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Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom

Assignee: Collagenesis Inc
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Filing: 1992-01-22
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Granted: 1993-04-13
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Expires: 2012-01-22
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Abstract

Abstract The present invention provides a biologically compatible collagenous reaction product comprising ethylenically unsaturated or polymeric substituted collagen, the monomeric substituents being essentially free of nitrogen, e.g., methacrylate, styrene, polyvinyl, ethylene. The collagenous reaction product can be polymerized, e.g., by exposure to UV irradiation, chemical agents or atmospheric oxygen, and molded to form useful medical implant articles. Methods of preparation are also provided.

Inventors

  • 👤 Charles D. Kelman
  • 👤 Dale P. DeVore

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 17:26
CPC Classifications
C; C08; C08F; C08F289/00; A; A61; A61L; A61L27/00; A61L27/14; A61L27/22; A61L27/24; G; G02; G02B; G02B1/00; G02B1/04; G02B1/041; G02B1/043; A61F; A61F2310/00; A61F2310/00005; A61F2310/00365; A61L2430/00; A61L2430/16; Y; Y10; Y10S; Y10S128/00; Y10S128/08; Y10S623/00; Y10S623/901

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 60 words
A shaped article useful for medical implantation comprising a biocompatible collagenous polymer of collagen modified with an acylating agent selected from the group consisting of glutaric anhydride, succinic anhydride, and maleic anhydride and at least one other acylating agent selected from the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene-maleic anhydride copolymer, styrene-maleic anhydride copolymer and poly(vinyl) sulfonic acid.
Claim 2
Dependent Claim 60 words
A shaped article useful for medical implantation comprising a biocompatible collagenous polymer of collagen modified with an acylating agent selected from the group consisting of glutaric anhydride, succinic anhydride, and maleic anhydride and at least one other acylating agent selected from the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene-maleic anhydride copolymer, styrene-maleic anhydride copolymer and poly(vinyl) sulfonic acid.
Claim 3
Dependent Claim 12 words
The shaped article of claim 1 wherein said product forms a lens.
Claim 4
Dependent Claim 25 words
The shaped article of claim 2 wherein said lens is selected from the group consisting of contact lens, corneal onlay, corneal inlay and intraocular lens.
Claim 5
Dependent Claim 43 words
The shaped article according to claim 1, comprising a biocompatible collagenous polymer of collagen modified with glutaric anhydride and at least one member of the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene-maleic anhydride copolymer, styrene-maleic anhydride copolymer, and poly(vinyl) sulfonic acid.
Claim 6
Dependent Claim 12 words
The shaped article of claim 4 wherein said product forms a lens.
Claim 7
Dependent Claim 25 words
The shaped article of claim 5, wherein said lens is selected from the group consisting of contact lens, corneal onlay, corneal inlay and intraocular lens.
Claim 8
Dependent Claim 40 words
A shaped article useful for medical implantation comprising a biocompatible collagenous polymer of collagen modified with an acrylating agent selected from the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene-maleic anhydride copolymer, styrene-maleic anhydride copolymer, and poly(vinyl) sulfonic acid.
Claim 9
Dependent Claim 40 words
A shaped article useful for medical implantation comprising a biocompatible collagenous polymer of collagen modified with an acrylating agent selected from the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene-maleic anhydride copolymer, styrene-maleic anhydride copolymer, and poly(vinyl) sulfonic acid.
Claim 10
Dependent Claim 12 words
The shaped article of claim 7, wherein said product forms a lens.
Claim 11
Dependent Claim 25 words
The shaped article of claim 8, wherein said lens is selected from the group consisting of contact lens, corneal onlay, corneal inlay and intraocular lens.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-04-12 1996-10-12 1997-04-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-04-12 2000-10-12 2001-04-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-04-12 2004-10-12 2005-04-13 $7700.00 Window Closed / Lapsed

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