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US5133934A Expired / Lapsed US ⏱️ 0.0 years remaining

Ionosphere and reporter substance incorporated into a hydrophobic carrier

Assignee: Bayer Corp
•
Filing: 1991-02-22
•
Granted: 1992-07-28
•
Expires: 2011-02-22
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Abstract

Abstract Compositions and test articles comprisng ionophore of an optically active isomer of bis(12-crown-4-methyl)dialkyl malonate, wherein alkyl group is methyl and the second alkyl group has 4 to 20 carbon atoms, with a reporter substance incorporated in a hydrophobic carrier are disclosed.

Inventors

  • 👤 James B. Denton
  • 👤 Kin-Fai Yip

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 22:12
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/84; C; C07; C07D; C07D323/00; G01N33/52; G01N33/521

Claims Analysis

Total Claims: 18
Claim 1
Independent Claim 72 words
A composition comprising: an optically active ionophore capable of forming an ionophore-ion complex comprising: an optically active isomer of bis (12-crown-4 methyl) dialkyl malonate, wherein one alkyl group is methyl and the second alkyl group has 4 to 20 carbon atoms; a suitable hydrophobic carrier; and a reporter substance capable of interacting with said ionophore-ion complex to produce a detectable response, said ionophore and said reporter substance being incorporated into said carrier.
Claim 2
Dependent Claim 72 words
A composition comprising: an optically active ionophore capable of forming an ionophore-ion complex comprising: an optically active isomer of bis (12-crown-4 methyl) dialkyl malonate, wherein one alkyl group is methyl and the second alkyl group has 4 to 20 carbon atoms; a suitable hydrophobic carrier; and a reporter substance capable of interacting with said ionophore-ion complex to produce a detectable response, said ionophore and said reporter substance being incorporated into said carrier.
Claim 3
Dependent Claim 19 words
The composition of claim 1 wherein said ionophore comprises an optically active isomer of bis (12-crown-4 methyl) dodecylmethyl malonate.
Claim 4
Dependent Claim 65 words
A composition comprising: an optically active ionophore capable of forming an ionophore-ion complex selected from the group consisting of (R),(R)-(+) bis (12-crown-4 methyl) dodecylmethyl malonate, (S),(S)-(-) bis (12-crown-4 methyl) dodecylmethyl malonate and mixtures thereof; a suitable hydrophobic carrier; and a reporter substance capable of interacting with said ionophore-ion complex to produce a detectable response, said ionophore and said reporter substance being incorporated into said carrier.
Claim 5
Dependent Claim 65 words
A composition comprising: an optically active ionophore capable of forming an ionophore-ion complex selected from the group consisting of (R),(R)-(+) bis (12-crown-4 methyl) dodecylmethyl malonate, (S),(S)-(-) bis (12-crown-4 methyl) dodecylmethyl malonate and mixtures thereof; a suitable hydrophobic carrier; and a reporter substance capable of interacting with said ionophore-ion complex to produce a detectable response, said ionophore and said reporter substance being incorporated into said carrier.
Claim 6
Dependent Claim 13 words
The composition of claim 3 wherein said carrier is an organic polymeric solid.
Claim 7
Dependent Claim 11 words
The composition of claim 4 wherein said reporter substance is 7-(n-decyl)-2-methyl-4-(3',5'-dichlorophen-4'-one)-indonaphthol.
Claim 8
Dependent Claim 56 words
A composition comprising: an optically active ionophore capable of forming an ionophore-ion complex, selected from the group consisting of (R),(R)-(+) bis (12-crown-4 methyl) dodecylmethyl malonate, (S), (S)-(-) bis (12-crown-4 methyl) dodecylmethyl malonate and mixtures thereof; a suitable hydrophobic carrier; and a reporter substance comprising 7-(n-decyl)-2-methyl-4-(3',5'-dichlorophen-4'-one)indonaphthol, said ionophore and said reporter substance being incorporated into said carrier.
Claim 9
Dependent Claim 56 words
A composition comprising: an optically active ionophore capable of forming an ionophore-ion complex, selected from the group consisting of (R),(R)-(+) bis (12-crown-4 methyl) dodecylmethyl malonate, (S), (S)-(-) bis (12-crown-4 methyl) dodecylmethyl malonate and mixtures thereof; a suitable hydrophobic carrier; and a reporter substance comprising 7-(n-decyl)-2-methyl-4-(3',5'-dichlorophen-4'-one)indonaphthol, said ionophore and said reporter substance being incorporated into said carrier.
Claim 10
Dependent Claim 75 words
A test article comprising a suitable support carrying a test system comprising: a suitable hydrophobic carrier having incorporated therein an optically active ionophore capable of forming an ionophore-ion complex comprising an optically active isomer of bis (12-crown-4 methyl) dialkyl malonate, wherein one alkyl group is methyl and the second alkyl group has about 4 to about 20 carbon atoms, and a reporter substance capable of interacting with said ionophore-ion complex to produce a detectable response.
Claim 11
Dependent Claim 75 words
A test article comprising a suitable support carrying a test system comprising: a suitable hydrophobic carrier having incorporated therein an optically active ionophore capable of forming an ionophore-ion complex comprising an optically active isomer of bis (12-crown-4 methyl) dialkyl malonate, wherein one alkyl group is methyl and the second alkyl group has about 4 to about 20 carbon atoms, and a reporter substance capable of interacting with said ionophore-ion complex to produce a detectable response.
Claim 12
Dependent Claim 11 words
The test article of claim 7 wherein said support is paper.
Claim 13
Dependent Claim 31 words
The test article of claim 8 wherein said ionophore is selected from the group consisting of (R),(R)-(+) bis (12-crown-4 methyl) dialkyl malonate, (S),(S)-(-) bis (12-crown-4 methyl) dialkyl malonate and mixtures thereof.
Claim 14
Dependent Claim 31 words
The test article of claim 9 wherein said ionophore is selected from the group consisting of (R),(R)-(+) bis (12-crown-4 methyl) dodecylmethyl malonate, (S),(S)-(-) bis (12-crown-4 methyl) dodecylmethyl malonate and mixtures thereof.
Claim 15
Dependent Claim 12 words
The test article of claim 10 wherein said reporter compound is 7-(n-decyl)-2-methyl-4-(3',5'-dichlorophen-4'-one)-indonaphthol.
Claim 16
Dependent Claim 66 words
A test article comprising a suitable support carrying a test system comprising a suitable hydrophobic carrier having incorporated therein an optically active ionophore capable of forming an ionophore-ion complex selected from the group consisting of (R),(R)-(+) bis (12-crown-4 methyl) dodecylmethyl malonate, (S),(S)-(-) bis (12-crown-4 methyl) dodecylmethyl malonate and mixtures thereof, and a reporter substance capable of interacting with said ionophore-ion complex to produce a detectable response.
Claim 17
Dependent Claim 66 words
A test article comprising a suitable support carrying a test system comprising a suitable hydrophobic carrier having incorporated therein an optically active ionophore capable of forming an ionophore-ion complex selected from the group consisting of (R),(R)-(+) bis (12-crown-4 methyl) dodecylmethyl malonate, (S),(S)-(-) bis (12-crown-4 methyl) dodecylmethyl malonate and mixtures thereof, and a reporter substance capable of interacting with said ionophore-ion complex to produce a detectable response.
Claim 18
Dependent Claim 12 words
The test articles of claim 12 wherein said reporter substance is 7-(n-decyl)-2-methyl-4-(3',5'-dichlorophen-4'-one)-indonaphthol.

References Cited (Backward Citations)

US4734375A Cited
US4523994A Cited
US4645744A Cited
US4649123A Cited
US4504368A Cited
US4670218A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-07-28 1996-01-27 1996-07-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-07-28 2000-01-27 2000-07-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-07-28 2004-01-27 2004-07-28 $7700.00 Window Closed / Lapsed

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