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US5741323A Expired / Lapsed US ⏱️ 0.0 years remaining

Polymeric article for intraluminal photothermoforming

Assignee: Genzyme Corp
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Filing: 1995-06-07
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Granted: 1998-04-21
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Expires: 2015-06-07
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Abstract

Abstract A method and apparatus for molding polymeric structures in vivo is disclosed. The structures comprise polymers that may be heated to their molding temperature by absorption of visible or near-visible wavelengths of light. By providing a light source that produces radiation of the wavelength absorbed by the polymeric material, the material may be selectively heated and shaped in vivo without a corresponding heating of adjacent tissues or fluids to unacceptable levels. The apparatus comprises a catheter having a shaping element positioned near its distal end. An emitter provided with light from at least one optical fiber is positioned within the shaping element. The emitter serves to provide a moldable polymeric article positioned on the shaping element with a substantially uniform light field, thereby allowing the article to be heated and molded at a desired treatment site in a body lumen.

Inventors

  • 👤 Chandrashekhar P. Pathak
  • 👤 Amarpreet S. Sawhney
  • 👤 Jeffrey A. Hubbell
  • 👤 Stephen J. Herman
  • 👤 Laurence A. Roth
  • 👤 Patrick K. Campbell
  • 👤 Kevin M. Berrigan
  • 👤 Peter K. Jarrett
  • 👤 Arthur J. Coury

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 21:19
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/94; A61F2/945; A61F2/95; A61L; A61L31/00; A61L31/14; B; B29; B29C; B29C35/00; B29C35/02; B29C35/08; B29C55/00; B29C55/22; B29C55/24; B29C70/00; B29C70/68; B29C70/74; A61B; A61B17/00; A61B17/22; A61B2017/22001; A61F2210/00; A61F2210/0014; A61F2210/0023; A61F2210/0047; A61F2220/00; A61F2220/0008; A61F2250/00; A61F2250/0058; A61F2250/0096; A61F2250/0098; B29C35/0805; B29C2035/0822; B29C2035/0827; B29C2035/0833; B29K; B29K2995/00; B29K2995/0037; B29K2995/0059; B29K2995/006; B29L; B29L2023/00; B29L2031/00; B29L2031/753; B29L2031/7542; Y; Y10; Y10S; Y10S623/00; Y10S623/901

Claims Analysis

Total Claims: 25
Claim 1
Independent Claim 93 words
An article constructed and arranged for paving or stabilizing an irregularly contoured tissue surface of a lumen or hollow organ of a mammal, comprising: a polymeric structure having a surface that is softenable and thereby moldable in vivo, under conditions tolerable by a tissue surface, into intimate and conforming contact with the tissue surface; and a chromophore, added to the polymeric structure, selected to absorb a predetermined wavelength range of electromagnetic radiation thereby rendering the surface of the polymeric structure softenable and moldable in vivo under the conditions tolerable by the tissue surface.
Claim 2
Dependent Claim 93 words
An article constructed and arranged for paving or stabilizing an irregularly contoured tissue surface of a lumen or hollow organ of a mammal, comprising: a polymeric structure having a surface that is softenable and thereby moldable in vivo, under conditions tolerable by a tissue surface, into intimate and conforming contact with the tissue surface; and a chromophore, added to the polymeric structure, selected to absorb a predetermined wavelength range of electromagnetic radiation thereby rendering the surface of the polymeric structure softenable and moldable in vivo under the conditions tolerable by the tissue surface.
Claim 3
Dependent Claim 16 words
An article as in claim 1, wherein the polymeric structure is made of a biodegradable polymer.
Claim 4
Dependent Claim 14 words
An article as in claim 1, the article including at least one therapeutic agent.
Claim 5
Dependent Claim 12 words
An article as in claim 1, the article including a living cell.
Claim 6
Dependent Claim 13 words
An article as in claim 1, wherein the article has a multi-layered structure.
Claim 7
Dependent Claim 11 words
An article as in claim 1, further comprising a biocompatible coating.
Claim 8
Dependent Claim 47 words
An article as in claim 1, wherein the polymeric structure is made of a polymer selected from the group consisting of polymers of caprolactones, anhydrides, polylactides, glycolides, oxyalkylenes, carboxylic acids, urethanes, esters, amides, acrylonitriles, phosphazines, ethylene, vinyl fluoride, ethylene vinyl acetate, and blends and copolymeric combinations thereof.
Claim 9
Dependent Claim 40 words
An article as in claim 1, wherein the polymeric structure is made of a polymer selected from the group consisting of polymers of glycolic acid, glycolide, lactic acid, lactide, beta-hydroxybutyric acid, delta-valerolactone, p-dioxanone, epsilon-caprolactone, and blends and copolymeric combinations thereof.
Claim 10
Dependent Claim 20 words
An article as in claim 1, wherein the polymeric structure is made of a polymer of one or more anhydrides.
Claim 11
Dependent Claim 17 words
An article as in claim 9, wherein the polymeric structure includes subunits are at least partially crosslinked.
Claim 12
Dependent Claim 46 words
An article as in claim 1, wherein the surface that is moldable in vivo into intimate and conforming contact with the tissue surface is non-fluent at body temperature, becomes fluent at an altered temperature different from body temperature, and becomes non-fluent on returning to body temperature.
Claim 13
Dependent Claim 17 words
An article as in claim 11, wherein the altered temperature is a temperature higher than body temperature.
Claim 14
Dependent Claim 33 words
An article as in claim 1, wherein the polymeric structure is non-fluent at body temperature, becomes fluent at an altered temperature different from body temperature, and becomes non-fluent on returning to body temperature.
Claim 15
Dependent Claim 17 words
An article as in claim 13, wherein the altered temperature is a temperature higher than body temperature.
Claim 16
Dependent Claim 18 words
An article as in claim 1, constructed and adapted for application to the tissue surface with a catheter.
Claim 17
Dependent Claim 20 words
An article as in claim 15, adapted for application to the tissue surface with an expandable region of a catheter.
Claim 18
Dependent Claim 19 words
An article as in claim 15, wherein the article is on at least partially preformed stent, paving, or coating.
Claim 19
Dependent Claim 14 words
An article as in claim 17, wherein the article is a partially preformed stent.
Claim 20
Dependent Claim 13 words
An article as in claim 17, wherein the article is a cylindrical sleeve.
Claim 21
Dependent Claim 20 words
An article as in claim 1, constructed and arranged for paving or stabilizing an interior surface of a blood vessel.
Claim 22
Dependent Claim 19 words
An article as in claim 20, constructed and arranged for paving or stabilizing an interior surface of an artery.
Claim 23
Dependent Claim 24 words
An article as in claim 1, the article being partially preformed to approximately match the shape of the surface of the lumen or organ.
Claim 24
Dependent Claim 14 words
An article as in claim 1, wherein the chromophore comprises a dye or pigment.
Claim 25
Dependent Claim 25 words
An article as in claim 23, wherein the dye or pigment is selected from the group consisting of indocyanine eosin, copper, phthalocyanine, and combinations thereof.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-04-20 2001-10-20 2002-04-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-04-20 2005-10-20 2006-04-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-04-20 2009-10-20 2010-04-21 $7700.00 Window Closed / Lapsed

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