Patent US5256764A successfully refreshed from Google Patents.
US5256764A
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Medical devices fabricated from homopolymers and copolymers having recurring carbonate units
Assignee: United States Surgical Corp
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Filing: 1992-07-22
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Granted: 1993-10-26
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Expires: 2012-07-22
Abstract
Abstract This invention relates to medical devices formed totally or in part from homopolymers or copolymers comprising recurring carbonate moieties.
Inventors
- 👤 Reginald T. Tang
- 👤 Frank Mares
- 👤 William J. Boyle, Jr.
- 👤 Tin-Ho Chiu
- 👤 Kundanbhai M. Patel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:16
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/14; A61L27/18; A61L15/00; A61L15/16; A61L15/42; A61L15/64; A61L17/00; A61L17/06; A61L17/10; A61L31/00; A61L31/04; A61L31/06; Y; Y10; Y10T; Y10T442/00; Y10T442/30; Y10T442/3065; Y10T442/3089; Y10T442/3098; Y10T442/3106; Y10T442/3114; Y10T442/3122; Y10T442/3976; Y10T442/40; Y10T442/425; Y10T442/431; Y10T442/50; Y10T442/60; Y10T442/608; Y10T442/609; Y10T442/61; Y10T442/611; Y10T442/612; Y10T442/696
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
255 words
A medical device comprising a body, said body formed totally or in part of one or more biopolymers selected from the group consisting of homopolymers having recurring monomeric unit selected from the group consisting of General Structures I or II: ##STR12## wherein: --Z-- is --C(R 5 R 6 )--, --O-- or a combination thereof; where Z is selected such that there are no adjacent heteroatoms; n is from 1 to about 8; m is from 1 to about 8; R 1 , R 2 , R 3 , and R 4 are the same or different at each occurrence and are hydrogen, aryloxyalkyl, alkyoxyaryl, aryloxyaryl, arylalkyl, alkylarylalkyl, arylalkylaryl, alkylaryl, arylcarbonylalkyl, alkyl, aryl, alkylcarbonylalkyl, cycloalkyl, arylcarbonylaryl, alkylcarbonylaryl, alkoxyalkyl, or aryl or alkyl substituted with one or more substituents selected from the group consisting of alkyl, aryl, alkoxy, aryloxy, dialkylamino, diarylamino and alkylarylamino; and R 5 and R 6 are the same or different and are R 1 , R 2 , R 3 , R 4 , dialkylamino, diarylamino, alkylarylamino, alkoxy, aryloxy, alkanoyl, or arylcarbonyl, or any two of R1 to R5 together may form an alkylene chain completing a 3, 4, 5, 6, 7, 8 or 9 membered alicyclic fused, spiro, bicyclic or tricyclic ring system or a combination thereof, which system may optionally include one or more non-adjacent carbonyl, oxa, alkylaza or arylaza groups; with the proviso that when the said biopolymers are homopolymers having recurring units of the Structure II derived from ethylene carbonate or propylene carbonate then m is other than 1.
Claim 2
Dependent Claim
255 words
A medical device comprising a body, said body formed totally or in part of one or more biopolymers selected from the group consisting of homopolymers having recurring monomeric unit selected from the group consisting of General Structures I or II: ##STR12## wherein: --Z-- is --C(R 5 R 6 )--, --O-- or a combination thereof; where Z is selected such that there are no adjacent heteroatoms; n is from 1 to about 8; m is from 1 to about 8; R 1 , R 2 , R 3 , and R 4 are the same or different at each occurrence and are hydrogen, aryloxyalkyl, alkyoxyaryl, aryloxyaryl, arylalkyl, alkylarylalkyl, arylalkylaryl, alkylaryl, arylcarbonylalkyl, alkyl, aryl, alkylcarbonylalkyl, cycloalkyl, arylcarbonylaryl, alkylcarbonylaryl, alkoxyalkyl, or aryl or alkyl substituted with one or more substituents selected from the group consisting of alkyl, aryl, alkoxy, aryloxy, dialkylamino, diarylamino and alkylarylamino; and R 5 and R 6 are the same or different and are R 1 , R 2 , R 3 , R 4 , dialkylamino, diarylamino, alkylarylamino, alkoxy, aryloxy, alkanoyl, or arylcarbonyl, or any two of R1 to R5 together may form an alkylene chain completing a 3, 4, 5, 6, 7, 8 or 9 membered alicyclic fused, spiro, bicyclic or tricyclic ring system or a combination thereof, which system may optionally include one or more non-adjacent carbonyl, oxa, alkylaza or arylaza groups; with the proviso that when the said biopolymers are homopolymers having recurring units of the Structure II derived from ethylene carbonate or propylene carbonate then m is other than 1.
Claim 3
Dependent Claim
62 words
The device of claim 1 wherein R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are the same or different and are selected from the group consisting of hydrogen, alkyl, cycloalkyl, alkylaryl, alkoxyalkyl, aryloxyalkyl, aryloxyaryl, aryl and arylalkyl groups, and aryl, arylalkyl or alkylaryl substituted with one or more alkyl, alkoxy and alkoxyalkyl groups.
Claim 4
Dependent Claim
57 words
The device of claim 2 wherein R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are the same of different and are selected from the groups consisting of hydrogen, alkyl, cycloalkyl, alkylphenyl, alkoxyalkyl and phenylalkyl, and phenyl, alkylphenyl and phenylalkyl substituted with one or more alkyl or alkoxy groups.
Claim 5
Dependent Claim
68 words
The device of claim 3 wherein: Z is --C(R 5 R 6 )--, --O-- or a combination thereof; n is 1, 2, or 3; m is 1, 2, 3, 4, 5 or 6; and R 1 to R 6 are selected from the group consisting of substitutents in which aliphatic moieties include up to about 10 carbon atoms and aryl moieties include up to about 16 carbon atoms.
Claim 6
Dependent Claim
94 words
The device of claim 1 wherein said biopolymers comprises recurring monomeric units of the following general Structures II or III: ##STR13## wherein: n is 1 to about 3; m is 1 to about 4; R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are the same or different and are hydrogen, aryl, alkylaryl, arylalkyl or alkyl, or R 5 and R 6 together may form an aliphatic chain having from about 3 to about 10 membered spiro, bicyclic, or tricyclic ring structure or a combination thereof.
Claim 7
Dependent Claim
48 words
The device of claim 5 wherein: n is 1, 2 or 3; m is 1, 2 or 3; and R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are the same or different and are hydrogen, alkyl, phenylalkyl or alkylphenyl.
Claim 8
Dependent Claim
41 words
The device of claim 6 wherein R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are the same or different and are hydrogen or alkyl having from 1 to about 7 carbon atoms.
Claim 9
Dependent Claim
127 words
The device of claim 1 wherein the biopolymers comprises recurring monomeric units selected from the group consisting of: ##STR14## wherein: R 5 and R 6 are the same or different and are hydrogen, alkyl, aryl, cycloalkyl, arylalkyl, alkoxyalkyl, aryloxyalkyl, or aryl or arylalkyl substituted with one or more alkyl or alkoxy groups, alkanoyl, dialkylamino, or R 5 or R 6 together may form an alkylene chain completing a 4, 5, 6, 7, 8, 9 or 10 membered spiro, bicyclic, or tricyclic ring structure or a combination thereof, which structure may optionally include one or more nonadjacent divalent carbonyl, oxa, alkylaza or arylaza groups with the proviso that at least one or R 5 or R 6 is other than hydrogen; and n is 1, 2 or 3.
Claim 10
Dependent Claim
42 words
The device of claim 8 wherein R 5 and R 6 are the same or different and are phenyl, phenylalkyl, alkylphenyl, alkyl, or R 5 and R 6 together form alkylene a divalent chain forming a 4 to 8 membered ring structure.
Claim 11
Dependent Claim
27 words
The device of claim 9 wherein R 5 and R 6 together form a 5 to 7 membered spiro or bicyclic ring structure or a combination thereof.
Claim 12
Dependent Claim
14 words
The device of claim 8 wherein R 5 and R 6 are the same.
Claim 13
Dependent Claim
23 words
The device of claim 11 wherein R 5 and R 6 are the same or different and are alkyl, phenyl, alkylphenyl or phenylalkyl.
Claim 14
Dependent Claim
13 words
The device of claim 8 wherein R 5 and R 6 are hydrogen.
Claim 15
Dependent Claim
27 words
The device of claim 12 wherein R 5 and R 6 are the same or different and are alkyl of from about 1 to 7 carbon atoms.
Claim 16
Dependent Claim
20 words
The device of claim 13 wherein R 5 and R 6 are alkyl of about 1 to 4 carbon atoms.
Claim 17
Dependent Claim
26 words
The device of claim 1 which is a bioresorbable medical device suitable for implantation in side of a living system to promote regeneration of body tissue.
Claim 18
Dependent Claim
10 words
The device of claim 1 which is a nerve channel.
Claim 19
Dependent Claim
15 words
The device of claim 1 which is a vascular device for vascular regeneration or growth.
Claim 20
Dependent Claim
16 words
The device of claim 1 which is an orthopedica device for bone repair or fracture fixation.
Claim 21
Dependent Claim
14 words
The device of claim 1 which is a wound covering or wound closure device.
Claim 22
Dependent Claim
12 words
The device of claim 1 for tendon or ligament regeneration or repair.
Claim 23
Dependent Claim
31 words
A device of claim 1 which comprises a portion formed of said biopolymer and a portion formed a biodurable material, a bioresorbable polymer other than said biopolymer or a combination thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-10-25 | 1997-04-26 | 1997-10-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-10-25 | 2001-04-26 | 2001-10-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-10-25 | 2005-04-26 | 2005-10-26 | $7700.00 | Window Closed / Lapsed |