US4954345A
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Dermally acting pharmaceutical preparation with liposomes as vehicle means
Assignee: Roehm Pharma GmbH
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Filing: 1988-08-15
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Granted: 1990-09-04
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Expires: 2008-08-15
Abstract
Abstract The present invention is directed to a pharmaceutical preparation for external or transdermal application which comprises a dispersion of liposomes, wherein said liposomes incorporate or enclose an active ingredient.
Inventors
- 👤 Joseph Muller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 16:44
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/10; A61K9/127; A61K8/00; A61K8/02; A61K8/14; A61K8/18; A61K8/30; A61K8/33; A61K8/34; A61K8/347; A61Q; A61Q19/00; Y; Y10; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2984
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
58 words
A dermally acting pharmaceutical preparation for external application to the skin, consisting essentially of: a dispersion, wherein said dispersion comprises urea and at least one active ingredient selected from the group consisting of corticosteroids and trihydroxyanthracenes and is in dissolved, emulsified or suspended form, and wherein said urea and said active ingredient are incorporated or enclosed in liposomes.
Claim 2
Dependent Claim
58 words
A dermally acting pharmaceutical preparation for external application to the skin, consisting essentially of: a dispersion, wherein said dispersion comprises urea and at least one active ingredient selected from the group consisting of corticosteroids and trihydroxyanthracenes and is in dissolved, emulsified or suspended form, and wherein said urea and said active ingredient are incorporated or enclosed in liposomes.
Claim 3
Dependent Claim
17 words
The preparation of claim 1, wherein said active ingredient is useful for the treatment of skin disorders.
Claim 4
Dependent Claim
12 words
The preparation of claim 1, wherein said active ingredient is a corticosteroid.
Claim 5
Dependent Claim
23 words
The preparation of claim 3, wherein said corticosteroid is a member selected from the group consisting of fluorocortisone, fluorocortolone, fluoroandrenolone, triamcinolone and methylprednisolone.
Claim 6
Dependent Claim
10 words
The preparation of claim 4, wherein said corticosteroid is triamcinolone.
Claim 7
Dependent Claim
12 words
The preparation of claim 1, wherein said active ingredient is a trihydroxyanthracene.
Claim 8
Dependent Claim
12 words
The preparation of claim 6, wherein said trihydroxyanthracene is 1,2,10-trihydroxyanthracene or dithranol.
Claim 9
Dependent Claim
10 words
The preparation of claim 7, wherein said trihydroxyanthracene is dithranol.
Claim 10
Dependent Claim
15 words
The preparation of claim 1, wherein said liposomes contain one or more corticosteroids and dithranol.
Claim 11
Dependent Claim
15 words
The preparation of claim 1, wherein said active ingredient is useful for treating non-skin disorders.
Claim 12
Dependent Claim
26 words
The preparation of claim 1, further comprising additional ingredients selected from the group consisting of sterols, dialkyl phosphates, sphingomyelin, antioxidants, sugar derivatives and amino sugar derivatives.
Claim 13
Dependent Claim
16 words
A method of treating skin disorders, comprising contacting skin with the pharmaceutical preparation of claim 1.
Claim 14
Dependent Claim
16 words
A method of treating non-skin disorders comprising transdermal administration of the pharmaceutical preparation of claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-09-03 | 1994-03-05 | 1994-09-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-09-03 | 1998-03-05 | 1998-09-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-09-03 | 2002-03-05 | 2002-09-04 | $7700.00 | Window Closed / Lapsed |