Patent US5322925A successfully refreshed from Google Patents.
US5322925A
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US
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Absorbable block copolymers and surgical articles made therefrom
Assignee: United States Surgical Corp
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Filing: 1993-03-19
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Granted: 1994-06-21
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Expires: 2013-03-19
Abstract
Abstract Block copolymers have a first copolymer block wherein lactide is the predominant component and a second copolymer block wherein trimethylene carbonate is the predominant component. The copolymers are useful in forming surgical devices, including monofilament sutures.
Inventors
- 👤 Ross R. Muth
- 👤 Nagabhushanam Totakura
- 👤 Cheng-Kung Liu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:13
CPC Classifications
C; C08; C08G; C08G63/00; C08G63/64; A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2031; A61K9/204; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/26; A61L17/00; A61L17/06; A61L17/10; A61L17/12; A61L31/00; A61L31/04; A61L31/06
Claims Analysis
Total Claims: 28
Claim 1
Independent Claim
69 words
A block copolymer comprising: a) a first block formed from a copolymer having lactide as the predominant component therefore copolymerized with one or more comonomers selected from the group consisting of glycolide, p-dioxanone and ε-caprolactone; and b) a second block formed from a copolymer having trimethylene carbonate as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, lactide, p-dioxanone and ε-caprolactone.
Claim 2
Dependent Claim
69 words
A block copolymer comprising: a) a first block formed from a copolymer having lactide as the predominant component therefore copolymerized with one or more comonomers selected from the group consisting of glycolide, p-dioxanone and ε-caprolactone; and b) a second block formed from a copolymer having trimethylene carbonate as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, lactide, p-dioxanone and ε-caprolactone.
Claim 3
Dependent Claim
21 words
A copolymer as in claim 1 wherein said first block comprises lactide in an amount greater than about 70 mole percent.
Claim 4
Dependent Claim
16 words
A copolymer as in claim 1 wherein said first block comprises about 80 mole percent lactide.
Claim 5
Dependent Claim
22 words
A copolymer as in claim 1 wherein said second block comprises trimethylene carbonate in an amount greater than about 70 mole percent.
Claim 6
Dependent Claim
16 words
A copolymer as in claim 1 wherein said second block comprises about 80 percent trimethylene carbonate.
Claim 7
Dependent Claim
24 words
A copolymer as in claim 1 wherein said first block comprises from about 10 to about 90 percent by weight of the block copolymer.
Claim 8
Dependent Claim
23 words
A copolymer as in claim 1 wherein said second block comprises from about 10 to about 90 percent by weight of the coplymer.
Claim 9
Dependent Claim
34 words
A copolymer as in claim 1 wherein said first block comprises about 70 percent by weight of the block copolymer and said second block comprises about 30 percent by weight of the block copolymer.
Claim 10
Dependent Claim
61 words
A copolymer as in claim 1 wherein said first block comprises about 75% by weight of the block copolymer and contains about 80 percent lactide, the remainder of said first block being glycolide, and said second block comprises about 25% by weight of the block copolymer, and contains about 70 percent trimethylene carbonate, the remainder of said second block being lactide.
Claim 11
Dependent Claim
75 words
A surgical article comprising one or more fibers made from a block copolymer having a first block comprising a copolymer having lactide as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, p-dioxonane and ε-caprolactone and a second block comprising a copolymer having trimethylene carbonate as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, lactide, p-dioxanone and ε-caprolactone.
Claim 12
Dependent Claim
75 words
A surgical article comprising one or more fibers made from a block copolymer having a first block comprising a copolymer having lactide as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, p-dioxonane and ε-caprolactone and a second block comprising a copolymer having trimethylene carbonate as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, lactide, p-dioxanone and ε-caprolactone.
Claim 13
Dependent Claim
22 words
A surgical article as in claim 10 wherein said first block comprises lactide in an amount greater than about 70 mole percent.
Claim 14
Dependent Claim
17 words
A surgical article as in claim 10 wherein said first block comprises about 80 mole percent lactide.
Claim 15
Dependent Claim
23 words
A surgical article as in claim 10 wherein said second block comprises trimethylene carbonate in an amount greater than about 70 mole percent.
Claim 16
Dependent Claim
17 words
A surgical article as in claim 10 wherein said second block comprises about 80 percent trimethylene carbonate.
Claim 17
Dependent Claim
25 words
A surgical article as in claim 10 wherein said first block comprises from about 10 to about 90 percent by weight of the block copolymer.
Claim 18
Dependent Claim
24 words
A surgical article as in claim 10 wherein said second block comprises from about 10 to about 90 percent by weight of the copolymer.
Claim 19
Dependent Claim
35 words
A surgical article as in claim 10 wherein said first block comprises about 70 percent by weight of the block copolymer and said second block comprises about 30 percent by weight of the block copolymer.
Claim 20
Dependent Claim
62 words
A surgical article as in claim 10 wherein said first block comprises about 75% by weight of the block copolymer and contains about 80 percent lactide, the remainder of said first block being glycolide, and said second block comprises about 25% by weight of the block copolymer and contains about 70 percent trimethylene carbonate, the remainder of said second block being lactide.
Claim 21
Dependent Claim
14 words
A surgical article as in claim 10 wherein said surgical element is a suture.
Claim 22
Dependent Claim
33 words
A surgical article as in claim 10 wherein said surgical article is selected from the group consisting of staples, clips and other fasteners, would dressings, drug delivery devices, pins, screws and other implants.
Claim 23
Dependent Claim
15 words
A surgical article as in claim 20 wherein said surgical article is a bone pin.
Claim 24
Dependent Claim
72 words
An absorbable surgical suture comprising a block copolymer having a first block formed from a copolymer having lactide as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, p-dioxonane and ε-caprolactone and a second block formed from a copolymer having trimethylene carbonate as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, lactide, p-dioxanone and ε-caprolactone.
Claim 25
Dependent Claim
72 words
An absorbable surgical suture comprising a block copolymer having a first block formed from a copolymer having lactide as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, p-dioxonane and ε-caprolactone and a second block formed from a copolymer having trimethylene carbonate as the predominant component thereof copolymerized with one or more comonomers selected from the group consisting of glycolide, lactide, p-dioxanone and ε-caprolactone.
Claim 26
Dependent Claim
24 words
An absorbable suture as in claim 22 wherein said suture retains at least about 30 percent of its in vitro strength after 6 weeks.
Claim 27
Dependent Claim
62 words
An absorbable suture as in claim 22 wherein said first block comprises about 75% by weight of the block copolymer and contains about 80 percent lactide, the remainder of said first block being glycolide, and said second block comprises about 25% by weight of the block copolymer and contains about 70 percent trimethylene carbonate, the remainder of said second block being lactide.
Claim 28
Dependent Claim
22 words
A method of closing a wound comprising suturing with a suture made at least in part from the copolymer of claim 1.
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1997-06-20 | 1997-12-20 | 1998-06-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-06-20 | 2001-12-20 | 2002-06-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-06-20 | 2005-12-20 | 2006-06-21 | $7700.00 | Window Closed / Lapsed |