Y10; Y10S; Y10S623/00; Y10S623/902; Y10S623/905

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 244 words
An instrument for the implantation of an implant in a host, comprising: a tubular body, and a first housing, said tubular body having a first end for receiving an implant and a second end for insertion in a host, said tubular body having a first conduit passing from said first end to said second end, wherein said tubular body is connected to said first housing, said first housing having a first end and a second end, said instrument further comprising: plunger means for expressing an implant contained within the instrument, said plunger means being at least partially contained within a second housing, and first means on said first housing for engagement with a storage container within which said tubular body and housing may be sealed, and second means on said first housing for locking engagement with said second housing wherein, when said first housing is in locking engagement with said second housing, said conduit in said first tubular body is aligned with said plunger means to permit said plunger means to extend into said conduit to provide expression of an implant contained within said tubular body by said plunger means, and at least one of said housings forms a handpiece for manipulation of said tubular body, wherein said plunger means comprises a cable member capable of relative movement inside of said conduit in said tubular body, the instrument also including electromechanical actuation means for advancing and retracting said cable member inside of said conduit.
Claim 2
Dependent Claim 244 words
An instrument for the implantation of an implant in a host, comprising: a tubular body, and a first housing, said tubular body having a first end for receiving an implant and a second end for insertion in a host, said tubular body having a first conduit passing from said first end to said second end, wherein said tubular body is connected to said first housing, said first housing having a first end and a second end, said instrument further comprising: plunger means for expressing an implant contained within the instrument, said plunger means being at least partially contained within a second housing, and first means on said first housing for engagement with a storage container within which said tubular body and housing may be sealed, and second means on said first housing for locking engagement with said second housing wherein, when said first housing is in locking engagement with said second housing, said conduit in said first tubular body is aligned with said plunger means to permit said plunger means to extend into said conduit to provide expression of an implant contained within said tubular body by said plunger means, and at least one of said housings forms a handpiece for manipulation of said tubular body, wherein said plunger means comprises a cable member capable of relative movement inside of said conduit in said tubular body, the instrument also including electromechanical actuation means for advancing and retracting said cable member inside of said conduit.
Claim 3
Dependent Claim 156 words
The instrument of claim 1, further including a container for said tubular body and said first housing, said container having an interior cavity into which said tubular body may be completely inserted, said interior cavity having surfaces, said container further having positioning means for engagement with said first means on said first housing for positioning said tubular body and said first housing in said container, wherein, when said tubular body is located within said interior of said container and said first means on said first housing is operably engaged with said positioning means, said tubular body will not contact said surfaces of said container, whereby an implant may be placed in said tubular body, and the instrument containing the implant sealed in said container with said first means on said first housing operably engaged with said positioning means, so that the implant and said tubular body will be protected in said container during storage and shipping.
Claim 4
Dependent Claim 37 words
The instrument of claim 2, wherein said second end of said tubular body may be inserted into the eye of a host to permit expression of an implant contained within said tubular body into the host eye.
Claim 5
Dependent Claim 35 words
The instrument of claim 3, wherein said second end of said tubular body may be inserted beneath the retina of a host eye to permit expression of said implant beneath the retina the host eye.
Claim 6
Dependent Claim 28 words
The instrument of claim 4, wherein said implant is a coiled planar implant, which, upon expression beneath the retina of a host eye, will at least partially uncoil.
Claim 7
Dependent Claim 33 words
The instrument of claim 2, further comprising an implant located within said tubular body, said implant comprising a substance selected from the group comprised of photoreceptor cells, retinal pigment epithelial cells, and drugs.
Claim 8
Dependent Claim 274 words
A kit for storing and transporting an implant loaded in an implanting instrument, comprising: a container, an instrument within said container, and an implant within said instrument, wherein: said instrument comprises a tubular body, and a first housing, said tubular body has a first end for receiving an implant and a second end for insertion in a host, and a first conduit passing from said first end to said second end, wherein said tubular body is connected to said first housing, and said implant is located within said tubular body, said first housing has first means for engagement with said container, said container having surfaces which form an interior cavity into which said tubular body may be completely inserted, said container further having positioning means for engagement with said first means on said first housing for positioning said tubular body and said first housing in said container, wherein, when said tubular body is located within said interior cavity of said container and said first means on said first housing is operably engaged with said positioning means, said tubular body will not contact said surfaces of said container, said implant comprises a substance selected from the group comprised of photoreceptor cells, retinal pigment epithelial cells, and drugs, and said first housing further comprises second means thereon for locking engagement with a second housing, whereby, when said second housing contains plunger means for expression of an implant contained within said tubular body and said first housing is in locking engagement the second housing, the plunger means can extend into said conduit in said tubular body to provide expression of an implant contained in said tubular body.
Claim 9
Dependent Claim 274 words
A kit for storing and transporting an implant loaded in an implanting instrument, comprising: a container, an instrument within said container, and an implant within said instrument, wherein: said instrument comprises a tubular body, and a first housing, said tubular body has a first end for receiving an implant and a second end for insertion in a host, and a first conduit passing from said first end to said second end, wherein said tubular body is connected to said first housing, and said implant is located within said tubular body, said first housing has first means for engagement with said container, said container having surfaces which form an interior cavity into which said tubular body may be completely inserted, said container further having positioning means for engagement with said first means on said first housing for positioning said tubular body and said first housing in said container, wherein, when said tubular body is located within said interior cavity of said container and said first means on said first housing is operably engaged with said positioning means, said tubular body will not contact said surfaces of said container, said implant comprises a substance selected from the group comprised of photoreceptor cells, retinal pigment epithelial cells, and drugs, and said first housing further comprises second means thereon for locking engagement with a second housing, whereby, when said second housing contains plunger means for expression of an implant contained within said tubular body and said first housing is in locking engagement the second housing, the plunger means can extend into said conduit in said tubular body to provide expression of an implant contained in said tubular body.
Claim 10
Dependent Claim 35 words
The instrument of claim 7, wherein said second end of said tubular body may be inserted beneath the retina of a host eye to permit expression of said implant beneath the retina the host eye.
Claim 11
Dependent Claim 28 words
The instrument of claim 8, wherein said implant is a coiled planar implant, which, upon expression beneath the retina of a host eye, will at least partially uncoil.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-10-05 2002-04-06 2002-10-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-10-05 2006-04-06 2006-10-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-10-05 2010-04-06 2010-10-06 $7700.00 Window Closed / Lapsed

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