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US5362494A
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Cosmetic, dermo-pharmaceutical or vesicle-containing composition including clycerol-derived compounds
Assignee: L'Oréal SA
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Filing: 1992-07-14
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Granted: 1994-11-08
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Expires: 2012-07-14
Abstract
Abstract <IMAGE> (I) <IMAGE> (II) Non-ionic amphiphilic, glycerol-derived compounds having formula (I), where R is a radical selected from the group consisting of C4-28 branched or linear alkenyl or alkyl radicals or mixtures thereof, or is a -CH2A grouping in which A is -OR', -SR, (II) where R' is a saturated or unsaturated hydrocarbonated radical and n represents an average statistical value n greater than 1 and equal to or less than 6; and, when R' is a -CH2A radical, n is also 2. These compounds are surface-active agents and some may form vesicles.
Inventors
- 👤 Alexandre Zysman
- 👤 Henri Sebag
- 👤 Alain Ribier
- 👤 Guy Vanlerberghe
- 👤 Claude Mahieu
- 👤 Claude Berthelot
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 16:26
CPC Classifications
C; C07; C07D; C07D317/00; C07D317/08; C07D317/10; C07D317/14; C07D317/18; C07D317/22; A; A61; A61K; A61K8/00; A61K8/02; A61K8/14; A61K8/18; A61K8/30; A61K8/33; A61K8/39; A61Q; A61Q19/00; C07C; C07C323/00; C07C323/10; C07C323/11; C07C323/12; C07C43/00; C07C43/02; C07C43/03; C07C43/04; C07C43/10; C07C43/11; C07C43/13; C07C43/135; C07C43/14; C07C43/178; C07C43/20; C07C43/23; C07C69/00; C07C69/02; C07C69/22; C07C69/33; A61Q1/00; A61Q1/02; A61Q1/04; A61Q1/06; A61Q17/00; A61Q17/04; A61Q19/002; A61Q19/04; A61Q19/08; Y; Y10; Y10S; Y10S516/00; Y10S516/01; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2984
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
99 words
A cosmetic or dermopharmaceutical composition comprising as a surfactant, at least one nonionic amphiphilic compound having formula (I): ##STR30## wherein R represents a radical selected from the group consisting of (i) a linear or branched C 4 -C 28 alkyl or alkenyl, or a mixture thereof, and (ii) --CH 2 A wherein A represents --OR', --SR' or ##STR31## wherein R' represents a saturated or unsaturated hydrocarbon, and n represents an average statistical value n greater than 1 and equal to not more than 6 and, when R represents --CH 2 A, n also represents a value equal to 2.
Claim 2
Dependent Claim
99 words
A cosmetic or dermopharmaceutical composition comprising as a surfactant, at least one nonionic amphiphilic compound having formula (I): ##STR30## wherein R represents a radical selected from the group consisting of (i) a linear or branched C 4 -C 28 alkyl or alkenyl, or a mixture thereof, and (ii) --CH 2 A wherein A represents --OR', --SR' or ##STR31## wherein R' represents a saturated or unsaturated hydrocarbon, and n represents an average statistical value n greater than 1 and equal to not more than 6 and, when R represents --CH 2 A, n also represents a value equal to 2.
Claim 3
Dependent Claim
75 words
The composition of claim 1 which also contains an ionic surfactant; a nonionic surfactant other than the compound of formula (I); a natural or synthetic, ionic or nonionic polymer; an oil; a wax; a hydrolyzed protein; a thickener; a pearlescent agent; an emollient; a hydrating agent; a colorant; a reducing agent; an oxidizing agent; a preservative; a perfume; an anti-UV screening agent; a solvent; a propellant; a pharmaceutically active product; or a parapharmaceutically active product.
Claim 4
Dependent Claim
23 words
The composition of claim 1 wherein said compound of formula (I) is present in an amount ranging from 0.5 to 50 weight percent.
Claim 5
Dependent Claim
23 words
The composition of claim 1 wherein said compound of formula (I) is present in an amount ranging from 0.5 to 25 weight percent.
Claim 6
Dependent Claim
23 words
The composition of claim 1 which also contains (i) a cosmetic active compound, (ii) a dermopharmaceutical active compound, or both (i) and (ii).
Claim 7
Dependent Claim
113 words
The composition of claim 5 wherein said cosmetic active compound or said dermopharmaceutical active compound is selected from the group consisting of an antioxidant or free-radical inhibitor; a hydrating or humectant agent; a tanning agent; a depigmenting agent; a skin coloration agent; a liporegulator; an anti-aging or anti-wrinkle agent; an anti-UV agent; a keratolytic agent; an emollient; an anti-inflammatory agent; a refreshing agent; a cicatrizing agent; a vasoprotective agent; an antibacterial agent; an antifungal agent; an insect repellant agent; an antiperspirant agent; a deodorant agent; an anti-dandruff agent; an agent for combatting hair loss; a hair dye; a hair bleaching agent; a reducing agent for permanent waving of hair; and a hair conditioner.
Claim 8
Dependent Claim
19 words
The composition of claim 1 which contains at least one formulation additive having neither cosmetic activity nor dermopharmaceutical activity.
Claim 9
Dependent Claim
30 words
The composition of claim 7 wherein said formulation additive is selected from the group consisting of a gelling agent, a polymer, a preservative, a colorant, an opacifier and a perfume.
Claim 10
Dependent Claim
94 words
A composition comprising a dispersion in an aqueous medium of vesicles bounded by one or more lamellae of a lipid phase containing at least one nonionic amphiphilic compound having formula (I): ##STR32## wherein R represents (i) a linear C 14 -C 18 alkyl radical or (ii) --CH 2 A wherein A represents OR' wherein R' a linear C 10 -C 18 alkyl radical, and n represents an average statistical value n greater than 1 and equal to not more than 3 and, when R represents --CH 2 A, n is also equal to 2.
Claim 11
Dependent Claim
94 words
A composition comprising a dispersion in an aqueous medium of vesicles bounded by one or more lamellae of a lipid phase containing at least one nonionic amphiphilic compound having formula (I): ##STR32## wherein R represents (i) a linear C 14 -C 18 alkyl radical or (ii) --CH 2 A wherein A represents OR' wherein R' a linear C 10 -C 18 alkyl radical, and n represents an average statistical value n greater than 1 and equal to not more than 3 and, when R represents --CH 2 A, n is also equal to 2.
Claim 12
Dependent Claim
33 words
The composition of claim 9 wherein said lipid phase also contains (i) an ionic lipid, (ii) a nonionic lipid other than the nonionic amphiphilic compound of formula (I) or both (i) and (ii).
Claim 13
Dependent Claim
36 words
The composition of claim 9 wherein said lipid phase also contains (i) an additive to decrease the permeability of said vesicles, (ii) an additive to improve the stability of said vesicles or both (i) and (ii).
Claim 14
Dependent Claim
78 words
The composition of claim 11 wherein said lipid phase contains a member selected from the group consisting of a sterol or oxyethylenated, acid sulfate, alkali metal sulfate, acid phosphate or alkali metal phosphate derivatives thereof; a long chain alcohol or diol; a long chain amine or quaternary ammonium derivative thereof; a dihydroxyalkylamine; a polyoxyethylenated fatty amine; a long chain amino alcohol ester or a salt or quaternary ammonium derivative thereof; and a phosphoric ester of a fatty alcohol.
Claim 15
Dependent Claim
36 words
The composition of claim 9 wherein said vesicles encapsulate an aqueous phase and wherein said lipid phase or said encapsulated aqueous phase or both, contains a cosmetic active compound or a dermopharmaceutical active compound, or both.
Claim 16
Dependent Claim
39 words
The composition of claim 9 wherein said aqueous medium in which said vesicles are dispersed contains at least one of (i) a water-soluble cosmetic compound, (ii) a dermopharmaceutical compound, (iii) an amphiphilic active compound or (iv) a mixture thereof.
Claim 17
Dependent Claim
32 words
The composition of claim 9 wherein the walls of said vesicles contain at least one of (i) a fat-soluble cosmetic active compound or (ii) a dermopharmaceutical compound or both (i) and (ii).
Claim 18
Dependent Claim
25 words
The composition of claim 9 wherein said aqueous medium in which said vesicles are dispersed also contains a dispersion of droplets of a water-immiscible liquid.
Claim 19
Dependent Claim
31 words
The composition of claim 16 wherein said water-immiscible liquid contains at least one of (i) a fat-soluble cosmetic active compound, (ii) a fat-soluble dermopharmaceutical active compound or both (i) and (ii).
Claim 20
Dependent Claim
47 words
The composition of claim 16 wherein said water-immiscible liquid is selected from the group consisting of an animal oil, a vegetable oil, a natural or synthetic essential oil, a halogenated hydrocarbon, a silicone, an ester of an inorganic acid and an alcohol, an ether and a polyether.
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-11-07 | 1998-05-09 | 1998-11-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-11-07 | 2002-05-09 | 2002-11-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-11-07 | 2006-05-09 | 2006-11-08 | $7700.00 | Window Closed / Lapsed |