Polydentate metal salts used in the process for the deactivation of glass surfaces and capillary columns therewith

Claim 1

A process for deactivating glass capillary columns which comprises treating the internal surfaces of a capillary column with one or more deactivating polydentate salts either prior to or in conjunction with the application of liquid substrate capable of separating complex mixtures of compounds using gas chromatographic techniques wherein the said columns are operated up to 300° C. and above and wherein the salts comprise the reaction product of (a) a polydentate compound containing two or more quaternizable group V-A elements of the following formula: (1) R 1 R 2 MAMR 1 R 2 ; (2) (R 1 R 2 MA) 3 M; (3) (R 1 R 2 MA) 2 MR 3 ; (4) (R 1 R 2 MA) 2 MAM(AMR 1 R 2 ) 2 ; and ##STR2## wherein M is independently a group V-A element selected from the group consisting of phosphorus, antimony and arsenic; R 1 , R 2 and R 3 are the same or different C 1-20 alkyl radical, or an aromatic radical containing up to twelve carbon atoms and A represents a straight chain or branched lower alkylene radical containing from 2 to 6 carbons; n is an integer from 1 to 6; and (b) a quaternary salt forming mono or difunctional alkyl or aralkyl halide selected from the group consisting of (1) R 4 X; (2) ArR 5 X; (3) XR 6 X; and (4) XCH 2 MCH 2 X wherein X is halogen; R 4 is an alkyl radical containing 2 to 6 carbon atoms; R 6 is lower alkylene radical containing 2 to 6 carbon atoms; Ar is a mono or divalent aryl radical which may contain one or more halogen ring substituents.