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US5558854A Expired / Lapsed US ⏱️ 0.0 years remaining

Ultrasound contrast media comprising perfluoropentane and perfluorohexane gas

Assignee: GE Healthcare Ltd
•
Filing: 1995-01-30
•
Granted: 1996-09-24
•
Expires: 2015-01-30
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Abstract

Abstract Ultrasound contrast media comprising gaseous perfluoropentane and gaseous perfluorohexane are disclosed.

Inventors

  • 👤 Steven C. Quay

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 03:35
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/22; A61K49/222; A61K49/223

Claims Analysis

Total Claims: 20
Claim 1
Independent Claim 8 words
Contrast media for ultrasound imaging comprising gaseous dodecafluoropentane.
Claim 2
Dependent Claim 8 words
Contrast media for ultrasound imaging comprising gaseous dodecafluoropentane.
Claim 3
Dependent Claim 20 words
The contrast media of claim 1 wherein a portion of said dodecafluoropentane is present as microbubbles suspended in a carrier.
Claim 4
Dependent Claim 13 words
The contrast media of claim 2 wherein said carrier is an aqueous liquid.
Claim 5
Dependent Claim 19 words
The contrast media of claim 3 wherein a portion of said microbubbles are less than 8 microns in diameter.
Claim 6
Dependent Claim 16 words
A biocompatible ultrasound contrast agent containing gas-filled liposomes, the improvement comprising including dodecafluoropentane in said gas.
Claim 7
Dependent Claim 16 words
A biocompatible ultrasound contrast agent containing gas-filled liposomes, the improvement comprising including dodecafluoropentane in said gas.
Claim 8
Dependent Claim 25 words
A biocompatible ultrasound contrast agent containing a suspension of encapsulated air-filled microspheres, the improvement comprising replacing all or a portion of the air with dodecafluoropentane.
Claim 9
Dependent Claim 25 words
A biocompatible ultrasound contrast agent containing a suspension of encapsulated air-filled microspheres, the improvement comprising replacing all or a portion of the air with dodecafluoropentane.
Claim 10
Dependent Claim 23 words
A biocompatible ultrasound contrast agent containing a suspension of crystals in a saccharide diluent, the improvement comprising providing gaseous dodecafluoropentane in said diluent.
Claim 11
Dependent Claim 23 words
A biocompatible ultrasound contrast agent containing a suspension of crystals in a saccharide diluent, the improvement comprising providing gaseous dodecafluoropentane in said diluent.
Claim 12
Dependent Claim 22 words
A biocompatible ultrasound contrast agent containing an emulsion of highly fluorinated organic compounds, the improvement comprising providing gaseous dodecafluoropentane in said emulsion.
Claim 13
Dependent Claim 22 words
A biocompatible ultrasound contrast agent containing an emulsion of highly fluorinated organic compounds, the improvement comprising providing gaseous dodecafluoropentane in said emulsion.
Claim 14
Dependent Claim 22 words
A biocompatible ultrasound contrast agent containing an air-filled microbubble suspension, the improvement comprising providing dodecafluoropentane gas within the microbubbles of said suspension.
Claim 15
Dependent Claim 22 words
A biocompatible ultrasound contrast agent containing an air-filled microbubble suspension, the improvement comprising providing dodecafluoropentane gas within the microbubbles of said suspension.
Claim 16
Dependent Claim 8 words
Contrast media for ultrasound imaging comprising gaseous perfluorohexane.
Claim 17
Dependent Claim 8 words
Contrast media for ultrasound imaging comprising gaseous perfluorohexane.
Claim 18
Dependent Claim 20 words
The contrast agent of claim 10 wherein a portion of said perfluorohexane is present as microbubbles suspended in a carrier.
Claim 19
Dependent Claim 13 words
The contrast agent of claim 11 wherein said carrier is an aqueous liquid.
Claim 20
Dependent Claim 19 words
The contrast agent of claim 11 wherein a portion of said microbubbles are less than 8 microns in diameter.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-09-24 2000-03-25 2000-09-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-09-24 2004-03-25 2004-09-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-09-24 2008-03-25 2008-09-24 $7700.00 Window Closed / Lapsed

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