US5015373A
Expired / Lapsed
US
⏱️ 0.0 years remaining
High stability porous zirconium oxide spherules
Assignee: University of Minnesota System
•
Filing: 1989-10-11
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Granted: 1991-05-14
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Expires: 2009-10-11
Abstract
Abstract The present invention provides a stable stationary phase for chromatography which comprises porous ZrO2 spherules coated with a cross-linked polymer coating wherein said coated spherules have a pore size from about 20-500 ANGSTROM and a particle diameter range of about 0.5-500 microns, and are stable in basic media to pHs of up to about 14.
Inventors
- 👤 Peter W. Carr
- 👤 Eric F. Funkenbusch
- 👤 Martin P. Rigney
- 👤 Patrick L. Coleman
- 👤 Douglas A. Hanggi
- 👤 Wes A. Schafer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 07:43
CPC Classifications
B; B01; B01J; B01J20/00; B01J20/281; B01J20/286; B01J20/287; B01J20/02; B01J20/06; B01J20/30; B01J20/32; B01J20/3202; B01J20/3204; B01J20/3231; B01J20/3242; B01J20/3268; B01J20/328; B01J20/3282; B01J39/00; B01J39/08; B01J39/12; B82; B82Y; B82Y30/00; C; C01; C01G; C01G25/00; C01G25/02; B01J2220/00; B01J2220/50; B01J2220/54; C01P; C01P2004/00; C01P2004/30; C01P2004/32; C01P2004/60; C01P2004/61; C01P2004/62; C01P2004/64; C01P2004/80; C01P2006/00; C01P2006/12; C01P2006/14; C01P2006/16; C01P2006/17; G; G01; G01N; G01N30/00; G01N30/02; G01N30/50; G01N30/52; G01N2030/524; G01N2030/525
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
42 words
Porous ZrO 2 spherules coated with a hydrophobic cross-linked polymer coating wherein said coated spherules have a pore size from about 20-500 Å and a particle diameter range of about 0.5-500 microns, and are stable to about pH 14 in aqueous media.
Claim 2
Dependent Claim
42 words
Porous ZrO 2 spherules coated with a hydrophobic cross-linked polymer coating wherein said coated spherules have a pore size from about 20-500 Å and a particle diameter range of about 0.5-500 microns, and are stable to about pH 14 in aqueous media.
Claim 3
Dependent Claim
14 words
The coated ZrO 2 spherules of claim 1 wherein the polymer coating comprises polybutadiene.
Claim 4
Dependent Claim
31 words
The coated ZrO 2 spherules of claim 1 wherein the surface of the coated spherules is further modified by treatment with inorganic phosphate to impart a cation-exchange property to said spherules.
Claim 5
Dependent Claim
18 words
The coated ZrO 2 spherules of claim 3 wherein the inorganic phosphate is H 3 PO 4 .
Claim 6
Dependent Claim
39 words
The coated ZrO 2 sherules of claim 1 wherein the surface of the porous ZrO 2 spherules is deactivated by treatment with an effective amount of an organophosphonate or organophosphonic acid prior to application of the hydrophobic polymer coating.
Claim 7
Dependent Claim
15 words
The coated ZrO 2 spherules of claim 5 wherein the organophosphonic acid is allylphosphonic acid.
Claim 8
Dependent Claim
38 words
The coated ZrO 2 spherules of claim 1 wherein the surface of the coated ZrO 2 spherules is deactivated by treatment with an effective amount of an organophosphonate or organophosphonic acid following application of the hydrophobic polymer coating.
Claim 9
Dependent Claim
15 words
The coated ZrO 2 spherules of claim 7 wherein the organophosphonic acid is allyphosphonic acid.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-05-13 | 1994-11-12 | 1995-05-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-05-13 | 1998-11-12 | 1999-05-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-05-13 | 2002-11-12 | 2003-05-14 | $7700.00 | Window Closed / Lapsed |